PEBC Questions with verified answers
"Date rape drug" Ans✓✓✓ Flunitrazepam (rohypnol)
1st generation antihistamine that is highly sedating Ans✓✓✓ Diphenhydramine
2nd generation antihistamines Ans✓✓✓ Fexofenadine
Loratadine
Cetirizine
5HT-1D/1B agonist used for migraine headaches Ans✓✓✓ Sumatriptan
Naratriptan
Rizatriptan
5HT-3 antagonist used in chemotherapeutic induced emesis (5) Ans✓✓✓
Aprepitant, Ondansetron, granisetron, dolasetron and palonosetron
A1a-selective blocker used for BPH Ans✓✓✓ Tamsulosin (Flomax)
Ace inhibitors are contraindicated in Ans✓✓✓ pregnancy and with hyperkalemia
ACE-I and ARB s/e's? Ans✓✓✓ Dry cough (not ARB), hyperkalemia, rarely
angioedema
Renal failure in renovascular dx (bilateral renal stenosis), volume depletion, or pts
on NSAIDs
,ACE-I DIs? Ans✓✓✓ increase K+ w/ potassium supplements and/or K+sparing
diuretics
lower hypotensive effect with NSAIDs and increase risk of renal dysfxn
Elevate Li levels (potential toxicity)
ACEI and ARBs should never be used together except? Ans✓✓✓ refractory HF
ACEI not first line therapy for which race? Ans✓✓✓ Black patients
Acetaminophen only has Ans✓✓✓ Antipyretic and analgesic activity
ACS or acute coronary syndrome include which conditions? Ans✓✓✓ Myocardial
infarction and unstable angina
ACTH analog used for diagnosis of patients with corticosteroid abnormality
Ans✓✓✓ Cosyntropin
Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter
release and pain transmission Ans✓✓✓ Presynaptic mu, delta, and kappa
receptors
additional s/e's with Labetalol due to alpha-blockade? Ans✓✓✓ dizziness,
edema, nasal congestion, postural hypotension
,ADH agonist used for pituitary diabetes insipidus Ans✓✓✓ Desmopressin
(DDAVP)
Agent for pernicious anemia Ans✓✓✓ Cyanocobalamin (Vit B12)
Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and
microsomal ethanol-oxidizing system (MEOS) Ans✓✓✓ Ethanol
Agent used for anemias associated with renal failure Ans✓✓✓ Erythropoietin
Agent used for closure of patent ductus arteriosus Ans✓✓✓ Indomethacin
Agent used for megaloblastic anemia (but does NOT reverse neurologic
symptoms) and decrease neural tube defects during pregnancy Ans✓✓✓ Folic
acid
Agent with greater affinity to 5HT2A receptor; reserved for refractory
schizophrenia, and can cause weight gain and agranulocytosis Ans✓✓✓
Clozapine
Agents for reduction of postpartum bleeding Ans✓✓✓ Oxytocin and ergonovine
Agents used in treatment of carcinoid tumor Ans✓✓✓ Cyproheptadine
Allopurinol treats chronic gout by inhibiting Ans✓✓✓ Xanthine oxidase
, Alpha 1 agonist toxicity Ans✓✓✓ Hypertension
Alpha 1selective blockers Ans✓✓✓ Prazosin
Terazosin
Doxazosin
(-AZOSIN ending)
Amino acid derivative for treatment of Type II diabetes Ans✓✓✓ Nateglinide
Anemia caused by trimethoprim Ans✓✓✓ Megaloblastic anemia
Angiotensin receptor blockers do NOT cause Ans✓✓✓ Dry cough
Anti-biotic frequently used for chronic UTI prophylaxis Ans✓✓✓
sulfamethoxazole/ trimethoprim
Anti-emetics used in association with anti-cancer drugs that are 5-HT3 (serotonin
receptor subtype ) antagonist Ans✓✓✓ Odansetron
Granisetron
Dolasetron
Palonosetron
Anti-estrogen used for estrogen receptor + breast cancer Ans✓✓✓ Tamoxifen
