Exam Questions and CORRECT Answers
clotting - CORRECT ANSWER - the coagulation of blood caused by the rupture of
platelets and the interaction of fibrin, fibrinogen, thrombin, prothrombin and calcium ions
thrombus - CORRECT ANSWER - blood clot
embolus - CORRECT ANSWER - A clot that breaks lose and travels through the
bloodstream.
Thrombocytopenia - CORRECT ANSWER - low platelet count
Polycythemia - CORRECT ANSWER - A disorder characterized by an abnormal increase
in the number of red blood cells in the blood
Ecchymosis - CORRECT ANSWER - bruise
petechiae - CORRECT ANSWER - small, pinpoint hemorrhages
hemarthrosis - CORRECT ANSWER - blood within a joint
plasmin - CORRECT ANSWER - fibrin-digesting enzyme
Fibrinolysis - CORRECT ANSWER - dissolution of a clot
medications that slow clotting - CORRECT ANSWER - platelet inhibitors, thrombin
inhibitors, vitamin k antagonists, fibrolytic drugs
, platelet inhibitors - CORRECT ANSWER - stop platelets from sticking together and
preventing the formation of clots
ex: aspirin, plavix, brilinta
DIRECT thrombin inhibitors - CORRECT ANSWER - drugs that prevent the conversion
of prothrombin to thrombin, disrupting the clotting cascade and the conversion of fibrinogen to
fibrin
ex: pradaxa, xarelto, eliquis
INDIRECT thrombin inhibitors - CORRECT ANSWER - bind to and increase the activity
of antithrombin III. by activating antithrombin, thrombin is reduced, reducing clot formation and
the conversion of fibrinogen to fibrin
ex: lovenox, heparin
vitamin k antagonist - CORRECT ANSWER - blocks some absorption to the liver
preventing clotting
ex: warfarin
fribrinolytic drugs - CORRECT ANSWER - 87\ak down fibrin threads in present in
formed blood clots. activate plasmin, which breaks down and degrades the fibrin molecules
ex: activase and TNKase
heparin - CORRECT ANSWER - common anticoagulant, iv medication is high risk, often
used for venous blood clots (DVT), PE, and coronary artery occlusions (NSTEMI)