Phar 100 Questions and Correct
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Graded
Ancient Greece, Theophrastus
Ans: -textbook on therapeutics
-opium (codeine and morphine)
-codeine: mild pain relief
-morphine: intense pain relief
Ancient Egypt, Papyrus
Ans: -purgatives
-senna still available and used today
Ancient China
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Ans: -earliest drug experiments 2700 BC
-classified according to taste
-Mua Huang: medium drug for cough, flu, fevers
-Ephedrine from mua huang (for asthma or derivative decongestant)
Curare
Ans: -dipped arrows
-cause paralysis and death in animals
-later used by anesthetists
Ergot (what is it, what are the three things it causes?)
Ans: -fungus grows on rye, contaminated bread, killed people in Russia
-caused mental frenzy, hallucinations, convulsions
-constrict blood supply (burning sensation, limbs fall off)
-violent uterine contractions (sometimes used to speed up labour)
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What can be made from ergot? (3)
Ans: -LSD
-Ergotamine: migraine treatment if from pulsation of blood vessels(bc
constrict blood supply)
-Ergonovine: arrest uterine bleeding after childbirth
Reserpine and Chlorpromazine (what is it used for and where does it
come from)
Ans: -rauwolfia plant
-reduce tension, anxiety, lower blood pressure
-calm mentally ill patients (calmed aggressive animals)
-correct dose hard to determine
LSD (what does it stand for, where does it come from and what are
its effects?)
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Ans: -Lysergic Acid Diethylamide
-ergot
-psychedelic effects
Historical anaesthetics
Ans: -nitrous oxide
-ether
Paul Ehrlich (3)
Ans: -organoarsenicals (arsenic and organic molecules)
-selectively bind parasites
-lead to syphilis cure
Gerhard Domagk (3)