PHARM 180 Quiz 5 Study Guide and Practice
Questions
1. Hyperlipidemia High levels of lipids in blood
2. Hyperlipidemia—major risk factor for... cardiovascular disease
3. Hyperlipidemia contributers.... Diets high in saturated fat and lack of exercise
4. 3 types of lipoproteins high-density lipoprotein (H D L), low-density
lipoprotein (L D L), very low-density lipoprotein
(V L D L)
5. Treatment plan for reducing blood lipid Lifestyle changes (�rst)
levels... Many patients can control dyslipidemia entirely
through nonpharmacologic means
6. Lifestyle changes for reducing blood -Maintain optimal weight**
lipid levels include... -Implement a medically supervised
-Eliminate tobacco use**
7. Total cholesterol levels less than 200 desirable**
8. High Total cholesterol level 240
e
9. Optimal LDL cholesterol levels less than 100mg/dl
10. High LDL level 160
e
11. Desirable HDL cholesterol levels 60+ mg/dl (good)
12. Normal Serum Triglyceride levels less than 150
13. High Serum triglycerides level 200
e
14. Low HDL for men d40
d40 (men) or 50 (women)
,15. Low HDL for women d50
16. Foods allowed for lipid reducing diet Rice, broccoli, walnuts, apples, rye and
whole-wheat bread, low- fat brownies, fresh
fruits, tossed salad with olive oil, and grilled
chicken/salmon.
17. Foods allowed for lipid increasing diet Any meat with gravy, apple pie, pecans, mac-
aroni and cheese, and low fat hamburger,
raisin-oatmeal cookie
18. Medication for high LDL Cholesterol Statins - atorvastatin (Lipitor)
19. Medication for high Total cholesterol Bile Acids
1. Bile Acid Sequestrants
-colesevelam (Welchol)
-colestipol (Colestid)
2. Bile-Acid Resins -cholestyramine (Questran)
20. Medication for high Serum triglcerides �bric acids
21. Serious adverse e�ects of atorvastatin Rhabdomyolysis, severe myositis, elevated he-
(Lipitor) patic enzymes
22. Serious adverse e�ects for cholestyra- GI tract obstruction, vitamin de�ciencies due to
mine (Questran) poor absorption
23. Serious adverse efects for Gem brozil Rhabdomyolysis, cholelithiasis, pancreatitis
(Lopid)
24. Role of the nurse for dyslipidema.. Assess patient's triglyceride, total cholesterol,
LDL, and HDL levels. MUST HAVE BASELINE***
25. HMG-CoA Reductase Inhibitors/Statins
, atorvastatin (Lipitor), uvastatin (Le-
scol), lovastatin (Mevacor), rosuvastatin
(Crestor), simvastatin (Zocor)
Are examples of...
26. Rhabdomyolysis dissolution of striated muscle (caused by trau-
ma, extreme exertion, or drug toxicity; in severe
cases renal failure can result)
27. Atorvastatin (Lipitor) therapeutic class... Antihyperlipidemic
28. Atorvastatin (Lipitor) considerations... Blood levels of both LDL and cholesterol are
reduced, although at least 2 weeks of therapy
is required before these e ects are realized.
To enhance the drug's therapeutic e ects, pa-
tients receiving atorvastatin should be placed
on a cholesterol-lowering diet.
29. Atorvastatin (Lipitor) contraindica- Serious liver disease (HEP C**)
tions...
30. Atorvastatin (Lipitor) drug-drug interac- Azole antifungals, HIV protease inhibitors, and
tions.. telaprevir.
**Increased risk for myopathy and rhabdomy-
olysis. **
31. Concurrent administration of atorvas- rhabdomyolysis
tatin with macrolide antibiotics, cy-
closporine, and niacin increases risk for..
32. Statins also decrease the synthesis of Omega-3 & C o Q10 supplements.
coenzyme Q10 (CoQ10). Patients may Sardines, nuts - almonds, olive and canola oils
bene t from...
