PHRD 515: MODULE 2 QUIZ PRACTICE
The pyruvate dehydrogenase complex catalyzes? - Answers :the oxidative
decarboxylation of pyruvate to acetyl-coA
The pyruvate dehydrogenase complex is regulated at different levels. Regulation by
reversible phosphorylation entails? - Answers :phosphorylation of E2 subunits by pdk
which will inhibit the complex
Which of the following TCA enzymes are regulated allosterically? - Answers :-citrate
synthase
-isocitrate dehydrogenase
-alpha-ketoglutarate dehydrogenase
Glycerol-P-dehydrogenase activity results in the formation of FPH4, at what site do
these
reducing equivalents enter the respiratory chain and how many ATP are generated? -
Answers :-q site; 2 atp
Most of the reducing equivalents in the TCA cycle are in the form of NADH, except one
enzyme that generates a reduced flavoprotein, FPH2. This enzyme is? - Answers
:succinate dehydrogenase complex II
Which one of the following enzymes activates fatty acids to undergo beta oxidation? -
Answers :acyl-coa synthetase
The catalytic machinery for the synthesis of fatty acids requires? - Answers :acetyl-coa
carboxylase and fatty acid synthase
Synthesis of triacylglycerols in adipose tissue requires? - Answers :-glycerol-p derived
from glucose
Which one of the following enzymes is required to obtain energy from ketone body
metabolism? - Answers :-succinyl-coa transferase
The largest pool of acetyl-CoA occurs in mitochondria and fatty acid synthesis in the
cytosol. How is acetyl-CoA transferred from mitochondria to cytosol? - Answers :-Citrate
Which of the following enzymes is a target for cholesterol reducing drugs? - Answers :-
hmg-coa reductase
Glucagon and epinephrine (fill in the blank about how it regulates fatty acid metabolism
under high carb diet) - Answers :-phosphorylate and activate hormone-sensitive lipase
Which one of the following is a ketogenic tissue? - Answers :liver
The pyruvate dehydrogenase complex catalyzes? - Answers :the oxidative
decarboxylation of pyruvate to acetyl-coA
The pyruvate dehydrogenase complex is regulated at different levels. Regulation by
reversible phosphorylation entails? - Answers :phosphorylation of E2 subunits by pdk
which will inhibit the complex
Which of the following TCA enzymes are regulated allosterically? - Answers :-citrate
synthase
-isocitrate dehydrogenase
-alpha-ketoglutarate dehydrogenase
Glycerol-P-dehydrogenase activity results in the formation of FPH4, at what site do
these
reducing equivalents enter the respiratory chain and how many ATP are generated? -
Answers :-q site; 2 atp
Most of the reducing equivalents in the TCA cycle are in the form of NADH, except one
enzyme that generates a reduced flavoprotein, FPH2. This enzyme is? - Answers
:succinate dehydrogenase complex II
Which one of the following enzymes activates fatty acids to undergo beta oxidation? -
Answers :acyl-coa synthetase
The catalytic machinery for the synthesis of fatty acids requires? - Answers :acetyl-coa
carboxylase and fatty acid synthase
Synthesis of triacylglycerols in adipose tissue requires? - Answers :-glycerol-p derived
from glucose
Which one of the following enzymes is required to obtain energy from ketone body
metabolism? - Answers :-succinyl-coa transferase
The largest pool of acetyl-CoA occurs in mitochondria and fatty acid synthesis in the
cytosol. How is acetyl-CoA transferred from mitochondria to cytosol? - Answers :-Citrate
Which of the following enzymes is a target for cholesterol reducing drugs? - Answers :-
hmg-coa reductase
Glucagon and epinephrine (fill in the blank about how it regulates fatty acid metabolism
under high carb diet) - Answers :-phosphorylate and activate hormone-sensitive lipase
Which one of the following is a ketogenic tissue? - Answers :liver