"Date rape drug" Ans✓✓✓ Flunitrazepam (rohypnol)
1st generation antihistamine that is highly sedating Ans✓✓✓ Diphenhydramine
2nd generation antihistamines Ans✓✓✓ Fexofenadine
Loratadine
Cetirizine
5HT-1D/1B agonist used for migraine headaches Ans✓✓✓ Sumatriptan
Naratriptan
Rizatriptan
5HT-3 antagonist used in chemotherapeutic induced emesis (5) Ans✓✓✓
Aprepitant, Ondansetron, granisetron, dolasetron and palonosetron
A1a-selective blocker used for BPH Ans✓✓✓ Tamsulosin (Flomax)
Ace inhibitors are contraindicated in Ans✓✓✓ pregnancy and with hyperkalemia
ACE-I and ARB s/e's? Ans✓✓✓ Dry cough (not ARB), hyperkalemia, rarely
angioedema
Renal failure in renovascular dx (bilateral renal stenosis), volume depletion, or pts
on NSAIDs
,ACE-I DIs? Ans✓✓✓ increase K+ w/ potassium supplements and/or K+sparing
diuretics
lower hypotensive effect with NSAIDs and increase risk of renal dysfxn
Elevate Li levels (potential toxicity)
ACEI and ARBs should never be used together except? Ans✓✓✓ refractory HF
ACEI not first line therapy for which race? Ans✓✓✓ Black patients
Acetaminophen only has Ans✓✓✓ Antipyretic and analgesic activity
ACS or acute coronary syndrome include which conditions? Ans✓✓✓ Myocardial
infarction and unstable angina
ACTH analog used for diagnosis of patients with corticosteroid abnormality
Ans✓✓✓ Cosyntropin
Activation of these receptors close Ca2+ ion channels to inhibit neurotransmitter
release and pain transmission Ans✓✓✓ Presynaptic mu, delta, and kappa
receptors
additional s/e's with Labetalol due to alpha-blockade? Ans✓✓✓ dizziness,
edema, nasal congestion, postural hypotension
,ADH agonist used for pituitary diabetes insipidus Ans✓✓✓ Desmopressin
(DDAVP)
Agent for pernicious anemia Ans✓✓✓ Cyanocobalamin (Vit B12)
Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and
microsomal ethanol-oxidizing system (MEOS) Ans✓✓✓ Ethanol
Agent used for anemias associated with renal failure Ans✓✓✓ Erythropoietin
Agent used for closure of patent ductus arteriosus Ans✓✓✓ Indomethacin
Agent used for megaloblastic anemia (but does NOT reverse neurologic
symptoms) and decrease neural tube defects during pregnancy Ans✓✓✓ Folic
acid
Agent with greater affinity to 5HT2A receptor; reserved for refractory
schizophrenia, and can cause weight gain and agranulocytosis Ans✓✓✓
Clozapine
Agents for reduction of postpartum bleeding Ans✓✓✓ Oxytocin and ergonovine
Agents used in treatment of carcinoid tumor Ans✓✓✓ Cyproheptadine
Allopurinol treats chronic gout by inhibiting Ans✓✓✓ Xanthine oxidase
, Alpha 1 agonist toxicity Ans✓✓✓ Hypertension
Alpha 1selective blockers Ans✓✓✓ Prazosin
Terazosin
Doxazosin
(-AZOSIN ending)
Amino acid derivative for treatment of Type II diabetes Ans✓✓✓ Nateglinide
Anemia caused by trimethoprim Ans✓✓✓ Megaloblastic anemia
Angiotensin receptor blockers do NOT cause Ans✓✓✓ Dry cough
Anti-biotic frequently used for chronic UTI prophylaxis Ans✓✓✓
sulfamethoxazole/ trimethoprim
Anti-emetics used in association with anti-cancer drugs that are 5-HT3 (serotonin
receptor subtype ) antagonist Ans✓✓✓ Odansetron
Granisetron
Dolasetron
Palonosetron
Anti-estrogen used for estrogen receptor + breast cancer Ans✓✓✓ Tamoxifen
