PHARMACOLOGY, 2024/2025 WITH
CORRECT/ACCURATE ANSWERS
The five characteristics of inflammation - CORRECT ANSWERS-
"the cardinal signs of inflammation"
1-redness
2-swelling (edema)
3-heat
4-pain
5-loss of function.
Inflammation - CORRECT ANSWERS- a response to tissue injury
and infection. When the inflammatory process occurs, a vascular
reaction takes place in which fluid, elements of blood, leukocytes
(white blood cells [WBCs]), and chemical mediators accumulate at
the injured tissue or infection site. The process of inflammation is
a protective mechanism in which the body attempts to neutralize
and destroy harmful agents at the site of injury and to establish
conditions for tissue repair
Infection - CORRECT ANSWERS- caused by microorganisms and
results in inflammation, *but not all inflammations are caused by
infections
, NSAIDs - CORRECT ANSWERS- are aspirin and aspirin-like drugs
that inhibit the enzyme COX, which is needed for the biosynthesis
of prostaglandins.
salycilates - CORRECT ANSWERS- Aspirin comes from the family
of salicylates derived from salicylic acid. Aspirin is also called
acetylsalicylic acid (ASA) after the acetyl group used in the
composition of aspirin
COX1 and COX2 - CORRECT ANSWERS- two enzyme forms of
cyclooxygenase, symbolized as COX-1 and COX-2. COX-1 protects
the stomach lining and regulates blood platelets, promoting blood
clotting. COX-2 triggers pain and inflammation at the injured site.
NSAID herbal alert - CORRECT ANSWERS- Dong quai, feverfew,
garlic, ginger, and ginkgo may cause bleeding when taken with
nonsteroidal antiinflammatory drugs (NSAIDs)
Immunosuppressives - CORRECT ANSWERS- are used to treat
refractory rheumatoid arthritis (arthritis that does not respond to
antiinflammatory drugs). In low doses, selected
immunosuppressive agents have been effective in the treatment
of rheumatoid arthritis
Immunomodulators - CORRECT ANSWERS- treat moderate to
severe rheumatoid arthritis by disrupting the inflammatory
process and delaying disease progression. Interleukin (IL-1)