Understanding
Pathophysiology g
6th Edition Hueth
g g
er Test Bank.
g g
, UnderstandinggPathophysiologyg6thgEditiongHuethergTestgBank
Chapter 01: Cellular Biology
g g g
Huether & McCance: Understanding Pathophysiology, 6th Edition
g g g g g g
MULTIPLEgCHOICE
1. Agstudentgisgobservinggagcellgundergthegmicroscope.gItgisgobservedgtoghavegsupercoiledgDNAg
withghistones.gWhichgofgthegfollowinggwouldgalsogbegobservedgbygthegstudent?
a. Agsinglegcirculargchromosome
b. Agnucleus
c. Free-floatinggnucleargmaterial
d. Nogorganelles
ANS:g B
Thegcellgdescribedgisgageukaryoticgcell,gsogitghasghistonesgandgagsupercoiledgDNAgwithingitsgn
ucleus;gthus,gthegnucleusgshouldgbegobserved.gAgsinglegcirculargchromosomegcalledgagprokar
yotegcontainsgfree-floatinggnucleargmaterialgbutghasgnogorganelles.
REF:g p.g2
2. Agnursegisginstructinggthegstaffgaboutgcellulargfunctions.gWhichgcellulargfunctiongisgthegnursegde
scribinggwhengangisolatedgcellgabsorbsgoxygengandgusesgitgtogtransformgnutrientsgtogenergy?
a. Metabolicgabsorption
b. Communication
c. Secretion
d. Respiration
ANS:g D NURSINGTB.COM
Thegcell’sgabilitygtogabsorbgoxygengisgreferredgtogasgrespirationgwhilegitsgcommunicationgabilitygi
nvolvesgmaintenancegofgagsteadygdynamicgstate,gmetabolicgabsorptiongprovidesgnutrition,gandgse
cretiongallowsgforgthegsynthesizinggofgnewgsubstances.
REF:g p.g2
3. AgeukaryoticgcellgisgundergoinggDNAgreplication.gIngwhichgregiongofgthegcellgwouldgmostgofgt
heggeneticginformationgbegcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusgCytoplasm
ANS:g C
Thegregiongofgthegcellgthatgcontainsggeneticgmaterial,gincludinggaglargegamountgofgribonucleicga
cid,gmostgofgthegDNA,gandgDNA-
bindinggproteins,gisgthegnucleolus,gwhichgisglocatedgwithingthegcell’sgnucleus.gMitochondriagisg
associatedgwithgcellulargrespiration,gwhilegribosomesgareginvolvedgwithgproteingmanufacturin
g.gCytoplasmgisgagfluidgfillinggthatgisgagcomponentgofgthegcell.
REF:g p.g2
NURSINGTB.COM
, UnderstandinggPathophysiologyg6thgEditiongHuethergTestgBank
4. Whichgofgthegfollowinggcangremovegproteinsgattachedgtogthegcell’sgbilayergbygdissolvinggthegl
ayergitself?
a. Peripheralgmembranegproteins
b. Integralgmembranegproteins
c. Glycoproteins
d. Cellgadhesiongmolecules
ANS:g B
Proteinsgdirectlygattachedgtogthegmembranegbilayergcangbegremovedgbygthegactiongofgintegralg
membranegproteinsgthatgdissolvegthegbilayer.gPeripheralgmembranegproteinsgresidegatgthegsurf
acegwhilegcellgadhesiongmoleculesgaregongthegoutsidegofgthegmembrane.gGlycoproteingmarksgc
ellsgandgdoesgnotgfloat.
REF:g p.g7
5. Whichgofgthegfollowinggcangbindgtogplasmagmembranegreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicglipids
d. Ligands
ANS:g D
Ligandsgaregthegonlygspecificgmoleculesgthatgcangbindgwithgreceptorsgongthegcellgmembrane.
REF:g p.g9
6. Agnursegisgreviewinggagreportgfromgagpatientgwithgmetastaticgcancer.gWhatgalternationgingthege
xtracellulargmatrixgwouldgsuN
ppoR
rtgthIegdG
iagnBo.
siC
sgofM
metastaticgcancer?
a. Decreasedgfibronectin
U gSgNgT O
b. Increasedgcollagen
c. Decreasedgelastin
d. Increasedgglycoproteins
ANS:g A
Onlygagreducedgamountgofgfibronectingisgfoundgingsomegtypesgofgcancerousgcells,gallowinggt
hemgtogtravelgorgmetastasize.
