answers
Management of BMI >/= 25 - CORRECT ANSWERS ✔✔Diet, Exercise,
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Behavior
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Management of BMI >/=30 - CORRECT ANSWERS ✔✔Diet, exercise,
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behavior + pharmacotherapy
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Management of BMI >/= 27 + comorbidity - CORRECT ANSWERS
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✔✔Diet, exercise, behavior + pharmacotherapy
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Management of BMI >/=35 + cormorbidity - CORRECT ANSWERS
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✔✔Bariatric surgery
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Management of BMI >/=40 - CORRECT ANSWERS ✔✔Bariatric
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surgery
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Co-morbidities - CORRECT ANSWERS ✔✔T2DM |/\ |/\ |/\ |/\
HTN
OSA and other respiratory disorders
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NAFLD
,OA
lipid abnormalities
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gastrointestinal disorders |/\
heart disease
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Medication assessment - CORRECT ANSWERS ✔✔Every month x3
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months, then every 3 months
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Effective weight loss % - CORRECT ANSWERS ✔✔>/=5% in 3
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months
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Avoid these wt loss meds with HTN/HD - CORRECT ANSWERS
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✔✔Sympathomimetics (phentermine/diethylproprion)
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Avoid these wt loss medications with CVD - CORRECT ANSWERS
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✔✔Sypathomimetics
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T2DM treatment + medications to support weight loss - CORRECT
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ANSWERS ✔✔GLP-1 analog (mitigates associated weight gain due to
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insulin) or SGLT-2 inhibitors + metformin. If using insulin,
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recommend basal instead of combo
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,Drugs that induce weight gain - CORRECT ANSWERS ✔✔Tricyclic
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antidepressants (Amitriptyline)
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oral contraceptives (Ortho Tri-Cyclen, Yaz)
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antipsychotics (Risperidone) |/\
anticonvulsants |/\
glucocorticoids (cortisol) |/\ |/\
sulfonyureas- ( Glimepiride, Glipizide) |/\ |/\ |/\ |/\
glitazones (Actos) |/\ |/\
B-blockers (Propranolol, Metoprolol, Atenolol) |/\ |/\ |/\
Hormonal signals for appetite - CORRECT ANSWERS ✔✔CCK-
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duodenum
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K cells- duodenum and jejunum: gatric inhibitory polypeptide
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PYY- ileum and colon
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GLP-1 -ileum |/\
Pancreas- Insulin |/\ |/\
Adipose tissue: Leptin |/\ |/\ |/\
Liver- glucagon |/\
, GLP-1 - CORRECT ANSWERS ✔✔Secreted in response to glucose and
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promotes insulin release from pancreas and satiety
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Ghrelin - CORRECT ANSWERS ✔✔produced in the stomach,
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orexigenic
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Leptin - CORRECT ANSWERS ✔✔proportional to fat mass,
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anorexigenic
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Inhibits appetite |/\
PYY - CORRECT ANSWERS ✔✔Ileum and colon, anorexigenic
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CCK - CORRECT ANSWERS ✔✔duodenum, anorexigenic
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Insulin - CORRECT ANSWERS ✔✔Pancreas, anorexigenic
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Phentermine - CORRECT ANSWERS ✔✔noradrenergic, dopaminergic |/\ |/\ |/\ |/\ |/\
sympathomimetic amine
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Start with 7.5-15mg/d, increase only with no results
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