NR 293 Pharm Exam 1 Chamberlain 2025
Risks for injury - Correct Ans-know that anything can be a possible risk for patient injury
9 rights of medicine administration - Correct Ans-right patient, right dose, right
medication, right time, right documentation, right route, right reason, right response
what is a prototype - Correct Ans-the first drug of a class that all others are based from
(ex- morphine)
what is pharmacokinetics - Correct Ans-what the body does to the drug
what is pharmacodynamics - Correct Ans-what the drug does to the body
bioavailability - Correct Ans-what portion of the drug that entered the circulation can
have an effect on the body
first pass effect - Correct Ans-a drug enters the GI tract and is filtered to the liver where
some is destroyed
what enzymes work in the liver - Correct Ans-P-450 enzymes
if a patient has cirrhosis of the liver, what will happen when they take a medication? -
Correct Ans-When the medication passes through the liver for the first pass, there will
be less P-450 enzymes so the bioavailability of the medication will be higher and it will
circulate in the bloodstream longer.
half life - Correct Ans-time required for 50% of the drug to be removed from the body
Pharmacotherapeutics - Correct Ans-treatment of conditions
enteral route - Correct Ans-through the GI tract
parenteral tract - Correct Ans-outside the GI tract
how is medication absorption different for neonates and children? - Correct Ans-they
have less gastric acid to break down medications and availability is higher
why do more drugs enter neonate and children's brains, why are meds not as easily
excreted/destroyed by liver and kidneys ? - Correct Ans-immature BBB, liver, and
kidneys
Polypharmacy - Correct Ans-The use of multiple medications on a regular basis
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during which phase of the nursing process does a nurse prioritize the nursing
diagnoses? - Correct Ans-planning
the nurse recognizes that drugs given by which route will be altered by the first pass
effect?
a. oral
b. sublingual
c. subcutaneous
d. IV
e. rectal - Correct Ans-oral and rectal
the nurse is reviewing a list of a patient's medications and notes one of the drugs has a
low therapeutic index. what does this mean? - Correct Ans-the difference between a
therapeutic dose and a toxic dose are very close together
when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of
drug B? - Correct Ans-level of drug B could rise to toxicity
A drug is highly protein bound, what does this mean? - Correct Ans-it will have a longer
duration of action
do no harm is what ethical principle? - Correct Ans-nonmaleficence
Which legal act required drug manufacturers to establish the safety and efficacy of a
new drug before its approval for use? - Correct Ans-Kefauver-Harris, amendment of
1962
over the counter drugs (otc) are - Correct Ans-nonprescription drugs that are used for
short term treatment
what herbal supplement is used to promote sleep and relaxation, prolonged use can
cause yellow discoloration of nails, risk for liver toxicity - Correct Ans-kava
herbal supplement used to decrease nausea and vomiting induced by chemotherapy -
Correct Ans-ginkgo
which drug classes are used as OTC remedies ?
a. NSAIDs
b. cold remedies
c. antibiotics
d.smoking deterrent drugs
e. antihypertensive drugs
f. histamine 2 (H2) blockers - Correct Ans-A, B,D,F
what are side effects of NSAIDs? - Correct Ans-stroke, MI, GI ulcers, kidney dysfunction
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what do antibiotics do? - Correct Ans-fight off infection caused by bacteria
Bacteriostatic - Correct Ans-doesn't kill bacteria, it inhibits growth
bactericidal - Correct Ans-kills bacteria
healthcare associated infections - Correct Ans-are contracted in a hospital or institution
(>48 hours after admin) , are more difficult to treat, and are more virulent
antiseptics - Correct Ans-are used for living tissue, inhibit growth of bacteria
disinfectants - Correct Ans-used on nonliving tissue, destroy/kill organisms
what is a priority of the nurse to perform before beginning an antibiotic therapy? -
Correct Ans-obtain a culture and sensitivity specimen
prophylactic therapy - Correct Ans-preventative measure, antibiotics given before a
procedure to ensure that an infection will not start
empiric therapy - Correct Ans-treatment of an infection before c+s information has been
obtained or reported
definitive therapy - Correct Ans-treatment of a specific infection after receiving repot of
c+s
what two classes of antibiotics are common for causing allergic reactions? - Correct
Ans-penicillins and sulfonamides
if a person is allergic to penicillin, what other class of antibiotics should be looked into? -
Correct Ans-cephalosporins
what is the main example of sulfonamides? - Correct Ans-Bactrim
what must Bactrim be taken with? - Correct Ans-2000-3000 mL of H20/ day
what is the MOA of sulfonamides ? - Correct Ans-bacteriostatic
Indications for sulfonamides - Correct Ans-broad spectrum, gram + or -; UTIs
adverse effects of sulfonamides - Correct Ans-SJS, photosensitivity
contraindications of sulfonamides - Correct Ans-allergy, pregnancy
what are the main examples of Beta Lactams- penicillins - Correct Ans-amoxicillin,
ampicillin
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