ABSITE - CRITICAL CARE QUESTIONS
WITH CORRECT ANSWERS 2025
AllMareMpotentialMcausesMofMcardiogenicMshockMexcept:
-MMyocardialMinfarction.
-MPericardialMtamponade.
-MTensionMpneumothorax.
-MCardiacMarrhythmias.
-MExcessiveMpreload.M-MCORRECTMANSWERM-ExcessiveMpreload.
(ExcessiveMpreloadMisMtypicallyMnotMaMcauseMofMcardiogenicMshock,MbutMisMaMresultMofMcardiogenicMshock.
)
AM60-year-
oldMmanMhasManMarterialMPOMofM60MmmMHgMwhenMtheMcalculatedMalveolarMPOMisM94MmmMHg.MThisMdiffer
enceMisMmostMcommonlyMdueMtoM-MCORRECTMANSWERM-aMventilation-perfusionMmismatch
oxygenMdeliveryMandMconsumptionM-MCORRECTMANSWERM--
MUnderMnormalMcircumstances,MapproximatelyM20%MtoM30%MofMtheMoxygenMdeliveredMtoMtheMcapillaryMb
edMisMextractedMbyMtheMtissues.
-
MInMconditionsMofMdecreasedMdeliveryMofMoxygen,MtissuesMareMcapableMofMextractingMupMtoM50%MtoM60%M
ofMtheMoxygenMcontentMinMtheMcapillaryMblood.
-MWhenMcellularMoxygenMsupplyMdoesMnotMmeetMdemand,ManaerobicMrespirationMresults.
(TheMvariablesMinMtheMequationMforMtheMdeliveryMofMoxygenMareMcardiacMoutput,MhemoglobinMlevel,Moxyg
enMsaturationMofMhemoglobin,MandMtheMpartialMpressureMofMoxygenMdissolvedMinMblood.MIncreasesMinMth
eMfirstMthreeMvariablesMallMyieldMsignificantMincreasesMinMtheMtotalMamountMofMoxygenMcarriedMbyMblood.M
TheMpartialMpressureMofMoxygenMisMmultipliedMbyMaMfactorMofM0.003,Mhowever,MandMthereforeMhasMaMmin
isculeMcontributionMtoMtheMtotalMoxygenMcontent.)
DopamineMatMdosesMofM5MtoM10Mμg/kg/minM-MCORRECTMANSWERM-hasMaMlargelyMinotropicMactionMprofile
(DopamineMhasMaMdose-
dependentMactionMprofile.MAtM3MtoM5Mμg/kg/min,MitsMactionsMareMlargelyMtoMincreaseMrenalMbloodMflow.M
AtMdosesMofM5MtoM10Mμg/kg/min,MitMlargelyMactsMtoMstimulateMmyocardialMβMreceptorsMandMhasManMinotr
,opicMeffect.MAtMdosesMgreaterMthanM10Mμg/kg/min,MitMstimulatesMαMreceptorsMandMhasMaMchronotropicMe
ffect.)
AsMoxygenMdeliveryMincreasesMonMtheMflatMhorizontalMportionMofMtheMoxygenMconsumption-
deliveryMcurveM-MCORRECTMANSWERM-OxygenMconsumptionMremainsMtheMsame
(OnMtheMflatMhorizontalMportionMofMtheMoxygenMconsumption-
deliveryMcurve,MoxygenMdeliveryMmeetsMcellularMdemandMofMoxygen;MasMoxygenMdeliveryMincreases,Moxyg
enMconsumptionMremainsMtheMsame.)
MostMdisorganizedMventricularMarrhythmiasM(frequentMPVCs,MventricularMfibrillation)MareMcausedMbyM-
MCORRECTMANSWERM-MetabolicMderangements.
(MostMdisorganizedMventricularMarrhythmiasMareMcausedMbyMsomeMsortMofMmetabolicMderangementMsuc
hMasMischemiaMorMmagnesiumMorMpotassiumMdeficiencies.MTheseMabnormalitiesMareMnotMwellMtreatedMby
MantiarrhythmicMmedications.)
TheMbestMmanagementMforMaMpatientMwithMaMposteriorMkneeMdislocationM-MCORRECTMANSWERM-
Arteriogram.
