GRADE A| (VERIFIED SOLUTIONS) (2025/ 2026 U PDATE)
1. What is distribution in pharmacology?: process by which the
drug becomes available to body fluids & tissues
2. What is protein binding %?: how much a drug is attracted to
protein
3. What happens once a drug is protein binded?: it can no longer
take effect 4. What are factors the affect distribution?: body
composition, liver disease (stays in body longer), kidney disease
(drug accumulates), protein binding %, malnourishment
5. What is a half-life?: The time it takes for one half of the
drug concentration to be eliminated from the body
6. What is a factor that could affect half time?: liver disease
(longer half time)
, 7. What are the 2 main labs for kidneys?: Blood Urea
Nitrogen (BUN) & creatinine - high values for both indicates kidney
malfunction
8. What is the pharmacodynamic phase?: what the drug does to
the body
9. What occurs in T0-T1?: onset of drug- the moment the drug hits
the bloodstream
10. What is MTC?: Maximum Therapeutic concentration -
above the mtc the drug can become toxic
11. What occurs if you get over the therapeutic window?:
Toxic Effects
12. What occurs if you go below the therapeutic window?:
Drug not effective
13. . What is receptor theory?: drugs act through receptors by
binding to the receptor site to produce or block a response
14.What are agonists?: what produces a response
, 15. What are antagonists?: drugs that block or prevent a
response
16. Where can you find adrenergic receptors?: throughout
the body
17. What are categories of drug action?: - stimulation or
depression (ex: ADHD)
- Replacement (ex:enzymes, hormones)
- Inhibition or killing of organisms
- Irritation (ex: laxatives)
18. What is a loading dose?: initial higher dose of a drug that
may be given at the beginning of treatment to RAPIDLY achieve a
therapeutic level
19. What are adverse reactions?: harmful, unintended side
effects (ex: rash, throat closing)
20. What are toxic effects?: adverse reactions due to too much
medication