Primary Engineering Controls and Laminar Airflow Systems

Primary Engineering Controls and
Laminar Airflow Systems

PEC should be turned off when not in use to reduce wear and maintenance of
HEPA filter
False

Should always be operational

If turned off needs to runs for at least 30 minutes before compounding
Laminar Airflow Workbench
(LAFW)

1) Describe how air gets filtered

2) Is flow horizontal or vertical

3) Can be use for HD Compounding?
Laminar Airflow Workbench
(LAFW)

1) Room air -> filter -> HEPA filter -> work zone

2) Horizontal most common but can be either

3) No HD. No environmental or personal controls




Describe the zone of turbulence
Area behind any item (e.g., vial, IV bag, syringe) on the hood where sterile
airflow from the HEPA filter is interrupted; the zone or area is thereby
contaminated; sterile parenteral products should not be prepared within a
zone of turbulence

, Laminar Airflow Zone (LAFZ)

1) Commonly also know as what

2) Describe airflow

3) Vertical or horizontal airflow

4) Can be used for HD compounding?
Laminar Airflow Zone (LAFZ)

1) Open architecture cleanroom

2) Air is filtered by ceiling mounted fan filters. Moves in downward motion
then air cascades over sides of table and then into air returns

3) Vertical

4) NO, No environmental controls
Laminar Airflow Zone (LAFZ)

1) How is PEC zone created since there is not a cabinet

2) Can this be used for category 2 compounding
Laminar Airflow Zone (LAFZ)

1) Containment curtain

2) Yes if they are certified




Biological Safety Cabinet (BSC)

1) What type of compounding is typically done in this cabinet

2) Vertical or horizontal airflow

3) When is air HEPA filtered

4) What are the different types of BSC