PCOL 838 Midterm Exam 2025 Graded
A+ Questions with 100% Correct
Answers
what are the four major islet cell types and their functions? - - beta cells = secrete insulin (60%)
- alpha cells = secrete glucagon (30%)
- delta cells = secrete somatostatin (10%)
- pancreatic polypeptide secreting cell (1%)
what is the effect of alpha cells (glucagon) on other islet cells? - it stimulates beta cells (insulin) and
delta cells (somatostatin)
what is the effect of delta cells (somatostatin) on other islet cells? - it inhibits beta cells (insulin) and
alpha cells (glucagon)
what is the effect of beta cells (insulin) on other islet cells? - it inhibits alpha cells (glucagon)
what do beta cells secrete?
a. insulin
b. glucagon
c. somatostatin - a. insulin
what do alpha cells secrete?
a. insulin
, b. glucagon
c. somatostatin - b. glucagon
what do delta cells secrete?
a. insulin
b. glucagon
c. somatostatin - c. somatostatin
what does the presence of C peptide mean? - it means insulin is being made
what is the effect of insulin responsive cells (IRCs) on the body? - - liver and muscle = decrease
gluconeogenesis and glycogenolysis
- adipocytes = increased lipogenesis and adipogenesis
how is glucose transported into the cell? - GLUT4 transporter fuses with the membrane and causes
glucose uptake
what is the end result of PI3K signaling?
a. necrosis
b. phagocytosis
c. apoptosis
d. entosis - c. apoptosis
A+ Questions with 100% Correct
Answers
what are the four major islet cell types and their functions? - - beta cells = secrete insulin (60%)
- alpha cells = secrete glucagon (30%)
- delta cells = secrete somatostatin (10%)
- pancreatic polypeptide secreting cell (1%)
what is the effect of alpha cells (glucagon) on other islet cells? - it stimulates beta cells (insulin) and
delta cells (somatostatin)
what is the effect of delta cells (somatostatin) on other islet cells? - it inhibits beta cells (insulin) and
alpha cells (glucagon)
what is the effect of beta cells (insulin) on other islet cells? - it inhibits alpha cells (glucagon)
what do beta cells secrete?
a. insulin
b. glucagon
c. somatostatin - a. insulin
what do alpha cells secrete?
a. insulin
, b. glucagon
c. somatostatin - b. glucagon
what do delta cells secrete?
a. insulin
b. glucagon
c. somatostatin - c. somatostatin
what does the presence of C peptide mean? - it means insulin is being made
what is the effect of insulin responsive cells (IRCs) on the body? - - liver and muscle = decrease
gluconeogenesis and glycogenolysis
- adipocytes = increased lipogenesis and adipogenesis
how is glucose transported into the cell? - GLUT4 transporter fuses with the membrane and causes
glucose uptake
what is the end result of PI3K signaling?
a. necrosis
b. phagocytosis
c. apoptosis
d. entosis - c. apoptosis
