BIO 351: MODULE 1 EXAM NOTES| QUESTIONS WITH CORRECT ANSWERS| LATEST UPDATE
GUARANTEED SUCCESS
Application of FGF8 coated beads induce limb mesenchymal cell proliferation. In contrast, FGF8
cpated beads implanted on the epidermis on the back do not promote proliferation. This
experiment is of? Competence
WHat would skin fibroblasts become if you induced expression of:
Oct4 (Pou5tf)
Myc
KIf4
Sox2 Induced pluripotent stem cells (iPSCs)
Signaling between the endosteal osteoblasts and hematopoietic stem cells (HSCs) in the bone
marrow niche are necessary for which of the following? Maintenance of HSC potency and
proliferation
Which of the following best describes the most important properties of the Yamanaka factors
for iPSC generation Pioneering transcription factors expressed in embryonic stem cells
Organoids are considered mini-tissues in a 3D culture dish. They rely on an extracellular matrix
artificially supplied to support organoid formation and growth. Organoids can recapitulate
many or all of the cell types found within a specific tissue. For example, intestinal organoids
contain the diverse array of absorptive and secretory cells found within the intestine that are
, required for intestine function. Given that organoids can regenerate differentiated cell types
within the tissue as well as self-renew to maintain the organoid upon multiple passges, what is
the likely cell-of-origin for an organoid to form? a stem cell
You want to study the process of development in a relatively unstudied species, the green
anole lizard. Which of the following is the best method for quantifying expression of as many
genes as possible in specific parts of the embryo? RNA-sequencing
In situ hybridization (ISH) detects the presence of which of the following___? mRNA
What molecule does Reverse Transcription-Polymerase Chain Reaction (RT-PCR) allow us to
examine? mRNA
Researchers did the experiment diagrammed below? Spots that light up red indicate what?
Genes expressed in cancer cells
RNA interference is a mechanism for silencing gene expression by acting on ____ mRNA
stability and translation
In the diagram below there is a description of gene X and a transgene. (Yellow boxed P indicates
the gene promoter.) Where would the transgene diagrammed be expressed? Only where
the gene X is expressed
GUARANTEED SUCCESS
Application of FGF8 coated beads induce limb mesenchymal cell proliferation. In contrast, FGF8
cpated beads implanted on the epidermis on the back do not promote proliferation. This
experiment is of? Competence
WHat would skin fibroblasts become if you induced expression of:
Oct4 (Pou5tf)
Myc
KIf4
Sox2 Induced pluripotent stem cells (iPSCs)
Signaling between the endosteal osteoblasts and hematopoietic stem cells (HSCs) in the bone
marrow niche are necessary for which of the following? Maintenance of HSC potency and
proliferation
Which of the following best describes the most important properties of the Yamanaka factors
for iPSC generation Pioneering transcription factors expressed in embryonic stem cells
Organoids are considered mini-tissues in a 3D culture dish. They rely on an extracellular matrix
artificially supplied to support organoid formation and growth. Organoids can recapitulate
many or all of the cell types found within a specific tissue. For example, intestinal organoids
contain the diverse array of absorptive and secretory cells found within the intestine that are
, required for intestine function. Given that organoids can regenerate differentiated cell types
within the tissue as well as self-renew to maintain the organoid upon multiple passges, what is
the likely cell-of-origin for an organoid to form? a stem cell
You want to study the process of development in a relatively unstudied species, the green
anole lizard. Which of the following is the best method for quantifying expression of as many
genes as possible in specific parts of the embryo? RNA-sequencing
In situ hybridization (ISH) detects the presence of which of the following___? mRNA
What molecule does Reverse Transcription-Polymerase Chain Reaction (RT-PCR) allow us to
examine? mRNA
Researchers did the experiment diagrammed below? Spots that light up red indicate what?
Genes expressed in cancer cells
RNA interference is a mechanism for silencing gene expression by acting on ____ mRNA
stability and translation
In the diagram below there is a description of gene X and a transgene. (Yellow boxed P indicates
the gene promoter.) Where would the transgene diagrammed be expressed? Only where
the gene X is expressed
