Test Bank
Lehne's Pharmacology For Nursing Care, 11th Edition
By Jacqueline Burchum, Laura Rosenthal |All Chapters ||Complete Guide 2025
,Table Of Contents
Chapter 01: Orientation To Pharmacology ...............................................................................................6
Chapter 02: Application Of Pharmacology In Nursing Practice .......................................................... 8
Chapter 03: Drug Regulation, Development, Names, And Information ......................................... 16
Chapter 04: Pharmacokinetics .................................................................................................................. 20
Chapter 05: Pharmacodynamics ............................................................................................................... 27
Chapter 06: Drug Interactions ....................................................................................................................32
Chapter 07: Adverse Drug Reactions And Medication Errors ............................................................ 39
Chapter 08: Individual Variation To Drug Responses ...........................................................................47
Chapter 09: Genetic And Genomic Considerations ...............................................................................53
Chapter 10: Introduction To Immunomodulators .................................................................................. 57
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding .................................................. 62
Chapter 12: Drug Therapy In Pediatric Patients .................................................................................... 68
Chapter 13: Drug Therapy In Older Adults ...............................................................................................74
Chapter 14: Basic Principles Of Neuropharmacology .............................................................................81
Chapter 15: Physiology Of The Peripheral Nervous System ................................................................. 85
Chapter 16: Muscarinic Agonists ................................................................................................................. 90
Chapter 17: Muscarinic Antagonists ........................................................................................................... 94
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis ..................................... 99
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ....................................................104
Chapter 20: Adrenergic Agonists ...............................................................................................................110
Chapter 21: Adrenergic Antagonists .......................................................................................................... 116
Chapter 22: Indirect-Acting Antiadrenergic Agents ............................................................................ 125
Chapter 23: Introduction To Central Nervous System Pharmacology ............................................. 131
Chapter 24: Drugs For Parkinson Disease .............................................................................................. 136
Chapter 25: Drugs For Alzheimer Disease .............................................................................................. 144
Chapter 26: Drugs For Multiple Sclerosis................................................................................................. 150
Chapter 27: Drugs For Seizure Disorders ................................................................................................. 157
Chapter 28: Drugs For Muscle Spasm And Spasticity .......................................................................... 167
Chapter 29: Local Anesthetics ................................................................................................................... 173
Chapter 30: General Anesthetics .............................................................................................................. 179
,Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Acting Analgesics
...........................................................................................................................................................................187
Chapter 32: Pain Management In Patients With Cancer .................................................................. 195
Chapter 33: Drugs For Headache ............................................................................................................ 205
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ................................................. 212
Chapter 35: Antidepressants ..................................................................................................................... 220
Chapter 36: Drugs For Bipolar Disorder ................................................................................................ 230
Chapter 37: Sedative-Hypnotic Drugs ....................................................................................................237
Chapter 38: Management Of Anxiety Disorders .................................................................................. 246
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder
......................................................................................................................................................................... 252
Chapter 40: Substance Use Disorders I: Basic Considerations ........................................................... 258
Chapter 41: Substance Use Disorders Ii: Alcohol ................................................................................... 263
Chapter 42: Substance Use Disorders Iii: Nicotine .................................................................................273
Chapter 43: Substance Use Disorders Iv: Major Drugs Of Abuse Other Than Alcohol And
Nicotine .......................................................................................................................................................... 279
Chapter 44: Diuretics ...................................................................................................................................288
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ............................... 294
Chapter 46: Review Of Hemodynamics ................................................................................................ 302
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System.................................. 306
Chapter 48: Calcium Channel Blockers ................................................................................................... 312
Chapter 49: Vasodilators ............................................................................................................................ 316
Chapter 50: Drugs For Hypertension...................................................................................................... 322
Chapter 51: Drugs For Heart Failure....................................................................................................... 332
Chapter 52: Antidysrhythmic Drugs ........................................................................................................ 343
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ............................. 354
Chapter 54: Drugs For Angina Pectoris ................................................................................................. 364
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ................................................373
Chapter 56: Management Of St-Elevation Myocardial Infarction ..................................................383
Chapter 57: Drugs For Hemophilia ......................................................................................................... 389
