AG-ACNP Board Certification exam
2025 Questions and Answers
TIBC - ANSWER✔✔-total iron binding capacity
normal - 250-450
Higher iron binding capacity need mean GREATER need for iron
MCV - ANSWER✔✔-Mean corpuscular volume-average volume or size of a single red
blood cell
Normal: 80-100
<80 - microcytic
80-100 - normocytic
>100 - macrocytic
MCHC - ANSWER✔✔-Mean Corpuscular Hgb Concentration
Normal: 32-36%
< 32% - Hypochromic
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,32-36% - normochromic
> 36% - hyperchromic
Low MCV diseases - ANSWER✔✔-Iron deficiency anemia
Thalassemia
High MCV diseases - ANSWER✔✔-B12 or Folate deficiency
ETOH
Liver failure
Drug effects
Normocyctic anemia diseases - ANSWER✔✔-Anemia of chronic diseases
sickle cell
renal failure
blood loss
hemolysis
iron deficiency anemia - ANSWER✔✔-slow onset, few sx w/ Hct > 30
Low serum ferritin
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,High TIBC
High RDW (red cell distribution width)
Positive Brudzinski's sign - ANSWER✔✔-is flexion of the hips and knees when the neck
is flexed
Likely meningitis!
Syphilis - ANSWER✔✔-4 stages
Dx: VDRL or RPR --> then confirm with TP-PA or FTA-ABS (treponemal test)
Tx: Penicillin G, if allergic --> Doxy or Tetra
pulseless ventricular tachycardia (VT) defibrillation - ANSWER✔✔-150-200 J on
biphasic and 360 J on a monophasic defibrillator
cerebral perfusion pressure (CPP) calc? - ANSWER✔✔-MAP - ICP
Normal: 60-80
acute muscle strain Tx - ANSWER✔✔-NSAIDS
Cyclobenzaprine (muscle relaxant)
Acute anal fissures tx - ANSWER✔✔-sitz baths, stool softeners, and topical
corticosteroids
COPYRIGHT © 2025 ALL RIGHTS RESERVED
, Chronic anal fissures tx - ANSWER✔✔-topical nitroglycerin or botulinum toxin
injections
Meningitis - ANSWER✔✔-Acute bacterial meningitis --> medical emergency
Pathogens: Strep pneumoniae, Hemophilus influenzae, Neisseria meningitidis
Sx: Fever, severe HA, n/v, NUCHAL RIGIDITY (stiff neck), photophobia
Positive Kernig's sign: pain and spasms of hamstirng muscles
Positive Brudzinki's sign
Dx: LP --> CSF cloudy or xanthocrhomic (yellow)
Elevated protein & decreased GLU --> Bacterial!
CT head if indicated
Tx: Dexamethasone (steroid) before Abx
Abx: Ampicillin + Vancomycin + Ceftriaxone
Cushing's Syndrome - ANSWER✔✔-hypersectrion of ACTH from pituitary
Sx: Moon face, central obesity, HTN
COPYRIGHT © 2025 ALL RIGHTS RESERVED
2025 Questions and Answers
TIBC - ANSWER✔✔-total iron binding capacity
normal - 250-450
Higher iron binding capacity need mean GREATER need for iron
MCV - ANSWER✔✔-Mean corpuscular volume-average volume or size of a single red
blood cell
Normal: 80-100
<80 - microcytic
80-100 - normocytic
>100 - macrocytic
MCHC - ANSWER✔✔-Mean Corpuscular Hgb Concentration
Normal: 32-36%
< 32% - Hypochromic
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,32-36% - normochromic
> 36% - hyperchromic
Low MCV diseases - ANSWER✔✔-Iron deficiency anemia
Thalassemia
High MCV diseases - ANSWER✔✔-B12 or Folate deficiency
ETOH
Liver failure
Drug effects
Normocyctic anemia diseases - ANSWER✔✔-Anemia of chronic diseases
sickle cell
renal failure
blood loss
hemolysis
iron deficiency anemia - ANSWER✔✔-slow onset, few sx w/ Hct > 30
Low serum ferritin
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,High TIBC
High RDW (red cell distribution width)
Positive Brudzinski's sign - ANSWER✔✔-is flexion of the hips and knees when the neck
is flexed
Likely meningitis!
Syphilis - ANSWER✔✔-4 stages
Dx: VDRL or RPR --> then confirm with TP-PA or FTA-ABS (treponemal test)
Tx: Penicillin G, if allergic --> Doxy or Tetra
pulseless ventricular tachycardia (VT) defibrillation - ANSWER✔✔-150-200 J on
biphasic and 360 J on a monophasic defibrillator
cerebral perfusion pressure (CPP) calc? - ANSWER✔✔-MAP - ICP
Normal: 60-80
acute muscle strain Tx - ANSWER✔✔-NSAIDS
Cyclobenzaprine (muscle relaxant)
Acute anal fissures tx - ANSWER✔✔-sitz baths, stool softeners, and topical
corticosteroids
COPYRIGHT © 2025 ALL RIGHTS RESERVED
, Chronic anal fissures tx - ANSWER✔✔-topical nitroglycerin or botulinum toxin
injections
Meningitis - ANSWER✔✔-Acute bacterial meningitis --> medical emergency
Pathogens: Strep pneumoniae, Hemophilus influenzae, Neisseria meningitidis
Sx: Fever, severe HA, n/v, NUCHAL RIGIDITY (stiff neck), photophobia
Positive Kernig's sign: pain and spasms of hamstirng muscles
Positive Brudzinki's sign
Dx: LP --> CSF cloudy or xanthocrhomic (yellow)
Elevated protein & decreased GLU --> Bacterial!
CT head if indicated
Tx: Dexamethasone (steroid) before Abx
Abx: Ampicillin + Vancomycin + Ceftriaxone
Cushing's Syndrome - ANSWER✔✔-hypersectrion of ACTH from pituitary
Sx: Moon face, central obesity, HTN
COPYRIGHT © 2025 ALL RIGHTS RESERVED