Questions
1. Hyperlipidemia High levels of lipids in blood
2. Hyperlipidemia—major risk factor for... cardiovascular disease
3. Hyperlipidemia contributers.... Diets high in saturated fat and lack of exercise
4. 3 types of lipoproteins high-density lipoprotein (H D L), low-density
lipoprotein (L D L), very low-density lipoprotein
(V L D L)
5. Treatment plan for reducing blood lipid Lifestyle changes (�rst)
levels... Many patients can control dyslipidemia entirely
through nonpharmacologic means
6. Lifestyle changes for reducing blood -Maintain optimal weight**
lipid levels include... -Implement a medically supervised
-Eliminate tobacco use**
7. Total cholesterol levels less than 200 desirable**
8. High Total cholesterol level 240
e
9. Optimal LDL cholesterol levels less than 100mg/dl
10. High LDL level 160
e
11. Desirable HDL cholesterol levels 60+ mg/dl (good)
12. Normal Serum Triglyceride levels less than 150
13. High Serum triglycerides level 200
e
14. Low HDL for men d40
d40 (men) or 50 (women)
,15. Low HDL for women d50
16. Foods allowed for lipid reducing diet Rice, broccoli, walnuts, apples, rye and
whole-wheat bread, low- fat brownies, fresh
fruits, tossed salad with olive oil, and grilled
chicken/salmon.
17. Foods allowed for lipid increasing diet Any meat with gravy, apple pie, pecans, mac-
aroni and cheese, and low fat hamburger,
raisin-oatmeal cookie
18. Medication for high LDL Cholesterol Statins - atorvastatin (Lipitor)
19. Medication for high Total cholesterol Bile Acids
1. Bile Acid Sequestrants
-colesevelam (Welchol)
-colestipol (Colestid)
2. Bile-Acid Resins -cholestyramine (Questran)
20. Medication for high Serum triglcerides �bric acids
21. Serious adverse e�ects of atorvastatin Rhabdomyolysis, severe myositis, elevated he-
(Lipitor) patic enzymes
22. Serious adverse e�ects for cholestyra- GI tract obstruction, vitamin de�ciencies due to
mine (Questran) poor absorption
23. Serious adverse efects for Gem brozil Rhabdomyolysis, cholelithiasis, pancreatitis
(Lopid)
24. Role of the nurse for dyslipidema.. Assess patient's triglyceride, total cholesterol,
LDL, and HDL levels. MUST HAVE BASELINE***
25. HMG-CoA Reductase Inhibitors/Statins
, atorvastatin (Lipitor), uvastatin (Le-
scol), lovastatin (Mevacor), rosuvastatin
(Crestor), simvastatin (Zocor)
Are examples of...
26. Rhabdomyolysis dissolution of striated muscle (caused by trau-
ma, extreme exertion, or drug toxicity; in severe
cases renal failure can result)
27. Atorvastatin (Lipitor) therapeutic class... Antihyperlipidemic
28. Atorvastatin (Lipitor) considerations... Blood levels of both LDL and cholesterol are
reduced, although at least 2 weeks of therapy
is required before these e ects are realized.
To enhance the drug's therapeutic e ects, pa-
tients receiving atorvastatin should be placed
on a cholesterol-lowering diet.
29. Atorvastatin (Lipitor) contraindica- Serious liver disease (HEP C**)
tions...
30. Atorvastatin (Lipitor) drug-drug interac- Azole antifungals, HIV protease inhibitors, and
tions.. telaprevir.
**Increased risk for myopathy and rhabdomy-
olysis. **
31. Concurrent administration of atorvas- rhabdomyolysis
tatin with macrolide antibiotics, cy-
closporine, and niacin increases risk for..
32. Statins also decrease the synthesis of Omega-3 & C o Q10 supplements.
coenzyme Q10 (CoQ10). Patients may Sardines, nuts - almonds, olive and canola oils
bene t from...