Chapter 58: Drugs For Deficiency Anemias ........................................................................................... 396
Chapter 59: Hematopoietic Agents ........................................................................................................404
Chapter 60: Drugs For Diabetes Mellitus ...............................................................................................410
,Chapter 61: Drugs For Thyroid Disorders ................................................................................................ 419
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function ......................................... 427
Chapter 63: Drugs For Disorders Of The Adrenal Cortex .................................................................. 434
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive
Applications .................................................................................................................................................. 439
Chapter 65: Birth Control .......................................................................................................................... 445
Chapter 66: Drug Therapy For Infertility .............................................................................................. 454
Chapter 67: Drugs That Affect Uterine Function .................................................................................460
Chapter 68: Androgens .............................................................................................................................. 466
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ......................... 473
Chapter 70: Review Of The Immune System ....................................................................................... 479
Chapter 71: Childhood Immunization ..................................................................................................... 485
Chapter 72: Immunosuppressants ........................................................................................................... 493
Chapter 73: Antihistamines ....................................................................................................................... 499
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs And
Acetaminophen ........................................................................................................................................... 507
Chapter 75: Glucocorticoids In Nonendocrine Disorders ..................................................................... 515
Chapter 76: Drug Therapy For Rheumatoid Arthritis ........................................................................ 523
Chapter 77: Drug Therapy For Gout .......................................................................................................527
Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ......................................... 532
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease ............................ 542
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds ............................................................... 553
Chapter 81: Drugs For Peptic Ulcer Disease .......................................................................................... 560
Chapter 82: Laxatives ................................................................................................................................. 568
Chapter 83: Other Gastrointestinal Drugs ............................................................................................. 576
Chapter 84: Vitamins ...................................................................................................................................587
Chapter 85: Drugs For Weight Loss ......................................................................................................... 595
Chapter 86: Complementary And Alternative Therapy ...................................................................602
Chapter 87: Basic Principles Of Antimicrobial Therapy ..................................................................... 608
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins ............................................ 615
Chapter 89: Drugs That Weaken The Bacterial Cell Wall Ii: Other Drugs ..................................... 624
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others
......................................................................................................................................................................... 630
,Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis .................................... 642
Chapter 92: Sulfonamides And Trimethoprim ...................................................................................... 651
Chapter 93: Drug Therapy For Urinary Tract Infections .................................................................... 657
Chapter 94: Antimycobacterial Agents ................................................................................................. 666
Chapter 95: Miscellaneous Antibacterial Drugs ....................................................................................677
Chapter 96: Antifungal Agents ................................................................................................................ 683
Chapter 97: Antiviral Agents I: Drugs For Non-Hiv Viral Infections ................................................ 694
Chapter 98: Antiviral Agents Ii: Drugs For Hiv Infection And Related Opportunistic Infections
......................................................................................................................................................................... 702
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ......................................................... 710
Chapter 100: Antiseptics And Disinfectants ........................................................................................... 716
Chapter 101: Anthelmintics ......................................................................................................................... 721
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents ................................................................ 726
Chapter 103: Antiprotozoal Drugs Ii: Miscellaneous Agents ...............................................................732
Chapter 104: Ectoparasiticides ..................................................................................................................735
Chapter 105: Basic Principles Of Cancer Chemotherapy ................................................................... 742
Chapter 106: Anticancer Drugs I: Cytotoxic Agents.............................................................................. 751
Chapter 107: Anticancer Drugs Ii: Noncytotoxic Agents ..................................................................... 760
Chapter 108: Drugs For The Eye .............................................................................................................. 766
Chapter 109: Drugs For The Skin .............................................................................................................. 773
Chapter 110: Drugs For The Ear.................................................................................................................784
Chapter 111: Management Of Poisoning ................................................................................................. 791
Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism .....................797
,Chapter 01: Orientation To Pharmacology
Burchum: Lehne’s Pharmacology For Nursing Care, 11th Edition
Multiple Choice
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This,
The Nurse Will Rely On Knowledge Of Which Topic?
A. Clinical Pharmacology
B. Drug Efficacy
C. Pharmacokinetics
D. Pharmacotherapeutics
Answer: D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent
Conditions. Clinical Pharmacology Is Concerned With All Aspects Of Drug-Human Interactions.