(TheMpatientMmayMhaveMfairlyMnormalMpulsesMandMstillMhaveManMintimalMinjuryMofMtheMpoplitealMarteryMth
atMisMsimilarMtoMtheMintimalMdisruptionMthatMcanMbeMseenMinMaorticMisthmusMinjury.)
theMpossibleMetiologiesMofMmultiorganMfailureM-MCORRECTMANSWERM--
MAnticytokineMantibodiesMhaveMshownMtherapeuticMpromiseMinManimalMstudies.
-MEvidenceMhasMshownMthatMintestinalMmucosaMisMmadeMpermeableMbyMsepsis.
-MTheM"two-
hit"MhypothesisMpostulatesMthatMafterMmountingManMappropriateMresponseMtoMsomeMphysiologicMinsult,Mt
heMpatientMisMleftMwithMaMprimedMimmuneMsystemMwhichMmanifestsManMexaggeratedMimmuneMresponseM
toMaMsecondMchallenge.
-
MTheMearlyMstagesMafterMinjuryMactuallyMappearMtoMconsistMofManMimmediateMproinflammatoryMstateMasMt
heMorganismMtriesMtoMaddressMtheMphysiologicMinsult.MWhenMproperlyMmodulated,MthisMisManMappropriat
eMfunction.MWhenMoverexpressed,MthisMproinflammatoryMstateMleadsMtoMtheMsystemicMinflammatoryMres
ponseMsyndrome.MLater,Manti-
inflammatoryMandMimmunosuppressiveMmechanismsMareMbroughtMintoMplayMtoMbringMtheMorganismMbac
kMtoMhomeostasis.MIfMovermanifested,MtheyMcanMleadMtoMaMrelativeMgeneralizedMimmunosuppressionMan
dMlateMincidentsMofMsepsisMorMmultiorganMfailure.
,compensatoryMmechanismsMinMshockM-MCORRECTMANSWERM-
AntidiureticMhormoneMcausesMtheMreabsorptionMofMfreeMwaterMbyMtheMkidneyMandMhasMvasoconstrictiveM
properties.
(AntidiureticMhormoneMisMreleasedMfromMtheMposteriorMpituitaryMwhereMitMstimulatesMfreeMwaterMretenti
onMbyMtheMkidneyMandMactsMasMaMpowerfulMvasoconstrictor.)
AM71-year-
oldMmanMwithMcolonMcancerMisMinMtheMintensiveMcareMunitMfollowingMaMleftMhemicolectomy.MHisMbloodMp
ressureMisM72/38MmmMHg,MpulseMrateMisM114/min,MrespiratoryMrateMisM23/min,MandMoxygenMsaturationMis
M94%MonM2MLMofMoxygenMbyMnasalMcannulae.MAMpulmonaryMarteryMcatheterMshowsMaMcentralMvenousMpre
ssureMofM8McmMHMO,MaMpulmonaryMarteryMpressureMofM22/8MmmMHg,MaMpulmonaryMarteryMwedgeMpressu
reMofM6MmmMHg,MandMaMcardiacMoutputMofM3.4ML/min.MTheMnextMstepMinMmanagementMshouldMbeMtheMin
travenousMadministrationMofM-MCORRECTMANSWERM-aMfluidMbolus
pulmonaryMarteryMcathetersM-MCORRECTMANSWERM-
AllowMaccurateMapproximationMofMleftMatrialMpressure.
TheMmagnitudeMofMaMleft-to-rightMshuntMinMtheMpresenceMofManMASDMisMdeterminedMbyM-
MCORRECTMANSWERM-DifferenceMinMcomplianceMbetweenMleftMandMrightMventricles.
(TheMbloodMwillMtendMtoMfillMtheMmoreMcompliantMventricleMwhichMwillMusuallyMbeMtheMright,MuntilMchroni
cMpulmonaryMhypertensionMyieldsMrightMventricularMhypertrophy.)
