And Answers 2025
90% of patients with primary biliary cirrhosis have antibodies to M2. What is the most detailed
description of where M2 is located? - Answer - *inner mitochondrial membrane*
Why do you *not* refrigerate a CSF collected for bacterial culture? - Answer - *Neisseria &
Haemophilus are very sensitive to cold*
What is the estimated risk of a 45-year-old mother carrying a baby with any chromosomal
abnormality? - Answer - *1 in 20*
The TDx FLM test is an automated test that indicates - Answer - *amount of surfactant in
amniotic fluid, & therefore fetal lung maturity*
In normal pregnancy, hemoglobin falls because - Answer - *plasma volume expands more than
erythrocyte mass*
Centrally obese patient has overnight dexamethasone suppression test with morning cortisol
level of 15 ug/dL (expected normal result < 5 ug/dL). ACTH level is below reference range.
Patient most likely has - Answer - adrenal adenoma
What is the correct terminology used in reporting pre-malignant cervical cytology lesion in the
Bethesda System? - Answer - *Low grade squamous intraepithelial lesion (LGSIL)*
What is the best way to submit a lymph node in order to work up a suspicion of malignant
lymphoma? - Answer - *Delivered to lab fresh, sterile, & moistened with saline*
Most common site of origin of chondrosarcoma - Answer - *pelvic & shoulder girdles*
,Soft, gray, gelatinous tumor removed from sacrococcygeal area of a 46-year-old man contains
physaliphorous cells histologically. Best diagnosis is: - Answer - *chordoma*
2-year-old child with HT, diarrhea, large abdominal mass, & elevated homovainillic acid most
likely has a - Answer - *neuroblastoma*
What occurs in a type & cross match but not type & screen? - Answer - *Compatible blood is
reserved for the patient*
Transfusion of fresh frozen plasma is typically type specific because the plasma... - Answer - may
contain anti-A & anti-B Abs
A 55-year-old gentleman with acute GI bleeding required transfusion of packed RBCs. Patient
blood type B-positive, began receiving first unit of a B-positive packed red blood cells. Twenty
minutes after transfusion began, patient complained of chills & shaking. The nurse noted no
rashes, but vital signs revealed the following:
Before transfusion:
Temp = 99.2
BP = 125/85 mmHg
Pulse = 75
Respiration = 14
During transfusion:
Temp = 102.4
BP = 140/105
Pulse = 96
, Respiration = 18
Transfusion was stopped, & the resident determined that a transfusion reaction had occurred.
The bag of blood, as well as blood & urine samples from the patient along with the paperwork
were sent to the blood bank. The blood bank workup revealed no clerical error, & all repeat
testing was consistent with pre-transfusion results. The urine was clear. The nurse administered
Tylenol & Demerol, & the patient responded.
The etiology of this tran - Answer - *Febrile non-hemolytic*
Description of TRALI - Answer - - donor should not donate plasma-containing products in the
future
- non-cardiogenic pulmonary edema occurs
- occurs within minutes to several hours of transfusion
- involves passive transfer of fonor anti-granulocytic Abs into the recipient
Patient develops itching & an erythematous rash while receiving fresh frozen plasma (FFP), with
no significant change in the vital signs. This pnenomenon is due to - Answer - *Plasma proteins
within transfused unit of FFP*
heberden's node associated with - Answer - osteoarthritis
HLA DR4 associated with - Answer - *Rheumatoid arthritis*
Burkitt lymphoma gene - Answer - *c-Myc*
What organ listed best withstands flames & heat best? - Answer - *uterus*