Drug Efficacy Measures The Extent To Which A Given Drug Causes An Intended Effect.
Pharmacokinetics Is The Study Of The Impact Of The Body On A Drug.
Pts: 1
2. What Is A Desired Outcome When A Drug Is Described As Easy To Administer?
A. It Can Be Stored Indefinitely Without Need For Refrigeration.
B. It Does Not Interact Significantly With Other Medications.
C. It Enhances Patient Adherence To The Drug Regimen.
D. It Is Usually Relatively Inexpensive To Produce.
Answer: C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More
Likely To Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other
Attributes Listed, But Those Properties Are Independent Of Ease Of Administration.
Pts: 1
,3. A Patient Tells The Nurse That An Analgesic He Will Begin Taking May Cause Drowsiness
And Will Decrease Pain Up To 4 Hours At A Time. Based On This Understanding Of The Drug’s
Effects By The Patient, The Nurse Will Anticipate Which Outcome?
A. Decreased Chance Of Having A Placebo Effect
B. Decreased Motivation To Take The Drug
C. Improved Compliance With The Drug Regimen
D. Increased Likelihood Of Drug Overdose
Answer: C
A Drug Is Effective If It Produces The Intended Effects, Even If It Also Produces Side Effects.
Patients Who Understand Both The Risks And Benefits Of Taking A Medication Are More Likely
To Comply With The Drug Regimen.
Pts: 1
Multiple Response
1. What Are Considered The ‘Big Three’ Properties Of An Ideal Drug? (Select All That
Apply.)
A. Irreversible Action
B. Effectiveness
C. Safety
D. Selectivity
E. A Recognizable Trade Name
Answer: B, C, D
The ‘Big Three’ Properties Of The Ideal Drug Are Effectiveness, Safety, And Selectivity. Pts: 1
,2. Before Administering A Medication, What Does The Nurse Need To Know To Evaluate
How Individual Patient Variability Might Affect The Patient’s Response To The Medication?
(Select All That Apply.)
A. Chemical Stability Of The Medication
B. Ease Of Administration
C. Family Medical History
D. Patient’s Age
E. Patient’s Diagnosis
Answer: C, D, E
The Family Medical History Can Indicate Genetic Factors That May Affect A Patient’s Response
To A Medication. Patients Of Different Ages Can Respond Differently To Medications. The
Patient’s Illness Can Affect How Drugs Are Metabolized. The Chemical Stability Of The
Medication And The Ease Of Administration Are Properties Of Drugs.
Pts: 1
Chapter 02: Application Of Pharmacology In Nursing
Practice
Burchum: Lehne’s Pharmacology For Nursing Care, 11th Edition
Multiple Choice
1. A Patient Is Using A Metered-Dose Inhaler Containing Albuterol For Asthma. The
Medication Label Instructs The Patient To Administer “2 Puffs Every 4 Hours As Needed For
Coughing Or Wheezing.” The Patient Reports Feeling Jittery Sometimes When Taking The
Medication, And Doesn’t Feel That The Medication Is Always Effective. Which Action Is Outside
The Nurse’s Scope Of Practice?
A. Asking The Patient To Demonstrate The Use Of The Inhaler
B. Assessing The Patient’s Exposure To Tobacco Smoke
,C. Auscultating Lung Sounds And Obtaining Vital Signs
D. Suggesting That The Patient Use 1 Puff To Reduce Side Effects
Answer: D
It Is Not Within The Nurse’s Scope Of Practice To Change The Dose Of A Medication Without An
Order From A Prescriber. Asking The Patient To Demonstrate Inhaler Use Helps The Nurse To
Evaluate The Patient’s Ability To Administer The Medication Properly And Is Part Of The Nurse’s
Evaluation.
Assessing Tobacco Smoke Exposure Helps The Nurse Determine Whether Nondrug Therapies,
Such A Smoke Avoidance, Can Be Used As An Adjunct To Drug Therapy. Performing A Physical
Assessment Helps The Nurse Evaluate The Patient’s Response To The Medication.
Pts: 1
2. A Postoperative Patient Is Being Discharged Home With Acetaminophen/Hydrocodone
[Norco] For Pain. The Patient Asks The Nurse About Using Tylenol For Fever. Which Statement By
The Nurse Is Correct?
