COMPLETE TEST BANK FOR Pathophysiology: The Biologic Basis for Disease in Adults and Children 8th Edition by Kathryn L. McCance MS PhD (Author) latest update

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McCance: Pathophysiology: The Biology Basis or Disease in Adults and Children (8th Edition) TEST BANK

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McCance: Pathophysiology: The Biology Basis or Disease in Adults and Children (8th Edition) TEST BANK

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McCance: Pathophysiology: The Biology Basis or Disease in Adults and Children (8th Edition) TEST BANK


Part 1: CENTRAL CONCEPTS O PATHOPHYSIOLOGY: CELLS AND TISSUES
Unit 1: THE CELL


CHAPTER 01: CELLULAR BIOLOGY

MULTIPLE CHOICE

1. Whichustatementubestudescribesutheucellularufunctionuofumetabolicuabsorption?
a. Cellsucanuproduceuproteins.
b. Cellsucanusecreteudigestiveuenzymes
.
c. Cellsucanutakeuinuanduuseunutrients.
d. Cellsucanusynthesizeufats.
ANS:u C
Inumetabolicuabsorption,uallucellsutakeuinuanduuseunutrientsuanduotherusubstancesufromutheirusurroun
dings.uTheuremaininguoptionsuareunotuinclusiveuinutheirudescriptionsuofucellularumetabolicuabsorptio
n.

PTS:u u 1 DIF: CognitiveuLevel:uRemembering

2. Whereuisumostuofuaucell’sugeneticuinformation,uincludinguRNAuanduDNA,ucontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS:u C
Theunucleusucontainsutheunucleolus,uausmalludenseustructureucomposedulargelyuofuRNA,umostu
ofutheucellularuDNA,uandutheuDNA-
bindinguproteins,usuchuasutheuhistones,uwhichuregulateuitsuactivity.uTheumitochondriauareurespo
nsibleuforucellularurespirationuanduenergyuproduction.
Ribosomes’uchiefufunctionuisutouprovideusitesuforucellularuproteinusynthesis.uLysosomesufunctio
nuasutheuintracellularudigestiveusystem.

PTS:u u 1 DIF: CognitiveuLevel:uRemembering

3. Whichucomponentuofutheucelluproducesuhydrogenuperoxideu(H2O2)ubyuusinguoxygenutouremo
veuhydrogenuatomsufromuspecificusubstratesuinuanuoxidativeureaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome

ANS:u B

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McCance: Pathophysiology: The Biology Basis or Disease in Adults and Children (8th Edition) TEST BANK



Peroxisomesuareusounamedubecauseutheyuusuallyucontainuenzymesuthatuuseuoxygenutouremoveuhydr
ogenuatomsufromuspecificusubstratesuinuanuoxidativeureactionuthatuproducesuH2O2,uwhichuisuaupower
fuluoxidantuandupotentiallyudestructiveuifuituaccumulatesuoruescapesufromuperoxisomes.
RibosomesuareuRNA-
proteinucomplexesu(nucleoproteins)uthatuareusynthesizeduinutheunucleolusuandusecreteduintouthe
ucytoplasmuthroughuporesuinutheunuclearuenvelopeucalledunuclearuporeucomplexes.uLysosomesu
areusaclikeustructuresuthatuoriginateufromutheuGolgiucomplexuanducontainumoreuthanu40udigestiv
euenzymesucalleduhydrolases,uwhichucatalyzeubondsuinuproteins,ulipids,unucleicuacids,uanducarb
ohydrates.uAnuendosomeuisuauvesicaluthatuhasubeenupincheduoffufromutheucellularumembrane.

PTS:u u 1 DIF: CognitiveuLevel:uRemembering

4. Whichucellucomponentuisucapableuofucellularuautodigestionuwhenuituisureleaseduduringucelluinjury?
a. Ribosome
b. Golgiucomplex
c. Smoothuendoplasmicureticulum
d. Lysosomes
ANS:u D
Theulysosomalumembraneuactsuasuauprotectiveushieldubetweenutheupowerfuludigestiveuenzymesu
withinutheulysosomeuandutheucytoplasm,upreventingutheiruleakageuintoutheucytoplasmicumatrix.u
Disruptionuofutheumembraneubyuvariousutreatmentsuorucellularuinjuryuleadsutouaureleaseuofutheul
ysosomaluenzymes,uwhichucanuthenureactuwithutheiruspecificusubstrates,ucausingucellularuself-
udigestion.uTheuchiefufunctionuofuauribosomeuisutouprovideusitesuforucellularuproteinusynthesis.u
TheuGolgiucomplexuisuaunetworkuofuflattened,usmoothuvesiclesuandumembranesuoftenulocatedun
earutheucellunucleus.uTheusmoothuendoplasmicureticulumuisuinvolveduinusteroiduhormoneuprodu
ctionuanduremovingutoxicusubstancesufromutheucell.

PTS:u u 1 DIF: CognitiveuLevel:uRemembering

5. WhichucAMP-mediateduresponseuisurelatedutouantidiureticuhormone?
a. Increaseduhearturateuanduforceuofucontractio
n
b. Secretionuofucortisol
c. Increaseduretentionuofuwater
d. Breakdownuofufat
ANS:u C
Antidiureticuhormoneuleadsutouincreaseduretentionuofuwateruinutheubody.uEpinephrineucausesuin
creasesuinuhearturateuanduforceuofucontraction.uIncreaseducortisolusecretionuisudueutouACTH.uBr
eakdownuofufatuisudueutouglucagon.

PTS:u u 1 DIF: CognitiveuLevel:uRemembering

6. DuringuwhichuphaseuofutheucellucycleuisuDNAusynthesized?
a. G1
b. S
c. G2
d. M