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individual matching individually match each control to a case
issues with case-control studies recall bias - have to ask cases and controls to accurately
remember potential exposures
analysis of case-control studies odds ratio - can't use relative risk because there is no
temporality
odds ratio of the probability of the event occurring to that of it not occuring
OR equal to 1 there is no evidence of an association between exposure and health
outcome
OR greater than 1 there is a positive association between exposure and health outcome
(may be causal)
, OR less than 1 there is a negative association between exposure and health outcome (the
exposure may be protective)
3 things that determine validity bias, confounding, random error
internal validity was the study done without bias, confounding, or random error
external validity is the study generalizable to all populations
selection bias study subjects don't represent the target population - most likely in case-
control or retrospective cohort
selection bias in case control occurs when researchers don't use same criteria for selection
controls as for selecting cases
self selection bias can occur if you have a case-control study that doesn't have high
participation rates if the decision to participate is related to the exposure and outcome