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Creams and Ointments Notes

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PDF containing notes from Creams and Ointments lecture, from Molecules to Medicine module

Institution
University Of Portsmouth (UoP)
Course
Molecules to Medicine

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Creams and Ointments
Created @January 28, 2025 12:57 PM

Class Molecules to Medicine

Pharmaceutical Emulsions

Oral/rectal/topical oil administration and oil soluble drugs

Formulation of oil and water- soluble drugs together

Improve palatability of oils by disguising taste and general oiliness

More absorption of oil and oil-soluble drugs in intestinal walls

Intramuscular vaccination of vaccine that’s water soluble, results in slower
drug release and increased antibody response

TPN- Method of nutrition administration as a last resort




Emulsion Types

Oil in water

For oral and intravenous administration

Topical application

Less greasy

Easily washed off

Acceptable in cosmetics

Water in Oil

Intramuscular



Creams and Ointments 1

, Topical can be easily rubbed on to skin

Hydrates skin

Water in oil in water

Delayed action




Emulsifying Agents

Emulsifying agent solubility

More soluble in water than oil in water

More soluble in oil than water in oil

Properties

No colour, odour or taste

Not toxic

Non- irritant

Creates stable emulsion at a low conc

PHASE INVERSION OCCURS IF SOLUBILITY IS ALTERED AFTER A
CHEMICAL IS ADDED




Natural Emulsifying Agents

Polysaccharides

Acacia

Creates thick film between oil and water preventing Coalescence
(Merging of substances)

Tragacanth

Viscosity increase




Creams and Ointments 2
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Document information

Uploaded on
February 3, 2025
Number of pages
6
Written in
2024/2025
Type
Class notes
Professor(s)
Marta roldo
Contains
All classes

Subjects

  • creams
  • emulsions
  • emulsifying agents
  • ingredients
  • antioxidants
  • ointments
  • revision notes
  • molecules to medicine
  • lecture notes
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