ANCC IQ domain 1
Study online at https://quizlet.com/_a1pqp7
1. 2 yr. old child with Fetal Alcohol Syn- small head, short eye lid opening, flat midface,
drome (FAS) smooth philtrum, underdeveloped jaw, thin up-
per lip, and short nose
2. Neuroleptic Malignant Syndrome (NMS) - Acute mental status change, muscular rigidity,
and autonomic instability (fever)
3. Elderly pt c/o tinnitus; the PMHNP would - Unilateral tinnitus (ringing in the ears) may be
associate which of the following findings the first symptom of an acoustic neuroma
with an acoustic neuroma? - Sx/sx infection of the ear - perforation of tym-
panic membrane, inflammation of the middle
ear, and suppuration of the labyrinth
4. Brain structure is activated in patients - Amygdala is important in mediation of fear,
with severe anxiety (fear, panic, extreme anxiety, and panic
anxiety)
5. Which of the following does not reflect -FALSE: decreasing GABA in the mesolimbic cor-
current understanding of neurotrans- tex diminishes symptoms of anxiety
mitter pathways implicated in anxiety Rationale: GABA (Gamma-aminobutyric acid) is
disorders? the most abundant inhibitory neurotransmit-
-FALSE: decreasing GABA in the ter in the brain. Decreasing GABA would in-
mesolimbic cortex diminishes symp- crease anxiety. Benzodiazepines are used to
toms of anxiety bind with GABA receptors to potentiate the anx-
-TRUE: increasing serotonergic activity in iolytic (calming) effects of GABA. The other re-
the amygdala diminishes symptoms of sponses are all accurate regarding effect on
anxiety anxiety symptoms.
-TRUE: decreasing norepinephrine in the
locus ceruleus diminishes symptoms of
anxiety
-TRUE: increased levels of CRF in
, ANCC IQ domain 1
Study online at https://quizlet.com/_a1pqp7
the amygdala, hippocampus and locus
ceruleus increases symptoms of anxiety
6. While treating a 12-year-old boy for -long head and ears, short stature, hyperexten-
ADHD, the PMHNP observes which of sible joints
the following physical features that raise Rationale: Etiological factors in mental retar-
concerns for genetic evaluation for Frag- dation can be primarily genetic, developmen-
ile X Syndrome? tal, acquired, or in combination. Genetic caus-
-obesity, small stature, small hands and es included chromosomal and inherited con-
feet, hypotonia ditions. Many of these genetic disorders have
-café au lait spots on face and arms, neu- characteristic physical features that warrant ge-
rofibromas netic testing for confirmatory diagnosis. Fragile
-long head and ears, short stature, hy- X Syndrome occurs in about 1 of every 1,000
perextensible joints males and 1 of every 2,000 females. The typi-
-small stature, short palpebral fissure, cal phenotype includes a large, long head and
inner epicanthal folds ears, short stature, hyperextensible joints, and
postpubertal macroorchidism. The mentalretar-
dation ranges from mild to severe. There is
high rate of comorbid ADHD, learning disorder,
and pervasive developmental disorders, such as
autism. Café au lait spots and neurofibromas
are common in von Recklinghausen's disease.
Obesity, small stature, small hands and feet,
hypotonia, and hypogonadism are characteris-
tic of Prader-Willi Syndrome. Small head, short
palpebral fissure, and inner epicanthal folds are
characteristic of fetal alcohol syndrome.
7. Which of the following patients with gen- -40-year-old Asian male
eralized anxiety disorder is most like- Rationale: The frequency of poor metabolizers
ly to be a CYP 2C19 poor metabolizer of CYP 2C19 is low among Caucasians (3%),
and have an exaggerated response to intermediate among African Americans (18%),
, ANCC IQ domain 1
Study online at https://quizlet.com/_a1pqp7
diazepam (Valium) 5 mg TID with in- and higher in Asian and Japanese populations
creased sedation, central nervous sys- (up to 20%).
tem, and cognitive side effects?
-40-year-old Asian male
-30-year-old African American male
20-year-old African American male
50-year-old Caucasian male
8. Which serotonin receptor antagonism -5HT2A
makes an antipsychotic "atypical"? Rationale: The mechanism of action that makes
-5HT2A an antipsychotic medication "atypical" is related
-5HT1A to the 5HT2A receptor antagonism and D2 re-
-5HT4A ceptor antagonism.
-5HT3A -5HT1A
-5HT4A
-5HT3A
9. Which mood stabilizer is most associ- -lamotrigine (Lamictal)
ated with a potentially life-threatening Lamotrigine is associated with a rare, serious,
rash? and potentially life-threatening rash (Steven
Johnsons syndrome
10. Which of the following findings would height 43 inches, weight 55 lbs
raise concern in a pre-school wellness Rationale: Body Mass Index (BMI) calculated for
exam for a 5-year-old girl? this height and weight is 21, which is greater
than 95th percentile for her age, placing her in
overweight category. Calculation: Weight (lbs)
/Stature (inches) / Stature (inches) x 703 = BMI
BMI = 703 x weight (lbs) = 703 x 55
[Height (in)]2 432
Or Weight (kg)/ Stature (cm)/ Stature (cm) x
10,000 = BMI.