ComparedMtoMconventionalMventilationM(endotrachealMintubation),MnoninvasiveMventilationM(mask,Mconti
nuousMpositiveMairwayMpressure)MisM-MCORRECTMANSWERM-
contraindicatedMinMhemodynamicallyMunstableMpatients
AccordingMtoMtheMAmericanMCollegeMofMChestMPhysicians/SocietyMofMCriticalMCareMMedicineMConsensusM
Conference,MwhichMofMtheMfollowingMareMnotMpartMofMtheMdiagnosticMcriteriaMforMsepsis?M-
MCORRECTMANSWERM-HypotensionMdefinedMasMaMsystolicMbloodMpressureMlessMthanM90MmmMHg.
(SepsisMisMdefinedMasMbacteriologicMevidenceMofMinfectionMsuperimposedMonMaMclinicalMpictureMofMSIRS.M
AccordingMtoMtheMACCP/SCCM,MbyMdefinitionMtheseMpatientsMareMhemodynamicallyMstable.MIfMtheyMshou
ldMbecomeMhemodynamicallyMunstableM(definedMasMaMsystolicMbloodMpressureM<90MmmMHg),MtheMnameM
forMtheMconditionMchangesMtoM"severeMsepsis.")
SIRSM-MCORRECTMANSWERM--MTemperatureMgreaterMthanM38°CMorMlessMthanM36°C.
, -MHeartMrateMgreaterMthanM90Mbpm.
-MRespiratoryMrateMgreaterMthanM22Mbpm
-MWhiteMbloodMcellMcountMgreaterMthanM12,000MorMlessMthanM4,000MandMgreaterMthanM10%Mbands.
abdominalMcompartmentMsyndromeM-MCORRECTMANSWERM-
OnceMdiagnosed,MtreatmentMconsistsMofMreopeningMtheMabdomenMincludingMdoingMsoMatMtheMbedsideMif
Mnecessary.
(TheMpresenceMofManMabdominalMcompartmentMsyndromeMrequiresMdecompressionMofMtheMabdomen.MIf
MtheMpatientMisMtooMunstableMtoMbeMtransportedMtoMtheMoperatingMroom,MtheMabdomenMshouldMbeMpro
mptlyMreopenedMatMtheMbedside.)
carotidMbruitM-MCORRECTMANSWERM-aMmarkerMforMgeneralizedMatherosclerosis
(InMfact,MstudiesMhaveMshownMthatMaMcarotidMbruitMisMaMriskMfactorMforMcoronaryMarteryMdiseaseMandMfut
ureMmyocardialMinfarction.)
alveolarMventilationM-MCORRECTMANSWERM-
TheMalveolarMgasMequationMcharacterizesMtheMpotentialMforMoxygenMuptakeMandMcarbonMdioxideMremoval
.
(TachypneaMatMaMgivenMminuteMventilationMincreasesManatomicMdead-
spaceMventilation,MnotMalveolarMventilation.MMinuteMventilationMisMtheMvolumeMofMgasMthatMisMinspiredMa
ndMexpiredMatMtheMnasopharynxMandMisMdifferentMthanMthatMoccurringMatMtheMalveolusMbyMtheManatomic
Mdead-
spaceMvolume.MAlthoughMarterialMPcoMisMproportionalMtoMalveolarMventilation,MarterialMPoMisMnotMasMitMm
ayMbeMaffectedMbyMphysiologicMshunting,MdiffusionMblock,MandMsoMon.MTheMRQMisMconstantMunderMnorma
lMphysiologicalMconditionsMatM±M0.8;Mhowever,MitMmayMchangeMsubstantiallyMunderMconditionsMsuchMasMa
naerobicMmetabolism,Moverfeeding,MandMsoMon.MBecauseMtheMalveolarMgasMequationMcharacterizesMtheM
partialMpressuresMofMindividualMgasesMwithinMtheMalveolus,MwhichMinMturnMdetermineMtheMindividualMgra
dientsMforMdiffusion,MtheMequationMdoesMcharacterizeMtheMpotentialMforMoxygen/carbonMdioxideMexchang
e.M)
theMfollowingMmayMconstituteMtheMphysiologicalMdeadMspaceMofMtheMrespiratoryMsystemM-
MCORRECTMANSWERM--MEmphysematousMlung.
-MLungMinvolvedMwithMaMpulmonaryMembolus.
-MProximalMtwoMthirdsMsubsegmentalMbronchi.
