NSG533 / NSG 533 Exam 1 (Latest ):
Advanced Pharmacology | Questions and
Verified Answers with Rationales | 100% Correct |
Grade A - Wilkes
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Terms in this set (211)
1. Etiology
2. Epidemiology
5 essential components of
3. Pathogenesis
pathophysiology
4. Clinical Manifestations
5. Outcomes
other terms for "unknown" idiopathic and cryptogenic
etiology of disease
etiology of disease as a result of surgical/medical
define iatrogenic
intervention
define incidence of the new number of cases in a given population in a
epidemiology specific time period
define prevalence of number of cases, both old and new, during a specific
epidemiology time period
1. ATP Depletion
what are the four common
2. Oxygen and oxygen-derived free radicals
mechanisms of cell injury
3. intracellular calcium and loss of calcium state
and death
4. defects in membrane permeability
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, 5/14/25, 2:31 PM NSG533 / NSG 533 Exam 1 (Latest ): Advanced Pharmacology | Questions and Verified Answers with Rationales | 100…
what is the most common ATP deletion
stressor of disease
what are the two phases 1. Anaerobic (glycolysis)
of ATP production? 2. Aerobic (oxidative phosphorylation)
how many ATP does 2
glycolysis yield?
How many ATP does 36
oxidative phosphorylation
yield?
in ATP depletion, what are 1. Hypoxia
the four critical points 2.
where ATP production
may be impaired?
ischemia reduced blood flow
obstruction --> ischemia --> decreased ATP
Explain hypoxia in terms
production --> a) sodium/potassium ion pump fails,
of ATP depletion
and b) increased anaerobic glycolysis
normally, most sodium ions are outside the cell and
most potassium ions are inside the cell
explain what happens
when the Na-K-ATPase when the pump fails, sodium freely enters the cell with
pump fails due to H2O and calcium, and potassium freely exits the cell
decreased ATP production
as a result, the cell swells and and protein synthesis
stops
where does protein Rough ER with ribosomes on the surface
synthesis occur in a cell?
glycogen is decreased, lactate is increased,
explain what happens
intracellular pH is decreased
where there is an increase
in glycolysis due to
decreased pH results in pyknosis, karyorrhexis, and
decreased ATP production
karyolysis
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