A. “It Is Not Safe To Take Over-The-Counter Drugs With Prescription Medications.”
B. “Taking The Two Medications Together Poses A Risk Of Drug Toxicity.”
C. “There Are No Known Drug Interactions, So This Will Be Safe.”
D. “Tylenol And Norco Are Different Drugs, So There Is No Risk Of Overdose.”
Answer: B
Tylenol Is The Trade Name And Acetaminophen Is The Generic Name For The Same Medication.
It Is Important To Teach Patients To Be Aware Of The Different Names For The Same Drug To
Minimize The Risk Of Overdose. Over-The-Counter (Otc) Medications And Prescription
Medications May Be Taken Together Unless Significant Harmful Drug Interactions Are Possible.
Even Though No Drug Interactions Are At Play In This Case, Both Drugs Contain Acetaminophen,
Which Could Lead To Toxicity.
Pts: 1
, 3. The Nurse Is Preparing To Care For A Patient Who Will Be Taking An Antihypertensive
Medication. Which Action By The Nurse Is Part Of The Assessment Step Of The Nursing Process?
A. Asking The Prescriber For An Order To Monitor Serum Drug Levels
B. Monitoring The Patient For Drug Interactions After Giving The Medication
C. Questioning The Patient About Over-The-Counter Medications
D. Taking The Patient’s Blood Pressure Throughout The Course Of Treatment
Answer: C
The Assessment Part Of The Nursing Process Involves Gathering Information Before Beginning
Treatment, And This Includes Asking About Other Medications The Patient May Be Taking.
Monitoring Serum Drug Levels, Watching For Drug Interactions, And Checking Vital Signs After
Giving The Medication Are All Part Of The Evaluation Phase.
Pts: 1
4. A Postoperative Patient Reports Pain, Which The Patient Rates As An 8 On A Scale From
1 To 10 (10 Being The Most Extreme Pain). The Prescriber Has Ordered Acetaminophen [Tylenol]
650 Mg Po Every 6 Hours Prn Pain. What Will The Nurse Do?
A. Ask The Patient What Medications Have Helped With Pain In The Past.
B. Contact The Provider To Request A Different Analgesic Medication.
C. Give The Pain Medication And Reposition The Patient To Promote Comfort.
D. Request An Order To Administer The Medication Every 4 Hours.
Answer: B
The Nursing Diagnosis For This Patient Is Severe Pain. Acetaminophen Is Given For Mild To
Moderate Pain, So The Nurse Should Ask The Prescriber To Order A Stronger Analgesic
Medication. Asking The Patient To Tell The Nurse What Has Helped In The Past Is Part Of An
Initial Assessment And Should Be Done Preoperatively And Not When The Patient Is Having
Severe Pain. Because The Patient Is Having Severe Pain, Acetaminophen Combined With
Nondrug Therapies Will Not Be Sufficient. Increasing The Frequency Of The Dose Of A
Medication For Mild Pain Will Not Be Effective.
