Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 1
Edition
MULTIPLE CHOICE w
1. Which name identifies a drug listed by the US Food
w w w w w w w w w
wand Drug Administration (FDA)?
w w w
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C w
The official name is the name under which a drug is listed
w w w w w w w w w w w
by the FDA. The brand name, or trademark, is the name
w w w w w w w w w w w
given to a drug by its manufacturer. The nonproprietary,
w w w w w w w w w
or generic, name is provided by the United States
w w w w w w w w w
Adopted Names Council.
w w w
Chapter 01: Drug Definitions, Standards, and Information Sources
w w w w w w w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 2
Edition
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
w w w w w w w w
DIF: Cognitive Level: Knowledge REF: p. 9 w w w w
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
w w w w w w w
wCare Environment TOP: Nursing Process Step: Assessment CON:
w w w w w w
wPatient Education w
2. Which source contains information specific to nutritional supplements?
w w w w w w w
a. USP Dictionary of USAN & International Drug Names
w w w w w w w
b. Natural Medicines Comprehensive Database w w w
c. United States Pharmacopoeia/National Formulary (USP NF)
w w w w w
d. Drug Interaction Facts w w
ANS: C w
United States Pharmacopoeia/National Formulary contains information specific to
w w w w w w w
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
w w w w w w w w w w w w
wcompilation of drug names, pronunciation guide, and possible future FDA approved drugs;
w w w w w w w w w w w
wit does not include nutritional supplements. Natural Medicines Comprehensive Database
w w w w w w w w w
wcontains
evidence-based information on herbal medicines and herbal combination products; it does
w w w w w w w w w w
not include information specific to nutritional supplements. Drug Interaction Facts
w w w w w w w w w w
wcontains comprehensive information on drug interaction facts; it does not include
w w w w w w w w w w
wnutritional supplements. w
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
w w w w w
NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
w w w w w w w w
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
w w w w w w w w w w w w w
a. Drug Facts and Comparisons w w w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 3
Edition
b. Drug Interaction Facts w w
c. Handbook on Injectable Drugs w w w
d. Martindale—The Complete Drug Reference w w w
ANS: A w
Drug Facts and Comparisons contains drug monographs that describe all drugs in
w w w w w w w w w w w
a therapeutic class. Monographs are formatted as tables to allow comparison of
w w w w w w w w w w w w
similar products, brand names, manufacturers, cost indices, and available dosage
w w w w w w w w w w
forms Online version is available.
w w w w w
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 w w w w w w
OBJ: 3 w NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
w w w w w w w w w w w
4. Which drug reference contains monographs about virtually every single-entity drug
w w w w w w w w w
available in the United States and describes therapeutic uses of drugs, including approved
w w w w w w w w w w w w w
wand unapproved uses?
w w
a. Martindale: The Complete Drug Reference w w w w
b. AHFS Drug Information w w
c. Drug Reference w
d. Drug Facts and Comparisons
w w w
ANS: B w
AHFS Drug Information contains monographs about virtually every single-entity drug
w w w w w w w w w
available in the United States and describes therapeutic uses of drugs, including approved
w w w w w w w w w w w w w
and unapproved uses.
w w w
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 w w w w w w
OBJ: 3 w NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Planning
w CON: Safety | Patient Education | Clinical Judgment
w w w w w w w w w w
5. Which online drug reference makes available to healthcare providers and the public a
w w w w w w w w w w w w
wstandard, comprehensive, up-to-date look up and downloadable resource about
w w w w w w w w
medicines?
w
a. American Drug Index w w
b. American Hospital Formulary w w
c. DailyMed
d. Drug Reference w
ANS: C w
DailyMed makes available to healthcare providers and the public a standard,
w w w w w w w w w w
comprehensive, up-to-date look up and downloadable resource about medicines. The
w w w w w w w w w w
American Drug Index is not appropriate for patient use. The American Hospital
w w w w w w w w w w w w
Formulary is not appropriate for patient use. The drug reference is not appropriate for
w w w w w w w w w w w w w w
patient use.
w w
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4
w OBJ: 3 w w w w w w w
NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Implementation
w w w w
CON: Safety | Patient Education | Clinical Judgment
w w w w w w w
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
w w w w w w w w w w w w w w
a. Federal Food, Drug, and Cosmetic Act (1938)
w w w w w w
b. Durham Humphrey Amendment (1952) w w w
w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 4
Edition
c. Controlled Substances Act (1970) w w w
d. Kefauver Harris Drug Amendment (1962) w w w w
ANS: A w
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
w w w w w w w w w w w w w w
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
w w w w w w w w w w w w w
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds of
w w w w w w w w w w w w w
drugs that cannot be used safely without medical supervision and restricts their sale to
w w w w w w w w w w w w w w
prescription by a licensed practitioner. The Controlled Substances Act addresses only
w w w w w w w w w w w
controlled substances and their categorization. The Kefauver Harris Drug Amendment
w w w w w w w w w w
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to
w w w w w w w w w w w w w w
the FDA the effectiveness of their products before marketing them.