-MZoneMoneMalveoli.
WITH CORRECT ANSWERS 2025
AllMareMpotentialMcausesMofMcardiogenicMshockMexcept:
-MMyocardialMinfarction.
-MPericardialMtamponade.
-MTensionMpneumothorax.
-MCardiacMarrhythmias.
-MExcessiveMpreload.M-MCORRECTMANSWERM-ExcessiveMpreload.
(ExcessiveMpreloadMisMtypicallyMnotMaMcauseMofMcardiogenicMshock,MbutMisMaMresultMofMcardiogenicMshock.
)
AM60-year-
oldMmanMhasManMarterialMPOMofM60MmmMHgMwhenMtheMcalculatedMalveolarMPOMisM94MmmMHg.MThisMdiffer
enceMisMmostMcommonlyMdueMtoM-MCORRECTMANSWERM-aMventilation-perfusionMmismatch
oxygenMdeliveryMandMconsumptionM-MCORRECTMANSWERM--
MUnderMnormalMcircumstances,MapproximatelyM20%MtoM30%MofMtheMoxygenMdeliveredMtoMtheMcapillaryMb
edMisMextractedMbyMtheMtissues.
-
MInMconditionsMofMdecreasedMdeliveryMofMoxygen,MtissuesMareMcapableMofMextractingMupMtoM50%MtoM60%M
ofMtheMoxygenMcontentMinMtheMcapillaryMblood.
-MWhenMcellularMoxygenMsupplyMdoesMnotMmeetMdemand,ManaerobicMrespirationMresults.
(TheMvariablesMinMtheMequationMforMtheMdeliveryMofMoxygenMareMcardiacMoutput,MhemoglobinMlevel,Moxyg
enMsaturationMofMhemoglobin,MandMtheMpartialMpressureMofMoxygenMdissolvedMinMblood.MIncreasesMinMth
eMfirstMthreeMvariablesMallMyieldMsignificantMincreasesMinMtheMtotalMamountMofMoxygenMcarriedMbyMblood.M
TheMpartialMpressureMofMoxygenMisMmultipliedMbyMaMfactorMofM0.003,Mhowever,MandMthereforeMhasMaMmin
isculeMcontributionMtoMtheMtotalMoxygenMcontent.)
DopamineMatMdosesMofM5MtoM10Mμg/kg/minM-MCORRECTMANSWERM-hasMaMlargelyMinotropicMactionMprofile
(DopamineMhasMaMdose-
dependentMactionMprofile.MAtM3MtoM5Mμg/kg/min,MitsMactionsMareMlargelyMtoMincreaseMrenalMbloodMflow.M
AtMdosesMofM5MtoM10Mμg/kg/min,MitMlargelyMactsMtoMstimulateMmyocardialMβMreceptorsMandMhasManMinotr
,opicMeffect.MAtMdosesMgreaterMthanM10Mμg/kg/min,MitMstimulatesMαMreceptorsMandMhasMaMchronotropicMe
ffect.)
AsMoxygenMdeliveryMincreasesMonMtheMflatMhorizontalMportionMofMtheMoxygenMconsumption-
deliveryMcurveM-MCORRECTMANSWERM-OxygenMconsumptionMremainsMtheMsame
(OnMtheMflatMhorizontalMportionMofMtheMoxygenMconsumption-
deliveryMcurve,MoxygenMdeliveryMmeetsMcellularMdemandMofMoxygen;MasMoxygenMdeliveryMincreases,Moxyg
enMconsumptionMremainsMtheMsame.)
MostMdisorganizedMventricularMarrhythmiasM(frequentMPVCs,MventricularMfibrillation)MareMcausedMbyM-
MCORRECTMANSWERM-MetabolicMderangements.
(MostMdisorganizedMventricularMarrhythmiasMareMcausedMbyMsomeMsortMofMmetabolicMderangementMsuc
hMasMischemiaMorMmagnesiumMorMpotassiumMdeficiencies.MTheseMabnormalitiesMareMnotMwellMtreatedMby
MantiarrhythmicMmedications.)
TheMbestMmanagementMforMaMpatientMwithMaMposteriorMkneeMdislocationM-MCORRECTMANSWERM-
Arteriogram.
