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• Incorrect copying of the DNA sequence/
Environmental
•Exposure
•Spontaneous
,Xlinked recessive disorder examples
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hemophilia A, MD
Hypovolemia
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hypertonic state caused by primary free water loss
locus
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Location of a gene on a chromosome
Fat necrosis
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cellular breakdown by lipase = releasing fatty acids causing soaps when
binding with calcium, magnesium, sodium (Breast, pancreas, ABD)
,example of anaplasia
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hallmark to cancer
Dysplasia
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abnormal change is size, shape and organization of cells
respiratory alkalosis
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pH > 7.45, PaCO2 < 35, HCO3 normal
Metaplasia
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reversible replacement of one mature cell type by another less mature cell
type
, Exocytosis
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Process by which a cell releases large molecules from intracellular
environment
Increased capillary hydrostatic pressure, decreased plasma oncotic pressure and
increased capillary permeability can cause:
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edema
autosomal recessive disorders example
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Tay-Sachs, Cystic fibrosis, sickle cell anemia, phenylketonuria
gangrenous
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tissue death resulting from severe hypoxic injury example is legs