Study online at https://quizlet.com/_a1pqp7
1. 2 yr. old child with Fetal Alcohol Syn- small head, short eye lid opening, flat midface,
drome (FAS) smooth philtrum, underdeveloped jaw, thin up-
per lip, and short nose
2. Neuroleptic Malignant Syndrome (NMS) - Acute mental status change, muscular rigidity,
and autonomic instability (fever)
3. Elderly pt c/o tinnitus; the PMHNP would - Unilateral tinnitus (ringing in the ears) may be
associate which of the following findings the first symptom of an acoustic neuroma
with an acoustic neuroma? - Sx/sx infection of the ear - perforation of tym-
panic membrane, inflammation of the middle
ear, and suppuration of the labyrinth
4. Brain structure is activated in patients - Amygdala is important in mediation of fear,
with severe anxiety (fear, panic, extreme anxiety, and panic
anxiety)
5. Which of the following does not reflect -FALSE: decreasing GABA in the mesolimbic cor-
current understanding of neurotrans- tex diminishes symptoms of anxiety
mitter pathways implicated in anxiety Rationale: GABA (Gamma-aminobutyric acid) is
disorders? the most abundant inhibitory neurotransmit-
-FALSE: decreasing GABA in the ter in the brain. Decreasing GABA would in-
mesolimbic cortex diminishes symp- crease anxiety. Benzodiazepines are used to
toms of anxiety bind with GABA receptors to potentiate the anx-
-TRUE: increasing serotonergic activity in iolytic (calming) effects of GABA. The other re-
the amygdala diminishes symptoms of sponses are all accurate regarding effect on
anxiety anxiety symptoms.
-TRUE: decreasing norepinephrine in the
locus ceruleus diminishes symptoms of
anxiety
-TRUE: increased levels of CRF in
, ANCC IQ domain 1
Study online at https://quizlet.com/_a1pqp7
the amygdala, hippocampus and locus
ceruleus increases symptoms of anxiety
6. While treating a 12-year-old boy for -long head and ears, short stature, hyperexten-
ADHD, the PMHNP observes which of sible joints
the following physical features that raise Rationale: Etiological factors in mental retar-
concerns for genetic evaluation for Frag- dation can be primarily genetic, developmen-
ile X Syndrome? tal, acquired, or in combination. Genetic caus-
-obesity, small stature, small hands and es included chromosomal and inherited con-
feet, hypotonia ditions. Many of these genetic disorders have
-café au lait spots on face and arms, neu- characteristic physical features that warrant ge-
rofibromas netic testing for confirmatory diagnosis. Fragile
-long head and ears, short stature, hy- X Syndrome occurs in about 1 of every 1,000
perextensible joints males and 1 of every 2,000 females. The typi-
-small stature, short palpebral fissure, cal phenotype includes a large, long head and
inner epicanthal folds ears, short stature, hyperextensible joints, and
postpubertal macroorchidism. The mentalretar-
dation ranges from mild to severe. There is
high rate of comorbid ADHD, learning disorder,
and pervasive developmental disorders, such as
autism. Café au lait spots and neurofibromas
are common in von Recklinghausen's disease.
Obesity, small stature, small hands and feet,
hypotonia, and hypogonadism are characteris-
tic of Prader-Willi Syndrome. Small head, short
palpebral fissure, and inner epicanthal folds are
characteristic of fetal alcohol syndrome.
7. Which of the following patients with gen- -40-year-old Asian male
eralized anxiety disorder is most like- Rationale: The frequency of poor metabolizers
ly to be a CYP 2C19 poor metabolizer of CYP 2C19 is low among Caucasians (3%),
and have an exaggerated response to intermediate among African Americans (18%),
, ANCC IQ domain 1
Study online at https://quizlet.com/_a1pqp7
diazepam (Valium) 5 mg TID with in- and higher in Asian and Japanese populations
creased sedation, central nervous sys- (up to 20%).
tem, and cognitive side effects?
-40-year-old Asian male
-30-year-old African American male
20-year-old African American male
50-year-old Caucasian male
8. Which serotonin receptor antagonism -5HT2A
makes an antipsychotic "atypical"? Rationale: The mechanism of action that makes
-5HT2A an antipsychotic medication "atypical" is related
-5HT1A to the 5HT2A receptor antagonism and D2 re-
-5HT4A ceptor antagonism.
-5HT3A -5HT1A
-5HT4A
-5HT3A
9. Which mood stabilizer is most associ- -lamotrigine (Lamictal)
ated with a potentially life-threatening Lamotrigine is associated with a rare, serious,
rash? and potentially life-threatening rash (Steven
Johnsons syndrome
10. Which of the following findings would height 43 inches, weight 55 lbs
raise concern in a pre-school wellness Rationale: Body Mass Index (BMI) calculated for
exam for a 5-year-old girl? this height and weight is 21, which is greater
than 95th percentile for her age, placing her in
overweight category. Calculation: Weight (lbs)
/Stature (inches) / Stature (inches) x 703 = BMI
BMI = 703 x weight (lbs) = 703 x 55
[Height (in)]2 432
Or Weight (kg)/ Stature (cm)/ Stature (cm) x
10,000 = BMI.