(TheMpatientMmayMhaveMfairlyMnormalMpulsesMandMstillMhaveManMintimalMinjuryMofMtheMpoplitealMarteryMth
atMisMsimilarMtoMtheMintimalMdisruptionMthatMcanMbeMseenMinMaorticMisthmusMinjury.)
theMpossibleMetiologiesMofMmultiorganMfailureM-MCORRECTMANSWERM--
MAnticytokineMantibodiesMhaveMshownMtherapeuticMpromiseMinManimalMstudies.
-MEvidenceMhasMshownMthatMintestinalMmucosaMisMmadeMpermeableMbyMsepsis.
-MTheM"two-
hit"MhypothesisMpostulatesMthatMafterMmountingManMappropriateMresponseMtoMsomeMphysiologicMinsult,Mt
heMpatientMisMleftMwithMaMprimedMimmuneMsystemMwhichMmanifestsManMexaggeratedMimmuneMresponseM
toMaMsecondMchallenge.
-
MTheMearlyMstagesMafterMinjuryMactuallyMappearMtoMconsistMofManMimmediateMproinflammatoryMstateMasMt
heMorganismMtriesMtoMaddressMtheMphysiologicMinsult.MWhenMproperlyMmodulated,MthisMisManMappropriat
eMfunction.MWhenMoverexpressed,MthisMproinflammatoryMstateMleadsMtoMtheMsystemicMinflammatoryMres
ponseMsyndrome.MLater,Manti-
inflammatoryMandMimmunosuppressiveMmechanismsMareMbroughtMintoMplayMtoMbringMtheMorganismMbac
kMtoMhomeostasis.MIfMovermanifested,MtheyMcanMleadMtoMaMrelativeMgeneralizedMimmunosuppressionMan
dMlateMincidentsMofMsepsisMorMmultiorganMfailure.
,compensatoryMmechanismsMinMshockM-MCORRECTMANSWERM-
AntidiureticMhormoneMcausesMtheMreabsorptionMofMfreeMwaterMbyMtheMkidneyMandMhasMvasoconstrictiveM
properties.
(AntidiureticMhormoneMisMreleasedMfromMtheMposteriorMpituitaryMwhereMitMstimulatesMfreeMwaterMretenti
onMbyMtheMkidneyMandMactsMasMaMpowerfulMvasoconstrictor.)
AM71-year-
oldMmanMwithMcolonMcancerMisMinMtheMintensiveMcareMunitMfollowingMaMleftMhemicolectomy.MHisMbloodMp
ressureMisM72/38MmmMHg,MpulseMrateMisM114/min,MrespiratoryMrateMisM23/min,MandMoxygenMsaturationMis
M94%MonM2MLMofMoxygenMbyMnasalMcannulae.MAMpulmonaryMarteryMcatheterMshowsMaMcentralMvenousMpre
ssureMofM8McmMHMO,MaMpulmonaryMarteryMpressureMofM22/8MmmMHg,MaMpulmonaryMarteryMwedgeMpressu
reMofM6MmmMHg,MandMaMcardiacMoutputMofM3.4ML/min.MTheMnextMstepMinMmanagementMshouldMbeMtheMin
travenousMadministrationMofM-MCORRECTMANSWERM-aMfluidMbolus
pulmonaryMarteryMcathetersM-MCORRECTMANSWERM-
AllowMaccurateMapproximationMofMleftMatrialMpressure.
TheMmagnitudeMofMaMleft-to-rightMshuntMinMtheMpresenceMofManMASDMisMdeterminedMbyM-
MCORRECTMANSWERM-DifferenceMinMcomplianceMbetweenMleftMandMrightMventricles.
(TheMbloodMwillMtendMtoMfillMtheMmoreMcompliantMventricleMwhichMwillMusuallyMbeMtheMright,MuntilMchroni
cMpulmonaryMhypertensionMyieldsMrightMventricularMhypertrophy.)