w w w w w w w w w w
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 w w w w w w
OBJ: 5 w NAT: NCLEX Client Needs Category: Physiological w w w w w
Integrity TOP: Nursing Process Step: Assessment
w w w w w w
CON: Safety | Patient Education | Evidence | Health Care Law
w w w w w w w w w w
7. Which classification does meperidine (Demerol) fall under?
w w w w w w
a. I
b. II
c. III
d. IV
ANS: B w
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead
w w w w w w w w w w w w w w w w
to severe psychological and physical dependence. Schedule I drugs have high potential for
w w w w w w w w w w w w w
abuse and no recognized medical use. Schedule III drugs have some potential for abuse.
w w w w w w w w w w w w w w
Use may lead to low to moderate physical dependence or high psychological dependence.
w w w w w w w w w w w w w
Schedule IV drugs have low potential for abuse. Use may lead to limited physical or
w w w w w w w w w w w w w w w
psychological dependence.
w w
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 w w w w w
NAT: NCLEX Client Needs Category: Safe, Effective Care
w w w w w w w w
Environment
w
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
w w w w w w w w w w
8. Which action would the FDA take to expedite drug development and approval for an
w w w w w w w w w w w w w
woutbreak of smallpox? w w
a. List smallpox as a health orphan disease.
w w w w w w
b. Omit the preclinical research phase.
w w w w
c. Extend the clinical research phase. w w w w
d. Fast track the investigational drug.
w w w w
ANS: D w
Once the Investigational New Drug Application has been approved, the drug can receive
w w w w w w w w w w w w
highest priority within the agency, which is called fast tracking. A smallpox outbreak
w w w w w w w w w w w w w
would become a priority concern in the world. Orphan diseases are not researched in a
w w w w w w w w w w w w w w w
priority manner. Preclinical research is not omitted. Extending any phase of the research
w w w w w w w w w w w w w
would mean a longer time to develop a vaccine. The FDA must ensure that all phases of the
w w w w w w w w w w w w w w w w w w
preclinical and clinical research phase have been completed in a safe manner.
w w w w w w w w w w w w
DIF: Cognitive Level: Knowledge w w REF: w w p. 7 w OBJ: 5 w
w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
w w w w w w w w 1
Edition
MULTIPLE CHOICE w
1. Which name identifies a drug listed by the US Food
w w w w w w w w w
wand Drug Administration (FDA)?
w w w
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C w
The official name is the name under which a drug is listed
w w w w w w w w w w w
by the FDA. The brand name, or trademark, is the name
w w w w w w w w w w w
given to a drug by its manufacturer. The nonproprietary,
w w w w w w w w w
or generic, name is provided by the United States
w w w w w w w w w
Adopted Names Council.
w w w
Chapter 01: Drug Definitions, Standards, and Information Sources
w w w w w w w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 2
Edition
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
w w w w w w w w
DIF: Cognitive Level: Knowledge REF: p. 9 w w w w
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
w w w w w w w
wCare Environment TOP: Nursing Process Step: Assessment CON:
w w w w w w
wPatient Education w
2. Which source contains information specific to nutritional supplements?
w w w w w w w
a. USP Dictionary of USAN & International Drug Names
w w w w w w w
b. Natural Medicines Comprehensive Database w w w
c. United States Pharmacopoeia/National Formulary (USP NF)
w w w w w
d. Drug Interaction Facts w w
ANS: C w
United States Pharmacopoeia/National Formulary contains information specific to
w w w w w w w
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
w w w w w w w w w w w w
wcompilation of drug names, pronunciation guide, and possible future FDA approved drugs;
w w w w w w w w w w w
wit does not include nutritional supplements. Natural Medicines Comprehensive Database
w w w w w w w w w
wcontains
evidence-based information on herbal medicines and herbal combination products; it does
w w w w w w w w w w
not include information specific to nutritional supplements. Drug Interaction Facts
w w w w w w w w w w
wcontains comprehensive information on drug interaction facts; it does not include
w w w w w w w w w w
wnutritional supplements. w
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
w w w w w
NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
w w w w w w w w
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
w w w w w w w w w w w w w
a. Drug Facts and Comparisons w w w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 3
Edition
b. Drug Interaction Facts w w
c. Handbook on Injectable Drugs w w w
d. Martindale—The Complete Drug Reference w w w
ANS: A w
Drug Facts and Comparisons contains drug monographs that describe all drugs in
w w w w w w w w w w w
a therapeutic class. Monographs are formatted as tables to allow comparison of
w w w w w w w w w w w w
similar products, brand names, manufacturers, cost indices, and available dosage
w w w w w w w w w w
forms Online version is available.
