1. A client taking isoniazid (INH) for tuberculosis develops
numbness and tingling in their hands and feet. What should the
nurse anticipate?
A. The need for increased calcium
B. Administration of pyridoxine (vitamin B6)
C. Discontinuation of therapy
D. Addition of prednisone
Answer: B
Rationale: Isoniazid can cause peripheral neuropathy, often
prevented or treated with vitamin B6.
2. A client taking phenytoin shows swollen, bleeding gums. What
should the nurse recommend?
A. Discontinue the drug
B. Increase fluid intake
C. Practice good oral hygiene
D. Reduce dietary sugar
Answer: C
Rationale: Gingival hyperplasia is a known side effect. Encourage
oral care, not discontinuation.
3. A client is prescribed bupropion for smoking cessation. Which
side effect is most serious?
A. Dry mouth
B. Insomnia
C. Seizures
,D. Weight loss
Answer: C
Rationale: Bupropion lowers seizure threshold. Clients at risk (e.g.,
with eating disorders) need close monitoring.
4. A client with a penicillin allergy is prescribed cephalexin. What
is the nurse’s priority?
A. Administer as ordered
B. Ask about previous reaction type
C. Hold the dose for 30 minutes
D. Give with food
Answer: B
Rationale: Cross-sensitivity may occur. Ask if the client had a true
anaphylactic reaction before administering.
5. A nurse is educating a client on atorvastatin. What side effect
should the client report immediately?
A. Headache
B. Muscle pain
C. Drowsiness
D. Constipation
Answer: B
Rationale: Myopathy can occur with statins and may progress to
rhabdomyolysis. Report muscle pain immediately.
6. A nurse is preparing to administer metoprolol. Which
assessment is priority?
A. Respiratory rate
, B. Heart rate
C. Oxygen saturation
D. Blood glucose
Answer: B
Rationale: Metoprolol can cause bradycardia. Always check HR
before administering.
7. A nurse teaches a client taking cyclobenzaprine. Which
statement indicates understanding?
A. “I will take this long-term.”
B. “I can drink alcohol in moderation.”
C. “I should avoid driving until I know how it affects me.”
D. “It will help my heart condition.”
Answer: C
Rationale: Cyclobenzaprine causes drowsiness. Clients should
avoid driving or alcohol initially.
8. A nurse monitors a client taking lamotrigine. What adverse
effect should prompt discontinuation?
A. Rash
B. Constipation
C. Nausea
D. Drowsiness
Answer: A
Rationale: Lamotrigine can cause a life-threatening rash (e.g.,
Stevens-Johnson syndrome). Report immediately.
9. A client with COPD is on prednisone. Which instruction is
numbness and tingling in their hands and feet. What should the
nurse anticipate?
A. The need for increased calcium
B. Administration of pyridoxine (vitamin B6)
C. Discontinuation of therapy
D. Addition of prednisone
Answer: B
Rationale: Isoniazid can cause peripheral neuropathy, often
prevented or treated with vitamin B6.
2. A client taking phenytoin shows swollen, bleeding gums. What
should the nurse recommend?
A. Discontinue the drug
B. Increase fluid intake
C. Practice good oral hygiene
D. Reduce dietary sugar
Answer: C
Rationale: Gingival hyperplasia is a known side effect. Encourage
oral care, not discontinuation.
3. A client is prescribed bupropion for smoking cessation. Which
side effect is most serious?
A. Dry mouth
B. Insomnia
C. Seizures
,D. Weight loss
Answer: C
Rationale: Bupropion lowers seizure threshold. Clients at risk (e.g.,
with eating disorders) need close monitoring.
4. A client with a penicillin allergy is prescribed cephalexin. What
is the nurse’s priority?
A. Administer as ordered
B. Ask about previous reaction type
C. Hold the dose for 30 minutes
D. Give with food
Answer: B
Rationale: Cross-sensitivity may occur. Ask if the client had a true
anaphylactic reaction before administering.
5. A nurse is educating a client on atorvastatin. What side effect
should the client report immediately?
A. Headache
B. Muscle pain
C. Drowsiness
D. Constipation
Answer: B
Rationale: Myopathy can occur with statins and may progress to
rhabdomyolysis. Report muscle pain immediately.
6. A nurse is preparing to administer metoprolol. Which
assessment is priority?
A. Respiratory rate
, B. Heart rate
C. Oxygen saturation
D. Blood glucose
Answer: B
Rationale: Metoprolol can cause bradycardia. Always check HR
before administering.
7. A nurse teaches a client taking cyclobenzaprine. Which
statement indicates understanding?
A. “I will take this long-term.”
B. “I can drink alcohol in moderation.”
C. “I should avoid driving until I know how it affects me.”
D. “It will help my heart condition.”
Answer: C
Rationale: Cyclobenzaprine causes drowsiness. Clients should
avoid driving or alcohol initially.
8. A nurse monitors a client taking lamotrigine. What adverse
effect should prompt discontinuation?
A. Rash
B. Constipation
C. Nausea
D. Drowsiness
Answer: A
Rationale: Lamotrigine can cause a life-threatening rash (e.g.,
Stevens-Johnson syndrome). Report immediately.
9. A client with COPD is on prednisone. Which instruction is
