NURS 251 Portage Study Guide 2
x x x x x x
x
inflammatory xmediators x- xend xresults xof xinflammation, xhelp xus xto xheal, xbut xcause
xpain x
x x
and xswelling xalong xthe
xway
x
--pain, xheat, xredness,
xswelling
x
corticosteroids x- xgroup xof xsteroidal xhormones. x
x
cortisol x- xprototypical, xnaturally xoccuring x(endogenous) xcorticosteroid x x-
produced xin xthe xouter xpart x(cortex) xof xthe xadrenal xglands xthat xsit xon xtop xof
xthe xkidneys x
-modulate xglucose xlevels xand xbody xresponses xto xstress x
-temper xthe ximmune xfunction, xand xdecrease xinflammatory xresponse x
x
eicosanoids x- xlocal xhormones xthat xare xderived xfrom xlipid xmolecules xon xthe xcell
xmembrane xof xvirtually xall xbody xcells x x
--involved xin xregulating xa xnumber xof xdifferent xphysiologic xprocesses xfrom xbirth
xand xBP, xto xinflammation xand xpain x
x
corticosteroids xare xbetter xantiinflammatories xthan xCOX-inhibitors x(like xaspirin)
xbecause xthey xinhibit xall xaspects xof xthe x__________ x_____ x_________ x-
xarachidonic xacid xcascade x
x
because xthey xwork xupstream xof xarachidonic xacid, xcorticosteroids xalso
xinhibit..... x-
x
leukotrienes xproduced xfrom xthe xlipoxygenase
xenzyme
x
x
over xa xlong xperiod xof xuse, xpatient xtaking xcorticosteroids xactually
xdevelop xa
characteristic xbody xhabitus xand xthe xperson xis xsaid xto xbe x_______ x-
xcushinoid
x
corticosteroids xhave xsystemic xmajor xside xeffects, xso xwe xtry xto xuse xthem x______
x__ x
x
_______ x- xregionally xor
xlocally
x
cortisone x- xa xsynthetic xderivative xof xthe xnatural xcorticosteroid xhormone xcortisol x
x
Cortenema x- xhydrocortisone xis xformulated xin xprescription xstrength xas xan
xenema x
x x
--for xuse xin xcases xof xCrohn's xdisease/ulcerative
xcolitis
x
--
corticosteroid
x
, prednisone x- xone xof xthe x most popular,
x x potent
xcorticosteroids x
x x
--usually xadministered
xorally
x
--
corticosteroid
x
hydrocortisone x- xcan xbe xfound xin xOTC xcreams x
--you xmight xfind xthem xto xbe xtoo xweak, xand xmay xneed xprescription xstrength
xsteroids x--corticosteroid x
x
methylprednisolone x- xSolu-Medrol x x
for xIV xadministartion xin xemergency xcases, xsuch xas xtreatment xof xanaphylaxis x x--
corticosteroid x
x
triamcinolone x- xKenalog x x
popular xprescription xstrength xcreams xand xointments x x
--corticosteroid x
x
betamethasone x- x popular x prescription x strength x creams x and
xointments x
x
--
corticosteroid
x
estradiol x- xEz x
predominant xestrogen xin xnonpregnant xwomen, xproduced xprimarily xby xdeveloping
xovarian xfollicles x
x
x
testosterone x- xmale xsex
xsteroid
most ximportant xmale xandrogen
xhormone
x
dihydrotestosterone x- xmale xsex xsteroid
xmost ximportant xmale xandrogen xhormone x
x
(DHT) x
x
x x
Dianabol x- x--
methandrostenolone
x x
synthetic xdrug xof
xabuse
first xanabolic xsteroid xin xthe xUS, xdeveloped xfor xolympic
xathletes
x
Recombinant xHuman xGrowth xHormone x- xr-
HGH
x x
produced xas xthe xdrug
xGenotropin
x
--nonsteroid xprotein xbasedx
