Guaranteed Answers (Verified)
Asthma Treatment Step 1 (Ages 12 and Older) - Symptoms driven treatment with low dose ICS-
fomoterol
Asthma Treatment Step 2 (Ages 12 and Older) - Low-dose ICS fomorteol as needed
Or
Daily low-dose maintenance ICS
Asthma Treatment Step 3 (Ages 12 and Older) - Low-dose maintenance ICS-fomoterol
Or
Low-dose ICS and maintenance LABA
Asthma Treatment Step 3 (Ages 12 and Older) - Medium dose ICS-formoterol
Or
Medium/high dose ICA and LABA
Asthma Treatment Step 5 (Ages 12 and Older) - Add on LAMA and referral to a specialist for
phenotyping (anti-IgE, anti IL5/5R and IL4R), consider high dose ICS formiterol
Stepwise approach for managing asthma treatment Step 1 (Ages 6-11) - Low dose ICS taken
whenever SABA is taken
What is the MOA of Omalizumab? - Monoclonal antibody directed against IgE, inhibiting the allergic
release of inflammatory mediators
What is the MOA of Mepolizumab? - Monoclonal antibody against IL-5, reducing Eosinophil
inflammation
Mepolizumab is a sub Q Injection that is for people ages 12 and up, True or False? - True
What is the MOA for Benralizumab? - Monoclonal antibody against IL-5 receptor, reducing
eosinophilic inflammation
, Reslizumab and Mepolizumab have the same mechanism of action, what is the difference in
medication administration? - Reslizumab is IV when Mepolizumab is Sub Q
What's the MOA of Dupilumab? - Monoclonal antibody against IL-4 receptors
Albuterol and Terbutaline are what drug class? - SABA
What is the MOA of Terbutaline? - Beta 2 Agonist - provides quick reload of asthma symptoms by
relaxing bronchial smooth muscle
Albuterol should be frequently and at its highest dose, True or False? - False, should only be used as
needed and at the lowest dose
Name two LABAs - Salmeterol
Formoterol
What category of drug does Formoterol need to be paired with? - Inhaled corticosteroids (ICS)
Which inhaled corticosteroids does NOT end in -one? - Budesonide
What are some side effects of ICS? - Oralpharyngeal Candidas
Dysphonia
Osteoporosis (long term use)
What is the MOA of Zarfirlukast - Blocks Leukotriene receptors to reduce inflammation and
broncoconstriction
Tiotropium is what class - Inhaled M3 Receptor Antagonist (LAMA)
During what step(s) would Tiotropium be used to control asthma? - Add on option for Step 5 (non
preferred step 4) for patients with uncontrolled asthma despite ICS-LABA