,This page intentionally left blank.
A A A A A
, 100 C ASE STU DI ES
A A A A A A
I N PATHOP HYSIOLOGY
A A A
Harold J. Bruyere, Jr., Ph.D.
A A A A
PROFESSORAEMERITUS
UNIVERSITYAOFAWYOMING
LARAMIE,AWYOMING
AcquisitionsAEditor:ADavidATroy
ManagingAEditor:AMeredithAL.ABrittain
MarketingAManager:AAllisonAM.ANoplock
AssociateAProductionAManager:AKevinAP.AJohnsonA
Designer:ATeresaAMallon
Compositor:AInternationalATypesettingAandAComposition
CopyrightA©A2009ALippincottAWilliamsA&AWilkins,AaAWoltersAKluwerAbusiness.
351AWestACamdenAStreet 530AWalnutAStreet
Baltimore,AMDA21201A Philadelphia,APAA19106
PrintedAinAtheAUnitedAStatesAofAAmerica
AllArightsAreserved.AThisAbookAisAprotectedAbyAcopyright.ANoApartAofAthisAbookAmayAbeAreproducedAorAtransmittedAinAa
nyAformAorAbyAanyAmeans,AincludingAasAphotocopiesAorAscanned-
inAorAotherAelectronicAcopies,AorAutilizedAbyAanyAinformationAstorageAandAretrievalAsystemAwithoutAwrittenApermissionAfr
, omAtheAcopyrightAowner,AexceptAforAbriefAquotationsAembodiedAinAcriticalAarticlesAandAreviews.AMaterialsAappearingAinA
thisAbookApreparedAbyAindividualsAasApartAofAtheirAofficialAdutiesAasAU.S.AgovernmentAemployeesAareAnotAcoveredAbyAth
eAabove-
mentionedAcopyright.AToArequestApermission,ApleaseAcontactALippincottAWilliamsA&AWilkinsAatA530AWalnutAStreet,APhil
adelphia,APAA19106,,AorAviaAwebsiteAatAlww.comA(productsAandAservices).
9AAA8AAA7AAA6AAA5AAA4AAA3AAA2AAA1
LibraryAofACongressACataloging-in-PublicationAData
Bruyere,AHaroldAJoseph,A1947-
100AcaseAstudiesAinApathophysiologyA/AHaroldAJ.ABruyereAJr.
p.A;Acm.
ISBNA978-0-7817-6145-1
1.APhysiology,APathological—
CaseAstudies.AI.ATitle.AII.ATitle:AOneAhundredAcaseAstudiesAinApathophysiology.
[DNLM: 1.APathology—CaseAReports. 2.AClinicalAMedicine—CaseAReports.
3.APhysiology—CaseAReports. WBA293AB914zA2009]
RB113.B79A2009
616.07—dc22
2008014719
DISCLAIMER
CareAhasAbeenAtakenAtoAconfirmAtheAaccuracyAofAtheAinformationApresentAandAtoAdescribeAgenerallyAacceptedApractic
es.AHowever,AtheAauthors,Aeditors,AandApublisherAareAnotAresponsibleAforAerrorsAorAomissionsAorAforAanyAconsequencesAf
romAapplicationAofAtheAinformationAinAthisAbookAandAmakeAnoAwarranty,AexpressedAorAimplied,AwithArespectAtoAtheAcurr
ency,Acompleteness,AorAaccuracyAofAtheAcontentsAofAtheApublication.AApplicationAofAthisAinformationAinAaAparticularAsitu
ationAremainsAtheAprofessionalAresponsibilityAofAtheApractitioner;AtheAclinicalAtreatmentsAdescribedAandArecommendedAma
yAnotAbeAconsideredAabsoluteAandAuniversalArecommendations.
TheAauthors,Aeditors,AandApublisherAhaveAexertedAeveryAeffortAtoAensureAthatAdrugAselectionAandAdosageAsetAforthAinA
thisAtextAareAinAaccordanceAwithAtheAcurrentArecommendationsAandApracticeAatAtheAtimeAofApublication.AHowever,AinAvie
wAofAongoingAresearch,AchangesAinAgovernmentAregulations,AandAtheAconstantAflowAofAinformationArelatingAtoAdrugAthera
pyAandAdrugAreactions,AtheAreaderAisAurgedAtoAcheckAtheApackageAinsertAforAeachAdrugAforAanyAchangeAinAindicationsAan
dAdosageAandAforAaddedAwarningsAandAprecautions.AThisAisAparticularlyAimportantAwhenAtheArecommendedAagentAisAaAne
wAorAinfrequentlyAemployedAdrug.