REF:g p.g10
7. Whichgformgofgcellgcommunicationgisgusedgtogrelategtogothergcellsgingdirectgphysicalgcontact?
a. Cellgjunction
b. Gapgjunction
c. Desmosome
d. Tightgjunction
ANS:g A
Cellgjunctionsgholdgcellsgtogethergandgpermitgmoleculesgtogpassgfromgcellgtogcell.
Gapgjunctionsgallowgforgcellulargcommunicationgbetweengcells.gNeithergdesmosomesgnorgtightgj
unctionsgaregassociatedgwithgcellulargcommunication.
REF:g p.g11
NURSINGTB.COM
, UnderstandinggPathophysiologyg6thgEditiongHuethergTestgBank
8. Pancreaticgbetagcellsgsecreteginsulin,gwhichginhibitsgsecretiongofgglucagongfromgneighboringga
lphagcells.gThisgactiongisgangexamplegofgwhichgofgthegfollowinggsignalinggtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:g A
Paracrinegsignalingginvolvesgthegreleasegofglocalgchemicalgmediatorsgthatgaregquicklygtakengup,gd
estroyed,gorgimmobilized,gasgingthegcasegofginsulingandgtheginhibitiongofgthegsecretiongofgglucago
n.gNonegofgthegothergoptionsginvolvegsignalinggthatgisgassociatedgwithgaglocalgchemicalgmediatorg
likeginsulin.
REF:g p.g12
9. Ingcellulargmetabolism,geachgenzymeghasgaghighgaffinitygforga:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:g B
Eachgenzymeghasgaghighgaffinitygforgagsubstrate,gagspecificgsubstancegconvertedgtogagproductgofgt
hegreaction.gCellulargmetabolismgisgnotgdependentgongangattractiongbetweengangenzymegandganyg
ofgthegremaininggoptions.
REF:gggp.g16
NURSINGTB.COM
10. Angathletegrunsgagmarathon,gaftergwhichghisgmusclesgfeelgfatiguedgandgunablegtogcontract.gThegat
hletegasksgthegnursegwhygthisghappened.gThegnurse’sgresponsegisgbasedgongthegknowledgegthatgtheg
problemgisgresultgofgagdeficiencygof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:g C
WhengATPgisgdeficient,gimpairedgmusclegcontractiongresults.gNonegofgthegothergoptionsgaregi
nvolvedgingmusclegcontraction.
REF:g p.g16
11. WhichgphasegofgcatabolismgproducesgthegmostgATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricgacidgcycle
ANS:g D
WhilegsomegATPgisgproducedgduringgthegoxidationgandgglycolysisgphases,gmostgofgthegATPgisgg
eneratedgduringgthegcitricgacidgcycle.gDigestiongdoesgnotgproduceganygATP.
NURSINGTB.COM
Pathophysiology g
6th Edition Hueth
g g
er Test Bank.
g g
, UnderstandinggPathophysiologyg6thgEditiongHuethergTestgBank
Chapter 01: Cellular Biology
g g g
Huether & McCance: Understanding Pathophysiology, 6th Edition
g g g g g g
MULTIPLEgCHOICE
1. Agstudentgisgobservinggagcellgundergthegmicroscope.gItgisgobservedgtoghavegsupercoiledgDNAg
withghistones.gWhichgofgthegfollowinggwouldgalsogbegobservedgbygthegstudent?
a. Agsinglegcirculargchromosome
b. Agnucleus
c. Free-floatinggnucleargmaterial
d. Nogorganelles
ANS:g B
Thegcellgdescribedgisgageukaryoticgcell,gsogitghasghistonesgandgagsupercoiledgDNAgwithingitsgn
ucleus;gthus,gthegnucleusgshouldgbegobserved.gAgsinglegcirculargchromosomegcalledgagprokar
yotegcontainsgfree-floatinggnucleargmaterialgbutghasgnogorganelles.
REF:g p.g2
2. Agnursegisginstructinggthegstaffgaboutgcellulargfunctions.gWhichgcellulargfunctiongisgthegnursegde
scribinggwhengangisolatedgcellgabsorbsgoxygengandgusesgitgtogtransformgnutrientsgtogenergy?
a. Metabolicgabsorption
b. Communication
c. Secretion
d. Respiration
ANS:g D NURSINGTB.COM
Thegcell’sgabilitygtogabsorbgoxygengisgreferredgtogasgrespirationgwhilegitsgcommunicationgabilitygi
nvolvesgmaintenancegofgagsteadygdynamicgstate,gmetabolicgabsorptiongprovidesgnutrition,gandgse
cretiongallowsgforgthegsynthesizinggofgnewgsubstances.