x
xhormone
x x x x x x
x
inflammatory xmediators x- xend xresults xof xinflammation, xhelp xus xto xheal, xbut xcause
xpain x
x x
and xswelling xalong xthe
xway
x
--pain, xheat, xredness,
xswelling
x
corticosteroids x- xgroup xof xsteroidal xhormones. x
x
cortisol x- xprototypical, xnaturally xoccuring x(endogenous) xcorticosteroid x x-
produced xin xthe xouter xpart x(cortex) xof xthe xadrenal xglands xthat xsit xon xtop xof
xthe xkidneys x
-modulate xglucose xlevels xand xbody xresponses xto xstress x
-temper xthe ximmune xfunction, xand xdecrease xinflammatory xresponse x
x
eicosanoids x- xlocal xhormones xthat xare xderived xfrom xlipid xmolecules xon xthe xcell
xmembrane xof xvirtually xall xbody xcells x x
--involved xin xregulating xa xnumber xof xdifferent xphysiologic xprocesses xfrom xbirth
xand xBP, xto xinflammation xand xpain x
x
corticosteroids xare xbetter xantiinflammatories xthan xCOX-inhibitors x(like xaspirin)
xbecause xthey xinhibit xall xaspects xof xthe x__________ x_____ x_________ x-
xarachidonic xacid xcascade x
x
because xthey xwork xupstream xof xarachidonic xacid, xcorticosteroids xalso
xinhibit..... x-
x
leukotrienes xproduced xfrom xthe xlipoxygenase
xenzyme
x
x
over xa xlong xperiod xof xuse, xpatient xtaking xcorticosteroids xactually
xdevelop xa
characteristic xbody xhabitus xand xthe xperson xis xsaid xto xbe x_______ x-
xcushinoid
x
corticosteroids xhave xsystemic xmajor xside xeffects, xso xwe xtry xto xuse xthem x______
x__ x
x
_______ x- xregionally xor
xlocally
x
cortisone x- xa xsynthetic xderivative xof xthe xnatural xcorticosteroid xhormone xcortisol x
x
Cortenema x- xhydrocortisone xis xformulated xin xprescription xstrength xas xan
xenema x
x x
--for xuse xin xcases xof xCrohn's xdisease/ulcerative
xcolitis
x
--
corticosteroid
x
, prednisone x- xone xof xthe x most popular,
x x potent
xcorticosteroids x
x x
--usually xadministered
xorally
x
--
corticosteroid
x
hydrocortisone x- xcan xbe xfound xin xOTC xcreams x
--you xmight xfind xthem xto xbe xtoo xweak, xand xmay xneed xprescription xstrength
xsteroids x--corticosteroid x
x
methylprednisolone x- xSolu-Medrol x x
for xIV xadministartion xin xemergency xcases, xsuch xas xtreatment xof xanaphylaxis x x--
corticosteroid x
x
triamcinolone x- xKenalog x x
popular xprescription xstrength xcreams xand xointments x x
--corticosteroid x
x
betamethasone x- x popular x prescription x strength x creams x and
xointments x
x
--
corticosteroid
x
estradiol x- xEz x
predominant xestrogen xin xnonpregnant xwomen, xproduced xprimarily xby xdeveloping
xovarian xfollicles x
x
x
testosterone x- xmale xsex
xsteroid
most ximportant xmale xandrogen
xhormone
x
dihydrotestosterone x- xmale xsex xsteroid
xmost ximportant xmale xandrogen xhormone x
x
(DHT) x
x
x x
Dianabol x- x--
methandrostenolone
x x
synthetic xdrug xof
xabuse
first xanabolic xsteroid xin xthe xUS, xdeveloped xfor xolympic
xathletes
x
Recombinant xHuman xGrowth xHormone x- xr-
HGH
x x
produced xas xthe xdrug
xGenotropin
x
--nonsteroid xprotein xbasedx
x
xhormone