Solutions
Naltrexone forms and dosing pill and injection available
must take 50mg x7d before getting shot; no opioids in last 7d before starting
naltrexone MOA and side effects MOA: opioid antagonoist; blocks euphoric effects of
alcohol and prevents craving
SE: withdrawal, nausea, dizzy, anxiety, fatigue
paroxetine; use tx of choice in PTSD veterans, sexual trauma
paroxetine side effects sedation, weight gain, sexual, anticholinergic
paroxetine dosing 10-20mg/d and increase by 10-20mg every 2 weeks to max of 60
prazosin; MOA, use for nightmares due to PTSD, blocks norepinephrine
, prazosin; dosing, monitor fo dosing: 1-15mg; start with 1mg
monitor: blood pressure and pulse
sertraline: dosing start at 25-50mg x1wk and increase by 25-50 every 1-2wks to max of
200
sertraline side effects nausea, decreased appetite, sleepiness, tremors, sweating, insomnia,
sexual
alcohol intoxication s/sx recent ingestion
at least one of: slurred speech, incoordination, unsteady gait, nystagmus, memory impaired,
stupor or coma
alcoholic cirrhosis fatigue, weakness, weight loss, GI bleed, abdominal swelling,
concussion, jaundice
liver has scar tissue
liver transplant needed
alcoholic liver disease fatty liver, alcoholic hepatitis, cirrhosis