,Test Bank Pharmacotherapeutics for Advanced Practice Nurse Prescribers 6e Teri Moser Woo
xx xx xx xx xx xx xx xx xx xx xx
Woo 1
Pharmacotherapeutics for APN Prescribers, 6e xx xx xx xx Ch01
Chapter 1. The Role of the Advanced Practice Nurse as Prescriber
xx xx xx xx xx xx xx xx xx xx
MULTIPLE CHOICE xx
1. Nurse practitioner prescriptive authority is regulated by:
xx xx xx xx xx xx
A. The National Council of State Boards of Nursing
xx xx xx xx xx xx xx
B. The U.S. Drug Enforcement Administration
xx xx xx xx
C. The State Board of Nursing for each state
xx xx xx xx xx xx xx
D. The State Board of Pharmacyxx xx xx xx
ANS: x x C PTS: x x x x 1
2. The benefits to the patient of having an advanced practice registered nurse (APRN)
xx xx xx xx xx xx xx xx xx xx xx xx
prescriber include:
xx xx
A. Nurses know more about pharmacology than other prescribers because they take
xx xx xx xx xx xx xx xx xx xx
it both in their basic nursing program and in their APRN program.
xx xx xx xx xx xx xx xx xx xx xx xx
B. Nurses care for the patient from a holistic approach and include the patient
xx xx xx xx xx xx xx xx xx xx xx xx
in decision-making regarding their care.
xx xx xx xx xx
C. APRNs are less likely to prescribe narcotics and other controlled substances.
xx xx xx xx xx xx xx xx xx xx
D. APRNs are able to prescribe independently in all states, whereas a
xx xx xx xx xx xx xx xx xx xx
physician’s assistant needs to have a physician supervising their practice.
xx xx xx xx xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
3. Clinical judgment in prescribing includes:
xx xx xx xx
A. Factoring in the cost to the patient of the medication prescribed
xx xx xx xx xx xx xx xx xx xx
B. Always prescribing the newest medication available for the disease process
xx xx xx xx xx xx xx xx xx
C. Handing out drug samples to poor patients xx xx xx xx xx xx
D. Prescribing all generic medications to cut costs xx xx xx xx xx xx
ANS: x x A PTS: x x x x 1
4. The process for choosing an effective drug for a disorder includes:
xx xx xx xx xx xx xx xx xx xx
A. Asking the patient what drug they think would work best for them
xx xx xx xx xx xx xx xx xx xx xx
B. Consulting nationally recognized guidelines for disease management
xx xx xx xx xx xx
C. Prescribing medications that are available as samples before writing a prescription
xx xx xx xx xx xx xx xx xx xx
D. Following U.S. Drug Enforcement Administration guidelines for prescribing
xx xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
5. Nonintentional nonadherence of drug therapy may occur due to: xx xx xx xx xx xx xx xx
A. Belief that medication does not work
xx xx xx xx xx
B. Adverse drug reactions xx xx
C. Chronic conditions that require daily therapy
xx xx xx xx xx
D. Forgetfulness or distraction xx xx
ANS: x x D PTS: x x x x 1
, Woo 1
Pharmacotherapeutics for APN Prescribers, xx xx xx Ch02
6e
Chapter 2. Review of Basic Principles of Pharmacology
xx xx xx xx xx xx xx
MULTIPLE CHOICE xx
1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is
xx xx xx xx xx xx xx xx xx xx
critical to prescribing because:
