DPC Final - Psychiatry Exam With
Correct Solution
What is Schizophrenia? - ANSWER Syndrome of disorganized and bizarre thoughts,
delusions, hallucinations, inappropriate affect, and impaired psycho-social functioning.
Etiology of Schizophrenia - ANSWER Unknown, usually various abnormalities in brain
structure/function.
Strong genetic component
Positive Symptoms - ANSWER Suspiciousness, Delusions, Hallucination, Conceputal
disorganizations
Negative Symptoms - ANSWER affective flattening, anhedonia, avolition
Cognitive Symptoms - ANSWER Impaired attention, impaired memory, impaired
executive function
Atypical Antipsychotics Counseling - ANSWER -Treat both +/- symptoms
-May take several weeks to see full benefit
-Do not stop taking abruptly
-May get dizzy or drowsy (cautions with driving or sitting up quickly)
-Avoid alcohol
-Can reduce response of body to hot or cold
-Contact PCP if you have increased hunger or thirst
-Do not treat yourself for colds, diarrhea, or allergies
-Watch for worsening depression or mood changes.
Monitoring for Antipsychotics - ANSWER -Blood glucose
-LFTs
-Neurologic Function
-Serum cholesterol profile
-Weight
, Seroquel (Quetiapine) - ANSWER -Liver metabolism (dose adjust in liver impairment)
-Pregnancy C
-Check vision at baseline and 6 months, esp. cataracts
-Use: schizophrenia and bipolar disorder
-Administer XR w/o food or with 300 calories
-If patient off for more than 1 week, start initial titration again
Zyprexa (Olanzapine) - ANSWER -Use: schizophrenia, psychotic disorders, bipolar
disorder
-ODT, tab, IM
-Pregnancy C
Risperdal (Risperidone) - ANSWER -Tab, ODT, long-acting injection, oral solution
-Pregnancy C
Abilify (Aripiprazole) - ANSWER -Discmelt, tab, oral solution, IM
-Use: schizophrenia, bipolar
-Pregnancy C
-May be taken with or without food
Clozaril (Clozapine) - ANSWER -Tab, ODT
-Low EPS
-Good for patients refractive to other treatments
-BBW: agranuloctytosis, seizures, myocarditis, CV/respiratory, dementia
-Monitor WBC and hold if WBC <3000 or ANC<1000
-Monitor WBC/ANC Q week x 6 months, Q 2 weeks x 6 months, then monthly
Depressive Disorders - ANSWER A disorder of mood in which the individual experiences
one or more major depressive episodes.
Can occur at any age, highest age 25-44 years
Etiology of Depression - ANSWER Complex, includes social, developmental, biological.
Changes in monoamine NT (NE, 5-HT, DA)
Drugs that Can Cause Depression - ANSWER Antihypertensives
Correct Solution
What is Schizophrenia? - ANSWER Syndrome of disorganized and bizarre thoughts,
delusions, hallucinations, inappropriate affect, and impaired psycho-social functioning.
Etiology of Schizophrenia - ANSWER Unknown, usually various abnormalities in brain
structure/function.
Strong genetic component
Positive Symptoms - ANSWER Suspiciousness, Delusions, Hallucination, Conceputal
disorganizations
Negative Symptoms - ANSWER affective flattening, anhedonia, avolition
Cognitive Symptoms - ANSWER Impaired attention, impaired memory, impaired
executive function
Atypical Antipsychotics Counseling - ANSWER -Treat both +/- symptoms
-May take several weeks to see full benefit
-Do not stop taking abruptly
-May get dizzy or drowsy (cautions with driving or sitting up quickly)
-Avoid alcohol
-Can reduce response of body to hot or cold
-Contact PCP if you have increased hunger or thirst
-Do not treat yourself for colds, diarrhea, or allergies
-Watch for worsening depression or mood changes.
Monitoring for Antipsychotics - ANSWER -Blood glucose
-LFTs
-Neurologic Function
-Serum cholesterol profile
-Weight
, Seroquel (Quetiapine) - ANSWER -Liver metabolism (dose adjust in liver impairment)
-Pregnancy C
-Check vision at baseline and 6 months, esp. cataracts
-Use: schizophrenia and bipolar disorder
-Administer XR w/o food or with 300 calories
-If patient off for more than 1 week, start initial titration again
Zyprexa (Olanzapine) - ANSWER -Use: schizophrenia, psychotic disorders, bipolar
disorder
-ODT, tab, IM
-Pregnancy C
Risperdal (Risperidone) - ANSWER -Tab, ODT, long-acting injection, oral solution
-Pregnancy C
Abilify (Aripiprazole) - ANSWER -Discmelt, tab, oral solution, IM
-Use: schizophrenia, bipolar
-Pregnancy C
-May be taken with or without food
Clozaril (Clozapine) - ANSWER -Tab, ODT
-Low EPS
-Good for patients refractive to other treatments
-BBW: agranuloctytosis, seizures, myocarditis, CV/respiratory, dementia
-Monitor WBC and hold if WBC <3000 or ANC<1000
-Monitor WBC/ANC Q week x 6 months, Q 2 weeks x 6 months, then monthly
Depressive Disorders - ANSWER A disorder of mood in which the individual experiences
one or more major depressive episodes.
Can occur at any age, highest age 25-44 years
Etiology of Depression - ANSWER Complex, includes social, developmental, biological.
Changes in monoamine NT (NE, 5-HT, DA)
Drugs that Can Cause Depression - ANSWER Antihypertensives
