PN 2005 Drugs questions and answers
Albuterol Sulfate ✔✔Relaxes bronchial, uterine, and vascular smooth muscle by
stimulating beta2 receptors.
Alprazolam ✔✔Unknown. Probably potentiates the effects of GABA, depresses
the spread of seizure activity.
Amitriptyline ✔✔Unknown. A TCA that increases the amount of norepinephrine,
serotonin, or both in the CNS by blocking their reuptake by the presynaptic
neutrons
Amoxicilin ✔✔Inhibits cell-wall synthesis during bacterial multiplication.
Aspirin ✔✔Through to produce analgesia and exert its anti-inflammatory effect by
inhibiting prostaglandin and other substances that sensitize pain receptors. Drug
may relieve fever though central action in the hypothalamic heat-regulating
centre. In low doses, drug appears to interfere with clothing by keeping a platelet-
aggregating substance from forming.
Atorvastatin Calcium ✔✔Inhibits HMG-CoA reductase, an early (and rate-limiting)
step in cholesterol biosynthesis.
Bacitracin ✔✔Prevents phosphorylation of bactoprenol.
, Baclofen ✔✔Hyperpolarizes fibres to reduce impulse transmission. Appears to
reduce transmissions of impulse from the spinal cord to skeletal muscle, thus
decreasing the frequency and amplitude the muscle spasms in patient with spinal
cord lesions.
Bisacodyl Fumarate ✔✔Selectively blocks cardiac adrenoceptors, reducing resting
and exercise HR, decreasing cardiac output, depressing renin secretion, and
decreasing tonic sympathetic outflow from the vasomotor centres in the brain.
Captopril ✔✔Inhibits ACE, preventing conversions of angiotensin 1 to angiotensin
2, a potent vasocontrictor. Less angiotensin 2 decreases peripheral arterial
resistance, decreasing aldosterone secretion, which reduces sodium and water
retention and lowers BP.
Carbidopa-levodopa (Sinemet) ✔✔Converted to dopamine via the action of
naturally occurring enzyme called DOPA decarboxylase. Improves symptoms of
parkinson's disease.
Ciprofloxacin ✔✔Inhibits bacterial DNA synthesis, mainly by blocking DNA gyrase;
bactericidal.
Citalopram Hydrobromide ✔✔Probably linked to potentiation of serotonergic
activity in the CNS resulting from inhibiting of neuronal reuptake of serotonin.
Albuterol Sulfate ✔✔Relaxes bronchial, uterine, and vascular smooth muscle by
stimulating beta2 receptors.
Alprazolam ✔✔Unknown. Probably potentiates the effects of GABA, depresses
the spread of seizure activity.
Amitriptyline ✔✔Unknown. A TCA that increases the amount of norepinephrine,
serotonin, or both in the CNS by blocking their reuptake by the presynaptic
neutrons
Amoxicilin ✔✔Inhibits cell-wall synthesis during bacterial multiplication.
Aspirin ✔✔Through to produce analgesia and exert its anti-inflammatory effect by
inhibiting prostaglandin and other substances that sensitize pain receptors. Drug
may relieve fever though central action in the hypothalamic heat-regulating
centre. In low doses, drug appears to interfere with clothing by keeping a platelet-
aggregating substance from forming.
Atorvastatin Calcium ✔✔Inhibits HMG-CoA reductase, an early (and rate-limiting)
step in cholesterol biosynthesis.
Bacitracin ✔✔Prevents phosphorylation of bactoprenol.
, Baclofen ✔✔Hyperpolarizes fibres to reduce impulse transmission. Appears to
reduce transmissions of impulse from the spinal cord to skeletal muscle, thus
decreasing the frequency and amplitude the muscle spasms in patient with spinal
cord lesions.
Bisacodyl Fumarate ✔✔Selectively blocks cardiac adrenoceptors, reducing resting
and exercise HR, decreasing cardiac output, depressing renin secretion, and
decreasing tonic sympathetic outflow from the vasomotor centres in the brain.
Captopril ✔✔Inhibits ACE, preventing conversions of angiotensin 1 to angiotensin
2, a potent vasocontrictor. Less angiotensin 2 decreases peripheral arterial
resistance, decreasing aldosterone secretion, which reduces sodium and water
retention and lowers BP.
Carbidopa-levodopa (Sinemet) ✔✔Converted to dopamine via the action of
naturally occurring enzyme called DOPA decarboxylase. Improves symptoms of
parkinson's disease.
Ciprofloxacin ✔✔Inhibits bacterial DNA synthesis, mainly by blocking DNA gyrase;
bactericidal.
Citalopram Hydrobromide ✔✔Probably linked to potentiation of serotonergic
activity in the CNS resulting from inhibiting of neuronal reuptake of serotonin.
