MICR 290 Final Exam Questions with Correct Answers| Latest Update Guaranteed Success
Polymyxins (against Gram -) -Disruption of cytoplasmic membrane
-Amphotericin B attaches to ergosterol in fungal membranes and disrupts cytoplasmic
membrane
-Azoles inhibit ergosterol synthesis (used as anti fungal, anti protozoa and worm infections
Innate immunity -Resistance to most plan and animals pathogens
-Species resistance: physiological processes of humans that are incompatible with those of a
pathogen
-Humans don't have innate resistance to some pathogens
Adaptive immunity (what is it, 2 types, 5 attributes?) -Body's ability to recognize and defend
itself against distinct invaders and their products (3rd line of defense)
2 Types:
-Humoral immune response (antibody)
-Cell mediated immune response (T-killer cells)
5 attributes:
-Specificity
-Inducibility
-Clonality
-Unresponsiveness to self
,-Memory
ELISA (what is it, how does it work, 2 types?) -Enzyme-Linked Immunosorbent Assay
-Use of antibodies to detect antigens in the patients serum
2 Types:
-Direct: pregnancy test
-Indirect: HIV test
Acyclovir -Lessen genital herpes symptoms
-Doesn't cure it
AZT (anti-HIV) -Azido-Dideoxythymidxine
Prion protein (parasitic particle) (what is it, 2 types?) -Infectious protein contracted by
eating meat from infected cattle; proteinaceous infectious agents
2 types:
(prion PrP changes shape of cellular PrP so it becomes prion PrP)
-Cellular PrP protein: made by all mammals with a-helices called cellular PrP
-Prion PrP: disease causing with B-pleated sheets called prion PrP
Viroid -Very small, circular pieces of RNA that are infectious/pathogenic in plants
, Bacillus anthracis -Causes cutaneous anthrax
-Occurs when anthrax spores get into skin (usually through cut/scrape)
-Characterized by eschar (black, painless, ulcer)
-Bioterrorism tool (spores can be mailed)
Bordetella pertussis -Causes pertussis (whooping cough)
-Pertussis progresses through 4 phases: incubation, catarrhal, paroxysmal, convalescent
Borrelia burgdorferi 3 phases in untreated patients:
-Bull's eye rash at infection site
-Neurological symptoms
-Severe arthritis
Spirochete borrelia burgdorferi causes lyme disease
Chlamydia trachomatis -Causes chlamydia
-Lympthogranuloma venereum causes a genital lesion and bubo in the groin
Developmental cycle:
-Elementary bodies are the infective non-productive form
-Reticulate bodies are the non-infective reproductive form
Polymyxins (against Gram -) -Disruption of cytoplasmic membrane
-Amphotericin B attaches to ergosterol in fungal membranes and disrupts cytoplasmic
membrane
-Azoles inhibit ergosterol synthesis (used as anti fungal, anti protozoa and worm infections
Innate immunity -Resistance to most plan and animals pathogens
-Species resistance: physiological processes of humans that are incompatible with those of a
pathogen
-Humans don't have innate resistance to some pathogens
Adaptive immunity (what is it, 2 types, 5 attributes?) -Body's ability to recognize and defend
itself against distinct invaders and their products (3rd line of defense)
2 Types:
-Humoral immune response (antibody)
-Cell mediated immune response (T-killer cells)
5 attributes:
-Specificity
-Inducibility
-Clonality
-Unresponsiveness to self
,-Memory
ELISA (what is it, how does it work, 2 types?) -Enzyme-Linked Immunosorbent Assay
-Use of antibodies to detect antigens in the patients serum
2 Types:
-Direct: pregnancy test
-Indirect: HIV test
Acyclovir -Lessen genital herpes symptoms
-Doesn't cure it
AZT (anti-HIV) -Azido-Dideoxythymidxine
Prion protein (parasitic particle) (what is it, 2 types?) -Infectious protein contracted by
eating meat from infected cattle; proteinaceous infectious agents
2 types:
(prion PrP changes shape of cellular PrP so it becomes prion PrP)
-Cellular PrP protein: made by all mammals with a-helices called cellular PrP
-Prion PrP: disease causing with B-pleated sheets called prion PrP
Viroid -Very small, circular pieces of RNA that are infectious/pathogenic in plants
, Bacillus anthracis -Causes cutaneous anthrax
-Occurs when anthrax spores get into skin (usually through cut/scrape)
-Characterized by eschar (black, painless, ulcer)
-Bioterrorism tool (spores can be mailed)
Bordetella pertussis -Causes pertussis (whooping cough)
-Pertussis progresses through 4 phases: incubation, catarrhal, paroxysmal, convalescent
Borrelia burgdorferi 3 phases in untreated patients:
-Bull's eye rash at infection site
-Neurological symptoms
-Severe arthritis
Spirochete borrelia burgdorferi causes lyme disease
Chlamydia trachomatis -Causes chlamydia
-Lympthogranuloma venereum causes a genital lesion and bubo in the groin
Developmental cycle:
-Elementary bodies are the infective non-productive form
-Reticulate bodies are the non-infective reproductive form
