NYU Nursing Pharmacology
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Pharmacokinetics - answer MOTION:
How medications are absorbed, distributed and metabolized into cells ->
tissues -> organs. Also how they are excreted.
What is pharmacodynamics? - answer ACTION:
Effects of drugs on the body. How drugs mimic the body's own chemical
receptors.
What is pharmacogenetics? - answer How an individual's genetics
influence their response to a drug.
What are the phases of pharamcokinetics? - answer 1. Absorption
2. Distribution
3. Metabolism
4. Excretion
What happens during absorption? - answer The drug moves through the GI
tract into the bloodstream.
What happens during a drug's distribution? - answer 1. Some metabolites
of the drug will bind to proteins (typically albumin). This causes inactivity.
2. Some metabolites will be free and unbound. These are active.
, - Most drugs are 89% likely to bind,whereas less than 30% low protein
bound.
How does hypoalbuminemia affect drug distribution? - answer Lower
concentrations of these plasma proteins causes an excess availability of
the free drug to be active. This can cause toxicity.
As a nurse how can we prevent drug toxicity? - answer Always check the
plasma protein & albumin content of a patient's blood sample.
- It is important to note that patients with liver and kidney issues are at a
higher likelihood to develop drug toxicity.
What are examples of changes in blood flow that will interrupt a drug's
distribution, further leading to drug toxicities? - answer - Wounds,
abscesses, exudates, and tumors.
- Drug based affinities: some drugs can accumulate in fat, bone, liver
muscle, and eye tissue.
What factors can influence influence absorption? - answer - Circulation
- Pain,stress
- Food texture, fat content, temp
- BIG ONE: pH (blood pH can influence the drug's ability to properly work
within the blood)
- Route of administration.
How does a drug move within the GI tract to the liver? - answer Via the
hepatic portal vein.
What is metabolism? - answer - Metabolism is the process by which the
body inactivates or biotransforms drugs.
latest update with complete
verified solutions (graded A+)
Save
Pharmacokinetics - answer MOTION:
How medications are absorbed, distributed and metabolized into cells ->
tissues -> organs. Also how they are excreted.
What is pharmacodynamics? - answer ACTION:
Effects of drugs on the body. How drugs mimic the body's own chemical
receptors.
What is pharmacogenetics? - answer How an individual's genetics
influence their response to a drug.
What are the phases of pharamcokinetics? - answer 1. Absorption
2. Distribution
3. Metabolism
4. Excretion
What happens during absorption? - answer The drug moves through the GI
tract into the bloodstream.
What happens during a drug's distribution? - answer 1. Some metabolites
of the drug will bind to proteins (typically albumin). This causes inactivity.
2. Some metabolites will be free and unbound. These are active.
, - Most drugs are 89% likely to bind,whereas less than 30% low protein
bound.
How does hypoalbuminemia affect drug distribution? - answer Lower
concentrations of these plasma proteins causes an excess availability of
the free drug to be active. This can cause toxicity.
As a nurse how can we prevent drug toxicity? - answer Always check the
plasma protein & albumin content of a patient's blood sample.
- It is important to note that patients with liver and kidney issues are at a
higher likelihood to develop drug toxicity.
What are examples of changes in blood flow that will interrupt a drug's
distribution, further leading to drug toxicities? - answer - Wounds,
abscesses, exudates, and tumors.
- Drug based affinities: some drugs can accumulate in fat, bone, liver
muscle, and eye tissue.
What factors can influence influence absorption? - answer - Circulation
- Pain,stress
- Food texture, fat content, temp
- BIG ONE: pH (blood pH can influence the drug's ability to properly work
within the blood)
- Route of administration.
How does a drug move within the GI tract to the liver? - answer Via the
hepatic portal vein.
What is metabolism? - answer - Metabolism is the process by which the
body inactivates or biotransforms drugs.
