(OA) EXAM 2024-2025 COMPLETE UNIT
1-UNIT 7 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH
RATIONALES
Which type of genetic disease affects males more frequently than females?
Sex-linked recessive
Autosomal recessive
Autosomal dominant
Sex-linked dominant - ✔✔Sex-Linked recessive. Since males only have
one X and one Y, if the affected chromosome has the illness, it will be
expressed.
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,In which two conditions are chromosomal abnormalities the leading known
cause?
Intellectual disability
Respiratory disorders
Fetal miscarriage
Cardiovascular disease
Mental illness
Check My Answer - ✔✔Intellectual disability and fetal miscarriage.
Chromosome abnormalities are the leading known cause of intellectual
disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies?
Drug-sensitivity testing
Chorionic villus sampling (CVS)
Microscopy of cervical mucosa
Preimplantation genetic testing (PGT)
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, Amniocentesis - ✔✔Chorionic villus sampling (CVS), amniocentesis, and
preimplantation genetic testing (PGT) are examples of prenatal diagnostic
studies and are performed in vitro. CVS is a form of genetic testing that
provides genetic information found in utero and is usually performed
between weeks 11 and 14 of pregnancy. An amniocentesis is a form of
genetic testing that evaluates amniotic fluid and is usually performed during
the second trimester, between weeks 15 and 20 of pregnancy. PGT is
performed on the embryo prior to implantation.
Which genetic disorder is characterized by the presence of a zygote having
one chromosome with a normal complement of genes and one
chromosome with a missing gene?
Klinefelter syndrome
Down syndrome
Cri du chat syndrome
Turner syndrome - ✔✔Cri du chat syndrome (translated as "cry of the cat")
is caused by a DNA deletion. This term describes the cry often heard from
a baby affected by the syndrome. Cri du chat syndrome can present as a
microcephalic, low birth-weight baby with a piercing cry.
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