BIO 2313 Genetics
HW 7
Question 1
Achondroplasia is a form of dwarfism that is inherited in humans as an autosomal dominant. A
survey in a small country showed that, within a 2-year period, there were 12 children with
normal parents born with this disorder out of a total of 420,000 births. What is the mutation rate
in mutations/locus/generation?
1.4 × 10–5
2.8 × 10–6
2.5 × 10–5
2.8 × 10–5
7.4 × 10–6
Question 2
Which of the following statements about somatic mutations is FALSE?
, Some may give rise to cancers in humans and other animals.
They may be inherited by daughter cells after cell division.
They may result in inactive gene products of the mutated genes.
They may result from both frameshift and base-pair substitution mutations.
They may be inherited in the offspring of mutated individuals.
Question 3
Insertion or removal of one or more nucleotide base pairs in DNA within a gene often
results in a _____ mutation.
transition
frameshift
reversion
HW 7
Question 1
Achondroplasia is a form of dwarfism that is inherited in humans as an autosomal dominant. A
survey in a small country showed that, within a 2-year period, there were 12 children with
normal parents born with this disorder out of a total of 420,000 births. What is the mutation rate
in mutations/locus/generation?
1.4 × 10–5
2.8 × 10–6
2.5 × 10–5
2.8 × 10–5
7.4 × 10–6
Question 2
Which of the following statements about somatic mutations is FALSE?
, Some may give rise to cancers in humans and other animals.
They may be inherited by daughter cells after cell division.
They may result in inactive gene products of the mutated genes.
They may result from both frameshift and base-pair substitution mutations.
They may be inherited in the offspring of mutated individuals.
Question 3
Insertion or removal of one or more nucleotide base pairs in DNA within a gene often
results in a _____ mutation.
transition
frameshift
reversion