Lehne's Pharmacology For Nursing Care, 11th Edition
By Jacqueline Burchum, Laura Rosenthal |All Chapters ||Complete Guide 2025
,Table Of Contents
Chapter 01: Orientation To Pharmacology ...............................................................................................6
Chapter 02: Application Of Pharmacology In Nursing Practice .......................................................... 8
Chapter 03: Drug Regulation, Development, Names, And Information ......................................... 16
Chapter 04: Pharmacokinetics .................................................................................................................. 20
Chapter 05: Pharmacodynamics ............................................................................................................... 27
Chapter 06: Drug Interactions ....................................................................................................................32
Chapter 07: Adverse Drug Reactions And Medication Errors ............................................................ 39
Chapter 08: Individual Variation To Drug Responses ...........................................................................47
Chapter 09: Genetic And Genomic Considerations ...............................................................................53
Chapter 10: Introduction To Immunomodulators .................................................................................. 57
Chapter 11: Drug Therapy During Pregnancy And Breast-Feeding .................................................. 62
Chapter 12: Drug Therapy In Pediatric Patients .................................................................................... 68
Chapter 13: Drug Therapy In Older Adults ...............................................................................................74
Chapter 14: Basic Principles Of Neuropharmacology .............................................................................81
Chapter 15: Physiology Of The Peripheral Nervous System ................................................................. 85
Chapter 16: Muscarinic Agonists ................................................................................................................. 90
Chapter 17: Muscarinic Antagonists ........................................................................................................... 94
Chapter 18: Cholinesterase Inhibitors And Their Use In Myasthenia Gravis ..................................... 99
Chapter 19: Drugs That Block Nicotinic Cholinergic Transmission ....................................................104
Chapter 20: Adrenergic Agonists ...............................................................................................................110
Chapter 21: Adrenergic Antagonists .......................................................................................................... 116
Chapter 22: Indirect-Acting Antiadrenergic Agents ............................................................................ 125
Chapter 23: Introduction To Central Nervous System Pharmacology ............................................. 131
Chapter 24: Drugs For Parkinson Disease .............................................................................................. 136
Chapter 25: Drugs For Alzheimer Disease .............................................................................................. 144
Chapter 26: Drugs For Multiple Sclerosis................................................................................................. 150
Chapter 27: Drugs For Seizure Disorders ................................................................................................. 157
Chapter 28: Drugs For Muscle Spasm And Spasticity .......................................................................... 167
Chapter 29: Local Anesthetics ................................................................................................................... 173
Chapter 30: General Anesthetics .............................................................................................................. 179
,Chapter 31: Opioid Analgesics, Opioid Antagonists, And Nonopioid Centrally Acting Analgesics
...........................................................................................................................................................................187
Chapter 32: Pain Management In Patients With Cancer .................................................................. 195
Chapter 33: Drugs For Headache ............................................................................................................ 205
Chapter 34: Antipsychotic Agents And Their Use In Schizophrenia ................................................. 212
Chapter 35: Antidepressants ..................................................................................................................... 220
Chapter 36: Drugs For Bipolar Disorder ................................................................................................ 230
Chapter 37: Sedative-Hypnotic Drugs ....................................................................................................237
Chapter 38: Management Of Anxiety Disorders .................................................................................. 246
Chapter 39: Central Nervous System Stimulants And Attention-Deficit/Hyperactivity Disorder
......................................................................................................................................................................... 252
Chapter 40: Substance Use Disorders I: Basic Considerations ........................................................... 258
Chapter 41: Substance Use Disorders Ii: Alcohol ................................................................................... 263
Chapter 42: Substance Use Disorders Iii: Nicotine .................................................................................273
Chapter 43: Substance Use Disorders Iv: Major Drugs Of Abuse Other Than Alcohol And
Nicotine .......................................................................................................................................................... 279
Chapter 44: Diuretics ...................................................................................................................................288
Chapter 45: Agents Affecting The Volume And Ion Content Of Body Fluids ............................... 294
Chapter 46: Review Of Hemodynamics ................................................................................................ 302
Chapter 47: Drugs Acting On The Renin-Angiotensin-Aldosterone System.................................. 306
Chapter 48: Calcium Channel Blockers ................................................................................................... 312
Chapter 49: Vasodilators ............................................................................................................................ 316
Chapter 50: Drugs For Hypertension...................................................................................................... 322
Chapter 51: Drugs For Heart Failure....................................................................................................... 332
Chapter 52: Antidysrhythmic Drugs ........................................................................................................ 343
Chapter 53: Drugs That Help Normalize Cholesterol And Triglyceride Levels ............................. 354
Chapter 54: Drugs For Angina Pectoris ................................................................................................. 364
Chapter 55: Anticoagulant, Antiplatelet, And Thrombolytic Drugs ................................................373
Chapter 56: Management Of St-Elevation Myocardial Infarction ..................................................383
Chapter 57: Drugs For Hemophilia ......................................................................................................... 389