xx xx xx xx
A. Distribution of drugs to target tissue may be affected. xx xx xx xx xx xx xx xx
B. The solubility of the drug will not match the site of absorption.
xx xx xx xx xx xx xx xx xx xx xx
C. There will be less free drug available to generate an effect.
xx xx xx xx xx xx xx xx xx xx
D. Drugs bound to albumin are readily excreted by the kidneys.
xx xx xx xx xx xx xx xx xx
ANS: x x A PTS: x x x x 1
2. Drugs that have a significant first-pass effect:
xx xx xx xx xx xx
A. Must be given by the enteral (oral) route only
xx xx xx xx xx xx xx xx
B. Bypass the hepatic circulation xx xx xx
C. Are rapidly metabolized by the liver and may have little, if any, desired action
xx xx xx xx xx xx xx xx xx xx xx xx xx
D. Are converted by the liver to more active and fat-soluble forms
xx xx xx xx xx xx xx xx xx xx
ANS: x x C PTS: x x x x 1
3. The route of excretion of a volatile drug will likely be the:
xx xx xx xx xx xx xx xx xx xx xx
A. Kidneys
B. Lungs
C. Bile and feces xx xx
D. Skin
ANS: x x B PTS: x x x x 1
4. A major disadvantage to IV administration is that:
xx xx xx xx xx xx xx
A. First-pass metabolism is eliminated. xx xx xx
B. Needles and sterility are required. xx xx xx xx
C. Absorption of the drug cannot be slowed after administration. xx xx xx xx xx xx xx xx
D. It is significantly more expensive than other routes.
xx xx xx xx xx xx xx
ANS: x x C PTS: x x x x 1
5. The nurse practitioner (NP) chooses to give cephalexin every 8 hours based on knowledge
xx xx xx xx xx xx xx xx xx xx xx xx xx
of the drug’s:
xx xx xx
A. Propensity to go to the target receptor xx xx xx xx xx xx
B. Biological half-life xx
C. Pharmacodynamics
D. Safety and side effects xx xx xx
ANS: x x B PTS: x x x x 1
6. Deferasirox is a chelating agent used to treat iron overload by binding iron to render
xx xx xx xx xx xx xx xx xx xx xx xx xx xx
it biologically inactive. This is best characterized as a(n):
xx xx xx xx xx xx xx xx xx
, Woo 2
Pharmacotherapeutics for APN Prescribers, xx xx xx Ch02
6e
A. Nonreceptor mechanism xx
B. Partial agonist xx
C. Full agonist xx
D. Noncompetitive antagonist xx
ANS: x x A PTS: x x x x 1
7. The point in time on the drug concentration curve that indicates the first sign of a
xx xx xx xx xx xx xx xx xx xx xx xx xx xx xx
therapeutic effect is the:
xx xx xx xx
A. Minimum adverse effect level xx xx xx
B. Peak of action xx xx
C. Onset of action xx xx
D. Therapeutic range xx
ANS: x x C PTS: x x x x 1
8. Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
xx xx xx xx xx xx xx xx xx xx xx xx xx
A. When the drug has a wide therapeutic range
xx xx xx xx xx xx xx
B. When the drug will be administered for a short time only
xx xx xx xx xx xx xx xx xx xx
C. When there is a high correlation between the dose and saturation of receptor sites
xx xx xx xx xx xx xx xx xx xx xx xx xx
D. To determine if a drug is in the therapeutic range
xx xx xx xx xx xx xx xx xx
ANS: x x D PTS: x x x x 1
9. A laboratory result indicates that the peak level for a drug is above the minimum
xx xx xx xx xx xx xx xx xx xx xx xx xx xx
toxic concentration. This means that the:
