Maryville Pharmacology Exam 1 Questions
With Correct Answers 100% Verified.
What are the 5 WHO prescribing guidelines? - Answer✔1. define the pt's problem
2. Specify therapeutic objectives
3. choose which drug or treatment is needed
4. Write the Rx and start tx
5. Educate and counsel the pt
6. monitor effect of treatment
WHO rx guideline 1 - Answer✔Define the pt's problem . This forms the basis for choosing and
rx-ing the correct treatment.
Consultation should include: complaints, symptoms, diagnosis and relevant characteristics like
co-morbidities, co-medication, pregnancy, drug allergies
WHO rx guideline 2 - Answer✔Specify the therapeutic objective. What needs to be treated?
WHO rx guideline 3 - Answer✔3a. select the p-drug (prescribers personal drug of first choice for
the indication.)
3b. Is the p-drug appropriate? checking for contraindications, interactions, pregnancy, allergies,
etc.
WHO rx guideline 4 - Answer✔Write rx and start the treatment.
WHO rx guideline 5 - Answer✔Educate and counsel the pt. Intructions and warnings about the
tx.
WHO rx 6 - Answer✔Monitor the treatment.
Coreg (Carvedilol) - Answer✔*beta blocker used to treat mild to severe CHF, left ventricular
dysfunction following MI, HTN.
*works by causing vasodilation to the peripheral vasculature to decrease the workload on the
heart.
*Non selective beta blocker and Alpha-1 blocker
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*3rd generation beta blocker
*particularly useful in African Americans
*Dose: 0.625 mg-25mg PO BID with food
*administering with food helps prevent postural hypotension
*Education: don't skip doses, take with food
hypersensitivty reactions: mnemonic ACID - Answer✔1. A-allergic
2.C-cytotoxic
3.I- Immune complex deposition
4. D-delayed
Type I hypersensitivity - Answer✔A-allergic
*IgE mediated- quick onset after exposure
*production of IgE after antigen exposure.
*urticaria, wheezing, rhinitis, anaphylaxis
Type II hypersensitivity - Answer✔C-cytotoxic
*cytotoxic/antibody mediated
* drug binds to RBCs and is recognized by antibody-usually IgG
*complement and cytotoxic T cells are activated
*Rare response
Type III hypersensitivity - Answer✔I-immune complex/IgG/IgM mediated
*antibodies are formed against soluble antigens. ANtigen-antibody complexes are deposited in
tissues such as joints and lungs.
*cause serum sickness. Ex: ceclor (antibiotic)
Type IV hypersensitivity - Answer✔D-delayed- delayed or cell mediated
*cytotoxic T cells are activated
*poison ivy, latex, etc
*causes contact dermatitis
*cytokine storm if there is repeated exposure
Grapefruit juice - Answer✔*increases drug toxicity
*don't drink with SSRIs, calcium channel blockers, statins, benzos
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