NU 301 Pharmacology – FINAL Exam Questions
With Correct Answers 100% Verified.
Pharmacodynamics - Answer✔The process by which a medication works on the body.
Pharmacokinetics - Answer✔The process by which drugs are absorbed, distributed within the
body, metabolized, and excreted.
Half-life - Answer✔Time it takes for a drug to decrease in amount by half
Chemical name of drugs - Answer✔the name of the medication that reflects its chemical
composition and molecular structure (ex. isobutylphenylpropanoic acid)
Generic name (nonproprietary name) - Answer✔Name given to a medication by the United
States Adopted Names Council (ex. ibuprofen)
Trade name - Answer✔Proprietary name of a drug assigned by the manufacturer; also called
the brand name or product name.
Rights of Safe Medication Administration - Answer✔Right client/patient
Right medication/drug
Right dose
Right time
Right route
Right documentation
Right client education
Right to refuse
Right assessment
Right evaluation
Types of Analgesic Agents - Answer✔Opioids
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Narcotic Antagonists
Antipyretic
NSAIDs
etc.
Opioid Prototype - Answer✔morphine
Action of Morphine - Answer✔Binds to opioid receptors (Mu & Kappa) in the brain and spinal
cord
Indications for Morphine - Answer✔prevent/ relieve severe acute or chronic pain; before,
during and after surgery; before and during diagnostic procedures; labor & delivery
Adverse Effects of Morphine - Answer✔Respiratory depression
Orthostatic hypotension
Excessive Sedation
Constipation/ Urinary Retention
Cough suppression
Biliary colic
Nursing Implications of Morphine - Answer✔watch for s/sx of toxicity: Severe respiratory
depression; coma; pinpoint pupils
General principles of Morphine - Answer✔Metabolized: liver; Excreted: urine, bile; T1/2: 1.5-2
hours
Routes:PO, IV, IM, SUBQ, Intrathecal, epidural
MORPHINE IS THE FIRST CHOICE FOR SEVERE PAIN
No ceiling
Regular schedule
Narcotic Antagonist Prototype - Answer✔Naloxone (Narcan)
Action of Naloxone (Narcan) - Answer✔Block effects of opioids
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Indications of Naloxone (Narcan) - Answer✔Reversal of signs or opioid excess
Adverse Effects of Naloxone (Narcan) - Answer✔Dysrhythmias
HTN
Hypotension
N/V
Nursing Implications for Naloxone (Narcan) - Answer✔Likely to need repeated injections
Titrate with care to avoid acute withdrawal
General Principles of Naloxone (Narcan) - Answer✔Onset: within minutes of parenteral
administration (almost immediately if IV)
T1/2: 30 to 81 minutes
Metabolized in liver
Excreted by kidney
Prostaglandin inhibitors - Answer✔NSAIDs. Medications that act on prostaglandins, compounds
that regulate muscle contractions (& Acetaminophen)
Antipyretic Prototype - Answer✔Acetaminophen (Tylenol)
Action of Acetaminophen (Tylenol) - Answer✔Inhibits prostaglandin synthesis in central
nervous system
Indications of Acetaminophen - Answer✔Relief of mild pain or fever, headache, muscle aches
Adverse Effects of Acetaminophen - Answer✔HEPATOXICITY
Nursing Implications of Acetaminophen - Answer✔Treatment of poisoning"
Acetylcysteine
NSAID Prototype(s) - Answer✔Ibuprofen (Advil/Motrin) and Aspirin
Action of Aspirin (ASA) - Answer✔inactivation of Cox-1 and Cox-2; inhibits formation of
prostaglandins
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