xx xx xx xx xx xx
A. Concentration will produce therapeutic effects. xx xx xx xx
B. Concentration will produce an adverse response. xx xx xx xx xx
C. Time between doses must be shortened.
xx xx xx xx xx
D. Duration of action of the drug is too long. xx xx xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
10. Drugs that are receptor agonists may demonstrate what property?
xx xx xx xx xx xx xx xx
A. Irreversible binding to the drug receptor site xx xx xx xx xx xx
B. Up-regulation with chronic use xx xx xx
C. Desensitization or down-regulation with continuous use xx xx xx xx xx
D. Inverse relationship between drug concentration and drug action
xx xx xx xx xx xx xx
ANS: x x C PTS: x x x x 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
xx xx xx xx xx xx xx xx xx xx
A. Down-regulation of the drug receptor xx xx xx xx
B. An exaggerated response if abruptly discontinued
xx xx xx xx xx
C. Partial blockade of the effects of agonist drugs
xx xx xx xx xx xx xx
D. An exaggerated response to competitive drug agonists
xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
xx xx xx xx xx xx xx xx xx xx xx
Woo 1
Pharmacotherapeutics for APN Prescribers, 6e xx xx xx xx Ch01
Chapter 1. The Role of the Advanced Practice Nurse as Prescriber
xx xx xx xx xx xx xx xx xx xx
MULTIPLE CHOICE xx
1. Nurse practitioner prescriptive authority is regulated by:
xx xx xx xx xx xx
A. The National Council of State Boards of Nursing
xx xx xx xx xx xx xx
B. The U.S. Drug Enforcement Administration
xx xx xx xx
C. The State Board of Nursing for each state
xx xx xx xx xx xx xx
D. The State Board of Pharmacyxx xx xx xx
ANS: x x C PTS: x x x x 1
2. The benefits to the patient of having an advanced practice registered nurse (APRN)
xx xx xx xx xx xx xx xx xx xx xx xx
prescriber include:
xx xx
A. Nurses know more about pharmacology than other prescribers because they take
xx xx xx xx xx xx xx xx xx xx
it both in their basic nursing program and in their APRN program.
xx xx xx xx xx xx xx xx xx xx xx xx
B. Nurses care for the patient from a holistic approach and include the patient
xx xx xx xx xx xx xx xx xx xx xx xx
in decision-making regarding their care.
xx xx xx xx xx
C. APRNs are less likely to prescribe narcotics and other controlled substances.
xx xx xx xx xx xx xx xx xx xx
D. APRNs are able to prescribe independently in all states, whereas a
xx xx xx xx xx xx xx xx xx xx
physician’s assistant needs to have a physician supervising their practice.
xx xx xx xx xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
3. Clinical judgment in prescribing includes:
xx xx xx xx
A. Factoring in the cost to the patient of the medication prescribed
xx xx xx xx xx xx xx xx xx xx
B. Always prescribing the newest medication available for the disease process
xx xx xx xx xx xx xx xx xx
C. Handing out drug samples to poor patients xx xx xx xx xx xx
D. Prescribing all generic medications to cut costs xx xx xx xx xx xx
ANS: x x A PTS: x x x x 1
4. The process for choosing an effective drug for a disorder includes:
xx xx xx xx xx xx xx xx xx xx
A. Asking the patient what drug they think would work best for them
xx xx xx xx xx xx xx xx xx xx xx
B. Consulting nationally recognized guidelines for disease management
xx xx xx xx xx xx
C. Prescribing medications that are available as samples before writing a prescription
xx xx xx xx xx xx xx xx xx xx
D. Following U.S. Drug Enforcement Administration guidelines for prescribing
xx xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
5. Nonintentional nonadherence of drug therapy may occur due to: xx xx xx xx xx xx xx xx
A. Belief that medication does not work
xx xx xx xx xx
B. Adverse drug reactions xx xx
C. Chronic conditions that require daily therapy
xx xx xx xx xx
D. Forgetfulness or distraction xx xx
ANS: x x D PTS: x x x x 1
, Woo 1
Pharmacotherapeutics for APN Prescribers, xx xx xx Ch02
6e
Chapter 2. Review of Basic Principles of Pharmacology
xx xx xx xx xx xx xx
MULTIPLE CHOICE xx
1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is
xx xx xx xx xx xx xx xx xx xx
critical to prescribing because:
