Test Bank for Clayton's Basic Pharmacology for Nurses 18th Edition by Michelle J. Willihnganz, Samuel L. Gurevitz & Bruce D. Clayton ISBN 9780323550611 Chapter 1-48 | Complete Guide A+

,Chapter1:DrugDefinitions,Standards,andInformationSources Test
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Bank
b




MULTIPLECHOICE b




1. Whatisthe name under whichadrug islistedbythe U.S. Food and Drug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark

ANS: C b




The official name is the name under which a drug is listed by the FDA. The brand name, or
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trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic, name
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is provided by the U.S. Adopted Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 1 OBJ:2 b b b b b




TOP: Nursing Process Step: Assessment
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MSC: NCLEXClientNeedsCategory:Safe,EffectiveCareEnvironment
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2. Whichsource containsinformationspecificto nutritional supplements?
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a. USPDictionary of USAN & International Drug Names
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b. NaturalMedicinesComprehensive Database b b b




c. UnitedStates Pharmacopoeia/National Formulary(USPNF) b b b b b




d. DrugInteraction Facts b b




ANS: C b




United States Pharmacopoeia/National Formulary contains information specific to nutritional
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supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug names,
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pronunciation guide, and possible future FDA approved drugs; it does not include nutritional
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supplements. NaturalMedicinesComprehensiveDatabase contains evidencebased information on
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herbal medicines and herbal combination products; it does not include information specific to
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nutritional supplements. Drug Interaction Facts contains comprehensive information on drug
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interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 2 b b b b OBJ:4 b




TOP: Nursing Process Step: Assessment
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MSC: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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3. Whatisthe most comprehensivereference available to research adrug interaction?
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a. DrugFacts and Comparisons b b b




b. DrugInteraction Facts b b




c. Handbookon Injectable Drugs b b b




d. Martindale—TheCompleteDrugReference b b b




ANS: B b

, First published in 1983, Drug Interaction Facts is themost comprehensive book available on drug
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interactions. In addition to monographs listing various aspects of drug interactions, this information
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is reviewed and updated by an internationally renowned group of physicians and pharmacists with
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clinical and scientific expertise.
b b b b




DIF: Cognitive Level: Comprehension REF: p. 3 b b b b OBJ:3 b




TOP: Nursing Process Step: Assessment
b b b b b




MSC: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section of the
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Physicians’ Desk Reference (PDR) is most helpful to get information about this drug?
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a. Manufacturer‟ssection b




b. Brand and GenericName section b b b b




c. ProductCategorysection b b




d. ProductInformationsection b b




ANS: B b




Aphysician‟s orderwould include the brand and/orgenericnameofthe drug. Thealphabetic index in
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the PDR would make this section the most user friendly. Based on a physician‟s order,
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manufacturer‟s information and classification information would not be known. The
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Manufacturer‟s section is a roster of manufacturers. The Product Category section lists products
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subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics. The
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Product Information section contains reprints of the package inserts for the major products of
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manufacturers.
b




DIF: Cognitive Level: Comprehension REF: p. 3 b b b b OBJ:4 b




TOP: Nursing Process Step: Planning
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MSC: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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5. Which online drug reference makes available to health care providers and the public a standard,
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comprehensive, uptodate lookupanddownloadable resourceaboutmedicines?
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a. American Drug Index b b




b. American Hospital Formulary b b




c. DailyMed
d. Physicians’DeskReference (PDR) b b b




ANS: C b




DailyMed makes available to health careproviders and the public astandard, comprehensive, up to
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date look up and downloadable resource about medicines. The American Drug Index is not
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appropriate for patient use. The American Hospital Formulary is not appropriate for patient use.
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The PDR is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 4 b b b b OBJ:5 b




TOP: Nursing Process Step: Implementation
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MSC: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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6. Whichlegislation authorizes the FDA to determinethe safety of adrugbeforeits marketing?
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a. Federal Food, Drug, and CosmeticAct(1938) b b b b b b




b. Durham HumphreyAmendment (1952) b b b




c. ControlledSubstancesAct (1970) b b b




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, d. KefauverHarris Drug Amendment (1962) b b b b




ANS: A b




The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of all
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drugs before marketing. Later amendments and acts helped tighten FDA control and ensure drug
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safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used safely
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without medical supervision and restricts their sale to prescription by a licensedpractitioner.The
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ControlledSubstancesActaddresses onlycontrolledsubstancesand their categorization. The
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Kefauver Harris Drug Amendment ensures drug efficacy and greater drug safety. Drug
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manufacturers are required to prove to the FDA the effectiveness of their products before marketing
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them.
b




DIF: Cognitive Level: Knowledge REF: p. 4 b b b b OBJ:8 b




TOP: Nursing Process Step: Assessment
b b b b b




MSC: NCLEXClientNeedsCategory:PhysiologicalIntegrity
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7. Meperidine(Demerol) isanarcoticwith ahigh potentialforphysicalandpsychological b b b b b b b b b b b b




bdependency. Under which classification does this drug fall? b b b b b b b




a. I
b. II
c. III
d. IV
ANS: B b




Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe
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psychological and physicaldependence.Schedule Idrugshavehigh potentialforabuse and no
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recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to
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moderate physical dependence or high psychological dependence. Schedule IV drugs have low
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potential for abuse. Use may lead to limited physical or psychological dependence.
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DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ:7 b b b b b b b b




TOP: Nursing Process Step: Assessment
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MSC: NCLEXClientNeedsCategory:Safe,EffectiveCareEnvironment
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8. What would theFDAdo to expeditedrugdevelopment and approval foran outbreak of
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bsmallpox, for which there is no known treatment? b b b b b b b




a. List smallpox as ahealth orphan disease.
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b. Omitthe preclinical researchphase. b b b b




c. Extendthe clinical research phase. b b b b




d. Fasttrack theinvestigationaldrug. b b b b




ANS: D b




Once the Investigational New Drug Application has been approved, the drug can receive highest
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priority within the agency, which is called fast tracking. A smallpox outbreak would become a
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priority concern in the world. Orphan diseases are not researched in a priority manner. Preclinical
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research is not omitted. Extending any phase of the research would mean a longertimeto develop a
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vaccine.The FDA mustensurethat all phasesof the preclinical and clinical research phase have been
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completed in a safe manner.
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DIF: Cognitive Level: Knowledge b b REF: p. 7 b b OBJ:8 b




TOP: Nursing Process Step: Assessment
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