Chapter 58: Drugs For Deficiency Anemias ........................................................................................... 396
Chapter 59: Hematopoietic Agents ........................................................................................................404
Chapter 60: Drugs For Diabetes Mellitus ...............................................................................................410
,Chapter 61: Drugs For Thyroid Disorders ................................................................................................ 419
Chapter 62: Drugs Related To Hypothalamic And Pituitary Function ......................................... 427
Chapter 63: Drugs For Disorders Of The Adrenal Cortex .................................................................. 434
Chapter 64: Estrogens And Progestins: Basic Pharmacology And Noncontraceptive
Applications .................................................................................................................................................. 439
Chapter 65: Birth Control .......................................................................................................................... 445
Chapter 66: Drug Therapy For Infertility .............................................................................................. 454
Chapter 67: Drugs That Affect Uterine Function .................................................................................460
Chapter 68: Androgens .............................................................................................................................. 466
Chapter 69: Drugs For Erectile Dysfunction And Benign Prostatic Hyperplasia ......................... 473
Chapter 70: Review Of The Immune System ....................................................................................... 479
Chapter 71: Childhood Immunization ..................................................................................................... 485
Chapter 72: Immunosuppressants ........................................................................................................... 493
Chapter 73: Antihistamines ....................................................................................................................... 499
Chapter 74: Cyclooxygenase Inhibitors, Nonsteroidal Anti-Inflammatory Drugs And
Acetaminophen ........................................................................................................................................... 507
Chapter 75: Glucocorticoids In Nonendocrine Disorders ..................................................................... 515
Chapter 76: Drug Therapy For Rheumatoid Arthritis ........................................................................ 523
Chapter 77: Drug Therapy For Gout .......................................................................................................527
Chapter 78: Drugs Affecting Calcium Levels And Bone Mineralization ......................................... 532
Chapter 79: Drugs For Asthma And Chronic Obstructive Pulmonary Disease ............................ 542
Chapter 80: Drugs For Allergic Rhinitis, Cough, And Colds ............................................................... 553
Chapter 81: Drugs For Peptic Ulcer Disease .......................................................................................... 560
Chapter 82: Laxatives ................................................................................................................................. 568
Chapter 83: Other Gastrointestinal Drugs ............................................................................................. 576
Chapter 84: Vitamins ...................................................................................................................................587
Chapter 85: Drugs For Weight Loss ......................................................................................................... 595
Chapter 86: Complementary And Alternative Therapy ...................................................................602
Chapter 87: Basic Principles Of Antimicrobial Therapy ..................................................................... 608
Chapter 88: Drugs That Weaken The Bacterial Cell Wall I: Penicillins ............................................ 615
Chapter 89: Drugs That Weaken The Bacterial Cell Wall Ii: Other Drugs ..................................... 624
Chapter 90: Bacteriostatic Inhibitors Of Protein Synthesis: Tetracyclines, Macrolides, And Others
......................................................................................................................................................................... 630
,Chapter 91: Aminoglycosides: Bactericidal Inhibitors Of Protein Synthesis .................................... 642
Chapter 92: Sulfonamides And Trimethoprim ...................................................................................... 651
Chapter 93: Drug Therapy For Urinary Tract Infections .................................................................... 657
Chapter 94: Antimycobacterial Agents ................................................................................................. 666
Chapter 95: Miscellaneous Antibacterial Drugs ....................................................................................677
Chapter 96: Antifungal Agents ................................................................................................................ 683
Chapter 97: Antiviral Agents I: Drugs For Non-Hiv Viral Infections ................................................ 694
Chapter 98: Antiviral Agents Ii: Drugs For Hiv Infection And Related Opportunistic Infections
......................................................................................................................................................................... 702
Chapter 99: Drug Therapy For Sexually Transmitted Diseases ......................................................... 710
Chapter 100: Antiseptics And Disinfectants ........................................................................................... 716
Chapter 101: Anthelmintics ......................................................................................................................... 721
Chapter 102: Antiprotozoal Drugs I: Antimalarial Agents ................................................................ 726
Chapter 103: Antiprotozoal Drugs Ii: Miscellaneous Agents ...............................................................732
Chapter 104: Ectoparasiticides ..................................................................................................................735
Chapter 105: Basic Principles Of Cancer Chemotherapy ................................................................... 742
Chapter 106: Anticancer Drugs I: Cytotoxic Agents.............................................................................. 751
Chapter 107: Anticancer Drugs Ii: Noncytotoxic Agents ..................................................................... 760
Chapter 108: Drugs For The Eye .............................................................................................................. 766
Chapter 109: Drugs For The Skin .............................................................................................................. 773
Chapter 110: Drugs For The Ear.................................................................................................................784
Chapter 111: Management Of Poisoning ................................................................................................. 791
Chapter 112: Potential Weapons Of Biologic, Radiologic, And Chemical Terrorism .....................797
,Chapter 01: Orientation To Pharmacology
Burchum: Lehne’s Pharmacology For Nursing Care, 11th Edition
Multiple Choice
1. The Nurse Is Teaching A Patient How A Medication Works To Treat An Illness. To Do This,
The Nurse Will Rely On Knowledge Of Which Topic?
