Pathophysiology Questions & Answers
Cellular injury - ANSWERSWhat precipitates the inflammatory process?
Mast cell degranulation, activation of the coagulation cascade, activation of the kinin
cascade, release of chemotactic factors, and the activation of the complement cascade
- ANSWERSWhat are the first 5 steps of the inflammatory process?
Functions include bacterial lysis, vasodilation and increased vascular permeability,
triggers mast cell degranulation, chemotaxis, and opsonization - ANSWERSWhat is the
function of complement?
Bradykinin - ANSWERSWhat is kinin turned into?
Pain, chemotaxis, and increased vascular permeability and vasodilation -
ANSWERSWhat is bradykinin responsible for?
Kinin system - ANSWERSWhat system does the coagulation cascade have a role in
activating?
Factor XII (Hageman factor) - ANSWERSWhat factor activates kinin?
To form fibrin mesh to stop bleeding and to trap microorganisms - ANSWERSWhat is
the function of the coagulation cascade in the inflammatory process?
Activates complement and kinin system - ANSWERSWhat does the plasmin in the
coagulation cascade do?
Neutrophils, eosinophils and monocytes - ANSWERSWhat do released chemotactic
factors attract?
6-8 hours - ANSWERSHow soon do neutrophils show up at the site of injury?