xx xx xx xx
A. Distribution of drugs to target tissue may be affected. xx xx xx xx xx xx xx xx
B. The solubility of the drug will not match the site of absorption.
xx xx xx xx xx xx xx xx xx xx xx
C. There will be less free drug available to generate an effect.
xx xx xx xx xx xx xx xx xx xx
D. Drugs bound to albumin are readily excreted by the kidneys.
xx xx xx xx xx xx xx xx xx
ANS: x x A PTS: x x x x 1
2. Drugs that have a significant first-pass effect:
xx xx xx xx xx xx
A. Must be given by the enteral (oral) route only
xx xx xx xx xx xx xx xx
B. Bypass the hepatic circulation xx xx xx
C. Are rapidly metabolized by the liver and may have little, if any, desired action
xx xx xx xx xx xx xx xx xx xx xx xx xx
D. Are converted by the liver to more active and fat-soluble forms
xx xx xx xx xx xx xx xx xx xx
ANS: x x C PTS: x x x x 1
3. The route of excretion of a volatile drug will likely be the:
xx xx xx xx xx xx xx xx xx xx xx
A. Kidneys
B. Lungs
C. Bile and feces xx xx
D. Skin
ANS: x x B PTS: x x x x 1
4. A major disadvantage to IV administration is that:
xx xx xx xx xx xx xx
A. First-pass metabolism is eliminated. xx xx xx
B. Needles and sterility are required. xx xx xx xx
C. Absorption of the drug cannot be slowed after administration. xx xx xx xx xx xx xx xx
D. It is significantly more expensive than other routes.
xx xx xx xx xx xx xx
ANS: x x C PTS: x x x x 1
5. The nurse practitioner (NP) chooses to give cephalexin every 8 hours based on knowledge
xx xx xx xx xx xx xx xx xx xx xx xx xx
of the drug’s:
xx xx xx
A. Propensity to go to the target receptor xx xx xx xx xx xx
B. Biological half-life xx
C. Pharmacodynamics
D. Safety and side effects xx xx xx
ANS: x x B PTS: x x x x 1
6. Deferasirox is a chelating agent used to treat iron overload by binding iron to render
xx xx xx xx xx xx xx xx xx xx xx xx xx xx
it biologically inactive. This is best characterized as a(n):
xx xx xx xx xx xx xx xx xx
, Woo 2
Pharmacotherapeutics for APN Prescribers, xx xx xx Ch02
6e
A. Nonreceptor mechanism xx
B. Partial agonist xx
C. Full agonist xx
D. Noncompetitive antagonist xx
ANS: x x A PTS: x x x x 1
7. The point in time on the drug concentration curve that indicates the first sign of a
xx xx xx xx xx xx xx xx xx xx xx xx xx xx xx
therapeutic effect is the:
xx xx xx xx
A. Minimum adverse effect level xx xx xx
B. Peak of action xx xx
C. Onset of action xx xx
D. Therapeutic range xx
ANS: x x C PTS: x x x x 1
8. Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
xx xx xx xx xx xx xx xx xx xx xx xx xx
A. When the drug has a wide therapeutic range
xx xx xx xx xx xx xx
B. When the drug will be administered for a short time only
xx xx xx xx xx xx xx xx xx xx
C. When there is a high correlation between the dose and saturation of receptor sites
xx xx xx xx xx xx xx xx xx xx xx xx xx
D. To determine if a drug is in the therapeutic range
xx xx xx xx xx xx xx xx xx
ANS: x x D PTS: x x x x 1
9. A laboratory result indicates that the peak level for a drug is above the minimum
xx xx xx xx xx xx xx xx xx xx xx xx xx xx
toxic concentration. This means that the:
xx xx xx xx xx xx
A. Concentration will produce therapeutic effects. xx xx xx xx
B. Concentration will produce an adverse response. xx xx xx xx xx
C. Time between doses must be shortened.
xx xx xx xx xx
D. Duration of action of the drug is too long. xx xx xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1
10. Drugs that are receptor agonists may demonstrate what property?
xx xx xx xx xx xx xx xx
A. Irreversible binding to the drug receptor site xx xx xx xx xx xx
B. Up-regulation with chronic use xx xx xx
C. Desensitization or down-regulation with continuous use xx xx xx xx xx
D. Inverse relationship between drug concentration and drug action
xx xx xx xx xx xx xx
ANS: x x C PTS: x x x x 1
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
xx xx xx xx xx xx xx xx xx xx
A. Down-regulation of the drug receptor xx xx xx xx
B. An exaggerated response if abruptly discontinued
xx xx xx xx xx
C. Partial blockade of the effects of agonist drugs
xx xx xx xx xx xx xx
D. An exaggerated response to competitive drug agonists
xx xx xx xx xx xx
ANS: x x B PTS: x x x x 1