A. Clinical Pharmacology
B. Drug Efficacy
C. Pharmacokinetics
D. Pharmacotherapeutics
Answer: D
Pharmacotherapeutics Is The Study Of The Use Of Drugs To Diagnose, Treat, And Prevent
Conditions. Clinical Pharmacology Is Concerned With All Aspects Of Drug-Human Interactions.
Drug Efficacy Measures The Extent To Which A Given Drug Causes An Intended Effect.
Pharmacokinetics Is The Study Of The Impact Of The Body On A Drug.
Pts: 1
2. What Is A Desired Outcome When A Drug Is Described As Easy To Administer?
A. It Can Be Stored Indefinitely Without Need For Refrigeration.
B. It Does Not Interact Significantly With Other Medications.
C. It Enhances Patient Adherence To The Drug Regimen.
D. It Is Usually Relatively Inexpensive To Produce.
Answer: C
A Major Benefit Of Drugs That Are Easy To Administer Is That Patients Taking Them Are More
Likely To Comply With The Drug Regimen. Drugs That Are Easy To Give May Have The Other
Attributes Listed, But Those Properties Are Independent Of Ease Of Administration.
Pts: 1
,3. A Patient Tells The Nurse That An Analgesic He Will Begin Taking May Cause Drowsiness
And Will Decrease Pain Up To 4 Hours At A Time. Based On This Understanding Of The Drug’s
Effects By The Patient, The Nurse Will Anticipate Which Outcome?
A. Decreased Chance Of Having A Placebo Effect
B. Decreased Motivation To Take The Drug
C. Improved Compliance With The Drug Regimen
D. Increased Likelihood Of Drug Overdose
Answer: C
A Drug Is Effective If It Produces The Intended Effects, Even If It Also Produces Side Effects.
Patients Who Understand Both The Risks And Benefits Of Taking A Medication Are More Likely
To Comply With The Drug Regimen.
Pts: 1
Multiple Response
1. What Are Considered The ‘Big Three’ Properties Of An Ideal Drug? (Select All That
Apply.)
A. Irreversible Action
B. Effectiveness
C. Safety
D. Selectivity
E. A Recognizable Trade Name
Answer: B, C, D
The ‘Big Three’ Properties Of The Ideal Drug Are Effectiveness, Safety, And Selectivity. Pts: 1
,2. Before Administering A Medication, What Does The Nurse Need To Know To Evaluate
How Individual Patient Variability Might Affect The Patient’s Response To The Medication?
(Select All That Apply.)
A. Chemical Stability Of The Medication
B. Ease Of Administration
C. Family Medical History
D. Patient’s Age
E. Patient’s Diagnosis
Answer: C, D, E
The Family Medical History Can Indicate Genetic Factors That May Affect A Patient’s Response
To A Medication. Patients Of Different Ages Can Respond Differently To Medications. The
Patient’s Illness Can Affect How Drugs Are Metabolized. The Chemical Stability Of The
Medication And The Ease Of Administration Are Properties Of Drugs.
Pts: 1
Chapter 02: Application Of Pharmacology In Nursing
Practice
Burchum: Lehne’s Pharmacology For Nursing Care, 11th Edition
Multiple Choice
1. A Patient Is Using A Metered-Dose Inhaler Containing Albuterol For Asthma. The
Medication Label Instructs The Patient To Administer “2 Puffs Every 4 Hours As Needed For
Coughing Or Wheezing.” The Patient Reports Feeling Jittery Sometimes When Taking The
Medication, And Doesn’t Feel That The Medication Is Always Effective. Which Action Is Outside
The Nurse’s Scope Of Practice?