w w w w w
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 w w w w w w
OBJ: 3 w NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
w w w w w w w w w w w
4. Which drug reference contains monographs about virtually every single-entity drug
w w w w w w w w w
available in the United States and describes therapeutic uses of drugs, including approved
w w w w w w w w w w w w w
wand unapproved uses?
w w
a. Martindale: The Complete Drug Reference w w w w
b. AHFS Drug Information w w
c. Drug Reference w
d. Drug Facts and Comparisons
w w w
ANS: B w
AHFS Drug Information contains monographs about virtually every single-entity drug
w w w w w w w w w
available in the United States and describes therapeutic uses of drugs, including approved
w w w w w w w w w w w w w
and unapproved uses.
w w w
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 w w w w w w
OBJ: 3 w NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Planning
w CON: Safety | Patient Education | Clinical Judgment
w w w w w w w w w w
5. Which online drug reference makes available to healthcare providers and the public a
w w w w w w w w w w w w
wstandard, comprehensive, up-to-date look up and downloadable resource about
w w w w w w w w
medicines?
w
a. American Drug Index w w
b. American Hospital Formulary w w
c. DailyMed
d. Drug Reference w
ANS: C w
DailyMed makes available to healthcare providers and the public a standard,
w w w w w w w w w w
comprehensive, up-to-date look up and downloadable resource about medicines. The
w w w w w w w w w w
American Drug Index is not appropriate for patient use. The American Hospital
w w w w w w w w w w w w
Formulary is not appropriate for patient use. The drug reference is not appropriate for
w w w w w w w w w w w w w w
patient use.
w w
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4
w OBJ: 3 w w w w w w w
NAT: NCLEX Client Needs Category: Physiological Integrity
w w w w w w w
TOP: Nursing Process Step: Implementation
w w w w
CON: Safety | Patient Education | Clinical Judgment
w w w w w w w
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
w w w w w w w w w w w w w w
a. Federal Food, Drug, and Cosmetic Act (1938)
w w w w w w
b. Durham Humphrey Amendment (1952) w w w
w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
w w w w w w w w 4
Edition
c. Controlled Substances Act (1970) w w w
d. Kefauver Harris Drug Amendment (1962) w w w w
ANS: A w
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
w w w w w w w w w w w w w w
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
w w w w w w w w w w w w w
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds of
w w w w w w w w w w w w w
drugs that cannot be used safely without medical supervision and restricts their sale to
w w w w w w w w w w w w w w
prescription by a licensed practitioner. The Controlled Substances Act addresses only
w w w w w w w w w w w
controlled substances and their categorization. The Kefauver Harris Drug Amendment
w w w w w w w w w w
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to
w w w w w w w w w w w w w w
the FDA the effectiveness of their products before marketing them.
w w w w w w w w w w
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 w w w w w w
OBJ: 5 w NAT: NCLEX Client Needs Category: Physiological w w w w w
Integrity TOP: Nursing Process Step: Assessment
w w w w w w
CON: Safety | Patient Education | Evidence | Health Care Law
w w w w w w w w w w
7. Which classification does meperidine (Demerol) fall under?
w w w w w w
a. I
b. II
c. III
d. IV
ANS: B w
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead
w w w w w w w w w w w w w w w w
to severe psychological and physical dependence. Schedule I drugs have high potential for
w w w w w w w w w w w w w
abuse and no recognized medical use. Schedule III drugs have some potential for abuse.
w w w w w w w w w w w w w w
Use may lead to low to moderate physical dependence or high psychological dependence.
w w w w w w w w w w w w w
Schedule IV drugs have low potential for abuse. Use may lead to limited physical or
w w w w w w w w w w w w w w w
psychological dependence.
w w
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 w w w w w
NAT: NCLEX Client Needs Category: Safe, Effective Care
w w w w w w w w
Environment
w
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
w w w w w w w w w w
8. Which action would the FDA take to expedite drug development and approval for an
w w w w w w w w w w w w w
woutbreak of smallpox? w w
a. List smallpox as a health orphan disease.
w w w w w w
b. Omit the preclinical research phase.
w w w w
c. Extend the clinical research phase. w w w w
d. Fast track the investigational drug.
w w w w
ANS: D w
Once the Investigational New Drug Application has been approved, the drug can receive
w w w w w w w w w w w w
highest priority within the agency, which is called fast tracking. A smallpox outbreak
w w w w w w w w w w w w w
would become a priority concern in the world. Orphan diseases are not researched in a
w w w w w w w w w w w w w w w
priority manner. Preclinical research is not omitted. Extending any phase of the research
w w w w w w w w w w w w w
would mean a longer time to develop a vaccine. The FDA must ensure that all phases of the
w w w w w w w w w w w w w w w w w w
preclinical and clinical research phase have been completed in a safe manner.
w w w w w w w w w w w w
DIF: Cognitive Level: Knowledge w w REF: w w p. 7 w OBJ: 5 w
w
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
w w w w w w w w w
