Microbiology HCC Ultimate Exam Guide 2025 |
Verified Answer Key | Guaranteed High Marks
Amantidine Application - Prevents influenzae type A virus
Amantadine Problems - Causes insomnia & ataxia (inability to coordinate voluntary
movements)
Aminoglycosise Definition - 2 or more amino acids
Origin species: Streptomycin, Micromonospora
Aminoglycoside Mode of Action - Inhibits protein synthesis
Aminoglycoside Applications - Bone & Joint infections
Aminoglycoside Problems - Damage kidney cells
Damage CN#8
Dizzy, hearing loss
Amphotericin B Mode of Action - Binds to plasma memebrane in fungi, algae, Protozoa
Amphotericin B Definition - Antifugal antibiotic derived from strepomyces nodosus
Amphotericin B Application - Cryptococcosis, coccidiomycosis, aspergillosis
Amphotericin B Problems - Toxic
IV only
Poorly absorbed from the GI tract
AZT Mode of Action - Interferes with the reverse transcriptase from making DNA from
RNA
AZT Application - Treat HIV
Beta-lactamase - enzyme that breaks the beta-lactam ring of penicillin druga
Cephalosporins - Have beta lactate ring structure
Cephalosporins Mode of Action - Kills bacteria by inhibiting cell wall synthesis
Cephalosporins Problems - Poorly absorbed from the intestine.
, Administered by injection into muscle or vein
Cephalosporins 1st generation - Most effective five against gram + cocci
Cephalosporins 2nd generation - More effective with gram - & anaerobics
IV only
Cephalosporins 3rd generation - IV only
Will cross BBB, recommended for meningitis
Chloramphenicol definition - Synthesized only man
When all else fails
Chloramphenicol applications - Thyroid fever
Brain abcesses
Rickettsial
Chloramphenicol Mode of Action - Protein synthesis inhibitor
Bacteriostatic
Chloramphenicol Problem - Bone marrow is destroyed -a plastic anemia
Inflammation of the optics confusion
Fliroquinolones - cipro - New group of synthetic bacteriocidal analogues
Fliroquinolones - cipro Mode of Action - Inhibit DNA synthesis in the cell
Blocks DNA gyrase
Fliroquinolones - cipro Application - Travelers diarrhea, UTI
Use on pseudomonas
Fliroquinolones - cipro Problems - Brain seizures, CNA damage
Streptomycin definition - Damage kidney, inner ear s
Sulfonamides definition the first sulfa drug
A chemical, synthesized was -
Super infections - Invasion by opportunistic microbes to replace the normal bacteria
Verified Answer Key | Guaranteed High Marks
Amantidine Application - Prevents influenzae type A virus
Amantadine Problems - Causes insomnia & ataxia (inability to coordinate voluntary
movements)
Aminoglycosise Definition - 2 or more amino acids
Origin species: Streptomycin, Micromonospora
Aminoglycoside Mode of Action - Inhibits protein synthesis
Aminoglycoside Applications - Bone & Joint infections
Aminoglycoside Problems - Damage kidney cells
Damage CN#8
Dizzy, hearing loss
Amphotericin B Mode of Action - Binds to plasma memebrane in fungi, algae, Protozoa
Amphotericin B Definition - Antifugal antibiotic derived from strepomyces nodosus
Amphotericin B Application - Cryptococcosis, coccidiomycosis, aspergillosis
Amphotericin B Problems - Toxic
IV only
Poorly absorbed from the GI tract
AZT Mode of Action - Interferes with the reverse transcriptase from making DNA from
RNA
AZT Application - Treat HIV
Beta-lactamase - enzyme that breaks the beta-lactam ring of penicillin druga
Cephalosporins - Have beta lactate ring structure
Cephalosporins Mode of Action - Kills bacteria by inhibiting cell wall synthesis
Cephalosporins Problems - Poorly absorbed from the intestine.
, Administered by injection into muscle or vein
Cephalosporins 1st generation - Most effective five against gram + cocci
Cephalosporins 2nd generation - More effective with gram - & anaerobics
IV only
Cephalosporins 3rd generation - IV only
Will cross BBB, recommended for meningitis
Chloramphenicol definition - Synthesized only man
When all else fails
Chloramphenicol applications - Thyroid fever
Brain abcesses
Rickettsial
Chloramphenicol Mode of Action - Protein synthesis inhibitor
Bacteriostatic
Chloramphenicol Problem - Bone marrow is destroyed -a plastic anemia
Inflammation of the optics confusion
Fliroquinolones - cipro - New group of synthetic bacteriocidal analogues
Fliroquinolones - cipro Mode of Action - Inhibit DNA synthesis in the cell
Blocks DNA gyrase
Fliroquinolones - cipro Application - Travelers diarrhea, UTI
Use on pseudomonas
Fliroquinolones - cipro Problems - Brain seizures, CNA damage
Streptomycin definition - Damage kidney, inner ear s
Sulfonamides definition the first sulfa drug
A chemical, synthesized was -
Super infections - Invasion by opportunistic microbes to replace the normal bacteria