SomeAdrugsAandAmedicalAdevicesApresentedAinAthisApublicationAhaveAFoodAandADrugAAdministrationA(FDA)Aclearanc
eAforAlimitedAuseAinArestrictedAresearchAsettings.AItAisAtheAresponsibilityAofAtheAhealthAcareAproviderAtoAascertainAtheAFD
AAstatusAofAeachAdrugAorAdeviceAplannedAforAuseAinAtheirAclinicalApractice.
ToApurchaseAadditionalAcopiesAofAthisAbook,AcallAourAcustomerAserviceAdepartmentAatA(800)A638-
3030AorAfaxAordersAtoA(301)A223-2320.AInternationalAcustomersAshouldAcallA(301)A223-2300.
VisitALippincottAWilliamsA&AWilkinsAonAtheAInternet:Ahttp://www.lww.com.ALippincottAWilliamsA&AWilkinsAcustomerAs
erviceArepresentativesAareAavailableAfromA8:30AamAtoA6:00Apm,AEST.
Dedication
ThisAcaseAstudiesAworkbookAisAdedicatedAtoAmyAbelovedAwife,AKathy,AmyAson,
Travis,AandAmyAdaughter,AKimberly,AwhoAhaveAbeenAanAinspirationAtoAmeAandAwhom
AIAloveAveryAmuch.
CaseAStudyA32AisAdedicatedAtoAmyAfriend,AMerrillABuckley,AwhoApassedAawayAonAJulyA6,A20
07AafterAaAlongAandAcourageousAbattleAwithAchronicArenalAfailure.
CaseAStudyA45AisAdedicatedAtoAmyAlateAfriend,AEddieAAlwin,AwhoAstruggledAwithAParki
nsonAdiseaseAforAmanyAyears.
CaseAStudyA49AisAdedicatedAtoAmyAfather,AwhoApassedAawayAinAJulyA1993AafterAaAlongA
andAcourageousAbattleAwithAdepression.
A A A A A
, 100 C ASE STU DI ES
A A A A A A
I N PATHOP HYSIOLOGY
A A A
Harold J. Bruyere, Jr., Ph.D.
A A A A
PROFESSORAEMERITUS
UNIVERSITYAOFAWYOMING
LARAMIE,AWYOMING
AcquisitionsAEditor:ADavidATroy
ManagingAEditor:AMeredithAL.ABrittain
MarketingAManager:AAllisonAM.ANoplock
AssociateAProductionAManager:AKevinAP.AJohnsonA
Designer:ATeresaAMallon
Compositor:AInternationalATypesettingAandAComposition
CopyrightA©A2009ALippincottAWilliamsA&AWilkins,AaAWoltersAKluwerAbusiness.
351AWestACamdenAStreet 530AWalnutAStreet
Baltimore,AMDA21201A Philadelphia,APAA19106
PrintedAinAtheAUnitedAStatesAofAAmerica
AllArightsAreserved.AThisAbookAisAprotectedAbyAcopyright.ANoApartAofAthisAbookAmayAbeAreproducedAorAtransmittedAinAa
nyAformAorAbyAanyAmeans,AincludingAasAphotocopiesAorAscanned-
inAorAotherAelectronicAcopies,AorAutilizedAbyAanyAinformationAstorageAandAretrievalAsystemAwithoutAwrittenApermissionAfr
, omAtheAcopyrightAowner,AexceptAforAbriefAquotationsAembodiedAinAcriticalAarticlesAandAreviews.AMaterialsAappearingAinA
thisAbookApreparedAbyAindividualsAasApartAofAtheirAofficialAdutiesAasAU.S.AgovernmentAemployeesAareAnotAcoveredAbyAth
eAabove-
mentionedAcopyright.AToArequestApermission,ApleaseAcontactALippincottAWilliamsA&AWilkinsAatA530AWalnutAStreet,APhil
adelphia,APAA19106,,AorAviaAwebsiteAatAlww.comA(productsAandAservices).