ComparedMtoMconventionalMventilationM(endotrachealMintubation),MnoninvasiveMventilationM(mask,Mconti
nuousMpositiveMairwayMpressure)MisM-MCORRECTMANSWERM-
contraindicatedMinMhemodynamicallyMunstableMpatients
AccordingMtoMtheMAmericanMCollegeMofMChestMPhysicians/SocietyMofMCriticalMCareMMedicineMConsensusM
Conference,MwhichMofMtheMfollowingMareMnotMpartMofMtheMdiagnosticMcriteriaMforMsepsis?M-
MCORRECTMANSWERM-HypotensionMdefinedMasMaMsystolicMbloodMpressureMlessMthanM90MmmMHg.
(SepsisMisMdefinedMasMbacteriologicMevidenceMofMinfectionMsuperimposedMonMaMclinicalMpictureMofMSIRS.M
AccordingMtoMtheMACCP/SCCM,MbyMdefinitionMtheseMpatientsMareMhemodynamicallyMstable.MIfMtheyMshou
ldMbecomeMhemodynamicallyMunstableM(definedMasMaMsystolicMbloodMpressureM<90MmmMHg),MtheMnameM
forMtheMconditionMchangesMtoM"severeMsepsis.")
SIRSM-MCORRECTMANSWERM--MTemperatureMgreaterMthanM38°CMorMlessMthanM36°C.
, -MHeartMrateMgreaterMthanM90Mbpm.
-MRespiratoryMrateMgreaterMthanM22Mbpm
-MWhiteMbloodMcellMcountMgreaterMthanM12,000MorMlessMthanM4,000MandMgreaterMthanM10%Mbands.
abdominalMcompartmentMsyndromeM-MCORRECTMANSWERM-
OnceMdiagnosed,MtreatmentMconsistsMofMreopeningMtheMabdomenMincludingMdoingMsoMatMtheMbedsideMif
Mnecessary.
(TheMpresenceMofManMabdominalMcompartmentMsyndromeMrequiresMdecompressionMofMtheMabdomen.MIf
MtheMpatientMisMtooMunstableMtoMbeMtransportedMtoMtheMoperatingMroom,MtheMabdomenMshouldMbeMpro
mptlyMreopenedMatMtheMbedside.)
carotidMbruitM-MCORRECTMANSWERM-aMmarkerMforMgeneralizedMatherosclerosis
(InMfact,MstudiesMhaveMshownMthatMaMcarotidMbruitMisMaMriskMfactorMforMcoronaryMarteryMdiseaseMandMfut
ureMmyocardialMinfarction.)
alveolarMventilationM-MCORRECTMANSWERM-
TheMalveolarMgasMequationMcharacterizesMtheMpotentialMforMoxygenMuptakeMandMcarbonMdioxideMremoval
.
(TachypneaMatMaMgivenMminuteMventilationMincreasesManatomicMdead-
spaceMventilation,MnotMalveolarMventilation.MMinuteMventilationMisMtheMvolumeMofMgasMthatMisMinspiredMa
ndMexpiredMatMtheMnasopharynxMandMisMdifferentMthanMthatMoccurringMatMtheMalveolusMbyMtheManatomic
Mdead-
spaceMvolume.MAlthoughMarterialMPcoMisMproportionalMtoMalveolarMventilation,MarterialMPoMisMnotMasMitMm
ayMbeMaffectedMbyMphysiologicMshunting,MdiffusionMblock,MandMsoMon.MTheMRQMisMconstantMunderMnorma
lMphysiologicalMconditionsMatM±M0.8;Mhowever,MitMmayMchangeMsubstantiallyMunderMconditionsMsuchMasMa
naerobicMmetabolism,Moverfeeding,MandMsoMon.MBecauseMtheMalveolarMgasMequationMcharacterizesMtheM
partialMpressuresMofMindividualMgasesMwithinMtheMalveolus,MwhichMinMturnMdetermineMtheMindividualMgra
dientsMforMdiffusion,MtheMequationMdoesMcharacterizeMtheMpotentialMforMoxygen/carbonMdioxideMexchang
e.M)
theMfollowingMmayMconstituteMtheMphysiologicalMdeadMspaceMofMtheMrespiratoryMsystemM-
MCORRECTMANSWERM--MEmphysematousMlung.
-MLungMinvolvedMwithMaMpulmonaryMembolus.
-MProximalMtwoMthirdsMsubsegmentalMbronchi.
-MZoneMoneMalveoli.