A. Asking The Patient To Demonstrate The Use Of The Inhaler
B. Assessing The Patient’s Exposure To Tobacco Smoke
,C. Auscultating Lung Sounds And Obtaining Vital Signs
D. Suggesting That The Patient Use 1 Puff To Reduce Side Effects
Answer: D
It Is Not Within The Nurse’s Scope Of Practice To Change The Dose Of A Medication Without An
Order From A Prescriber. Asking The Patient To Demonstrate Inhaler Use Helps The Nurse To
Evaluate The Patient’s Ability To Administer The Medication Properly And Is Part Of The Nurse’s
Evaluation.
Assessing Tobacco Smoke Exposure Helps The Nurse Determine Whether Nondrug Therapies,
Such A Smoke Avoidance, Can Be Used As An Adjunct To Drug Therapy. Performing A Physical
Assessment Helps The Nurse Evaluate The Patient’s Response To The Medication.
Pts: 1
2. A Postoperative Patient Is Being Discharged Home With Acetaminophen/Hydrocodone
[Norco] For Pain. The Patient Asks The Nurse About Using Tylenol For Fever. Which Statement By
The Nurse Is Correct?
A. “It Is Not Safe To Take Over-The-Counter Drugs With Prescription Medications.”
B. “Taking The Two Medications Together Poses A Risk Of Drug Toxicity.”
C. “There Are No Known Drug Interactions, So This Will Be Safe.”
D. “Tylenol And Norco Are Different Drugs, So There Is No Risk Of Overdose.”
Answer: B
Tylenol Is The Trade Name And Acetaminophen Is The Generic Name For The Same Medication.
It Is Important To Teach Patients To Be Aware Of The Different Names For The Same Drug To
Minimize The Risk Of Overdose. Over-The-Counter (Otc) Medications And Prescription
Medications May Be Taken Together Unless Significant Harmful Drug Interactions Are Possible.
Even Though No Drug Interactions Are At Play In This Case, Both Drugs Contain Acetaminophen,
Which Could Lead To Toxicity.
Pts: 1
, 3. The Nurse Is Preparing To Care For A Patient Who Will Be Taking An Antihypertensive
Medication. Which Action By The Nurse Is Part Of The Assessment Step Of The Nursing Process?
A. Asking The Prescriber For An Order To Monitor Serum Drug Levels
B. Monitoring The Patient For Drug Interactions After Giving The Medication
C. Questioning The Patient About Over-The-Counter Medications
D. Taking The Patient’s Blood Pressure Throughout The Course Of Treatment
Answer: C
The Assessment Part Of The Nursing Process Involves Gathering Information Before Beginning
Treatment, And This Includes Asking About Other Medications The Patient May Be Taking.
Monitoring Serum Drug Levels, Watching For Drug Interactions, And Checking Vital Signs After
Giving The Medication Are All Part Of The Evaluation Phase.
Pts: 1
4. A Postoperative Patient Reports Pain, Which The Patient Rates As An 8 On A Scale From
1 To 10 (10 Being The Most Extreme Pain). The Prescriber Has Ordered Acetaminophen [Tylenol]
650 Mg Po Every 6 Hours Prn Pain. What Will The Nurse Do?
A. Ask The Patient What Medications Have Helped With Pain In The Past.
B. Contact The Provider To Request A Different Analgesic Medication.
C. Give The Pain Medication And Reposition The Patient To Promote Comfort.
D. Request An Order To Administer The Medication Every 4 Hours.
Answer: B
The Nursing Diagnosis For This Patient Is Severe Pain. Acetaminophen Is Given For Mild To
Moderate Pain, So The Nurse Should Ask The Prescriber To Order A Stronger Analgesic
Medication. Asking The Patient To Tell The Nurse What Has Helped In The Past Is Part Of An
Initial Assessment And Should Be Done Preoperatively And Not When The Patient Is Having
Severe Pain. Because The Patient Is Having Severe Pain, Acetaminophen Combined With
Nondrug Therapies Will Not Be Sufficient. Increasing The Frequency Of The Dose Of A
Medication For Mild Pain Will Not Be Effective.