9AAA8AAA7AAA6AAA5AAA4AAA3AAA2AAA1
LibraryAofACongressACataloging-in-PublicationAData
Bruyere,AHaroldAJoseph,A1947-
100AcaseAstudiesAinApathophysiologyA/AHaroldAJ.ABruyereAJr.
p.A;Acm.
ISBNA978-0-7817-6145-1
1.APhysiology,APathological—
CaseAstudies.AI.ATitle.AII.ATitle:AOneAhundredAcaseAstudiesAinApathophysiology.
[DNLM: 1.APathology—CaseAReports. 2.AClinicalAMedicine—CaseAReports.
3.APhysiology—CaseAReports. WBA293AB914zA2009]
RB113.B79A2009
616.07—dc22
2008014719
DISCLAIMER
CareAhasAbeenAtakenAtoAconfirmAtheAaccuracyAofAtheAinformationApresentAandAtoAdescribeAgenerallyAacceptedApractic
es.AHowever,AtheAauthors,Aeditors,AandApublisherAareAnotAresponsibleAforAerrorsAorAomissionsAorAforAanyAconsequencesAf
romAapplicationAofAtheAinformationAinAthisAbookAandAmakeAnoAwarranty,AexpressedAorAimplied,AwithArespectAtoAtheAcurr
ency,Acompleteness,AorAaccuracyAofAtheAcontentsAofAtheApublication.AApplicationAofAthisAinformationAinAaAparticularAsitu
ationAremainsAtheAprofessionalAresponsibilityAofAtheApractitioner;AtheAclinicalAtreatmentsAdescribedAandArecommendedAma
yAnotAbeAconsideredAabsoluteAandAuniversalArecommendations.
TheAauthors,Aeditors,AandApublisherAhaveAexertedAeveryAeffortAtoAensureAthatAdrugAselectionAandAdosageAsetAforthAinA
thisAtextAareAinAaccordanceAwithAtheAcurrentArecommendationsAandApracticeAatAtheAtimeAofApublication.AHowever,AinAvie
wAofAongoingAresearch,AchangesAinAgovernmentAregulations,AandAtheAconstantAflowAofAinformationArelatingAtoAdrugAthera
pyAandAdrugAreactions,AtheAreaderAisAurgedAtoAcheckAtheApackageAinsertAforAeachAdrugAforAanyAchangeAinAindicationsAan
dAdosageAandAforAaddedAwarningsAandAprecautions.AThisAisAparticularlyAimportantAwhenAtheArecommendedAagentAisAaAne
wAorAinfrequentlyAemployedAdrug.
SomeAdrugsAandAmedicalAdevicesApresentedAinAthisApublicationAhaveAFoodAandADrugAAdministrationA(FDA)Aclearanc
eAforAlimitedAuseAinArestrictedAresearchAsettings.AItAisAtheAresponsibilityAofAtheAhealthAcareAproviderAtoAascertainAtheAFD
AAstatusAofAeachAdrugAorAdeviceAplannedAforAuseAinAtheirAclinicalApractice.
ToApurchaseAadditionalAcopiesAofAthisAbook,AcallAourAcustomerAserviceAdepartmentAatA(800)A638-
3030AorAfaxAordersAtoA(301)A223-2320.AInternationalAcustomersAshouldAcallA(301)A223-2300.
VisitALippincottAWilliamsA&AWilkinsAonAtheAInternet:Ahttp://www.lww.com.ALippincottAWilliamsA&AWilkinsAcustomerAs
erviceArepresentativesAareAavailableAfromA8:30AamAtoA6:00Apm,AEST.
Dedication
ThisAcaseAstudiesAworkbookAisAdedicatedAtoAmyAbelovedAwife,AKathy,AmyAson,
Travis,AandAmyAdaughter,AKimberly,AwhoAhaveAbeenAanAinspirationAtoAmeAandAwhom
AIAloveAveryAmuch.
CaseAStudyA32AisAdedicatedAtoAmyAfriend,AMerrillABuckley,AwhoApassedAawayAonAJulyA6,A20
07AafterAaAlongAandAcourageousAbattleAwithAchronicArenalAfailure.
CaseAStudyA45AisAdedicatedAtoAmyAlateAfriend,AEddieAAlwin,AwhoAstruggledAwithAParki
nsonAdiseaseAforAmanyAyears.
CaseAStudyA49AisAdedicatedAtoAmyAfather,AwhoApassedAawayAinAJulyA1993AafterAaAlongA
andAcourageousAbattleAwithAdepression.