REF:g p.g2
3. AgeukaryoticgcellgisgundergoinggDNAgreplication.gIngwhichgregiongofgthegcellgwouldgmostgofgt
heggeneticginformationgbegcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusgCytoplasm
ANS:g C
Thegregiongofgthegcellgthatgcontainsggeneticgmaterial,gincludinggaglargegamountgofgribonucleicga
cid,gmostgofgthegDNA,gandgDNA-
bindinggproteins,gisgthegnucleolus,gwhichgisglocatedgwithingthegcell’sgnucleus.gMitochondriagisg
associatedgwithgcellulargrespiration,gwhilegribosomesgareginvolvedgwithgproteingmanufacturin
g.gCytoplasmgisgagfluidgfillinggthatgisgagcomponentgofgthegcell.
REF:g p.g2
NURSINGTB.COM
, UnderstandinggPathophysiologyg6thgEditiongHuethergTestgBank
4. Whichgofgthegfollowinggcangremovegproteinsgattachedgtogthegcell’sgbilayergbygdissolvinggthegl
ayergitself?
a. Peripheralgmembranegproteins
b. Integralgmembranegproteins
c. Glycoproteins
d. Cellgadhesiongmolecules
ANS:g B
Proteinsgdirectlygattachedgtogthegmembranegbilayergcangbegremovedgbygthegactiongofgintegralg
membranegproteinsgthatgdissolvegthegbilayer.gPeripheralgmembranegproteinsgresidegatgthegsurf
acegwhilegcellgadhesiongmoleculesgaregongthegoutsidegofgthegmembrane.gGlycoproteingmarksgc
ellsgandgdoesgnotgfloat.
REF:g p.g7
5. Whichgofgthegfollowinggcangbindgtogplasmagmembranegreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicglipids
d. Ligands
ANS:g D
Ligandsgaregthegonlygspecificgmoleculesgthatgcangbindgwithgreceptorsgongthegcellgmembrane.
REF:g p.g9
6. Agnursegisgreviewinggagreportgfromgagpatientgwithgmetastaticgcancer.gWhatgalternationgingthege
xtracellulargmatrixgwouldgsuN
ppoR
rtgthIegdG
iagnBo.
siC
sgofM
metastaticgcancer?
a. Decreasedgfibronectin
U gSgNgT O
b. Increasedgcollagen
c. Decreasedgelastin
d. Increasedgglycoproteins
ANS:g A
Onlygagreducedgamountgofgfibronectingisgfoundgingsomegtypesgofgcancerousgcells,gallowinggt
hemgtogtravelgorgmetastasize.
REF:g p.g10
7. Whichgformgofgcellgcommunicationgisgusedgtogrelategtogothergcellsgingdirectgphysicalgcontact?
a. Cellgjunction
b. Gapgjunction
c. Desmosome
d. Tightgjunction
ANS:g A
Cellgjunctionsgholdgcellsgtogethergandgpermitgmoleculesgtogpassgfromgcellgtogcell.
Gapgjunctionsgallowgforgcellulargcommunicationgbetweengcells.gNeithergdesmosomesgnorgtightgj
unctionsgaregassociatedgwithgcellulargcommunication.
REF:g p.g11
NURSINGTB.COM
, UnderstandinggPathophysiologyg6thgEditiongHuethergTestgBank
8. Pancreaticgbetagcellsgsecreteginsulin,gwhichginhibitsgsecretiongofgglucagongfromgneighboringga
lphagcells.gThisgactiongisgangexamplegofgwhichgofgthegfollowinggsignalinggtypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS:g A
Paracrinegsignalingginvolvesgthegreleasegofglocalgchemicalgmediatorsgthatgaregquicklygtakengup,gd
estroyed,gorgimmobilized,gasgingthegcasegofginsulingandgtheginhibitiongofgthegsecretiongofgglucago
n.gNonegofgthegothergoptionsginvolvegsignalinggthatgisgassociatedgwithgaglocalgchemicalgmediatorg
likeginsulin.
REF:g p.g12
9. Ingcellulargmetabolism,geachgenzymeghasgaghighgaffinitygforga:
a. solute.
b. substrate.
c. receptor.
d. ribosome.
ANS:g B
Eachgenzymeghasgaghighgaffinitygforgagsubstrate,gagspecificgsubstancegconvertedgtogagproductgofgt
hegreaction.gCellulargmetabolismgisgnotgdependentgongangattractiongbetweengangenzymegandganyg
ofgthegremaininggoptions.
REF:gggp.g16
NURSINGTB.COM
10. Angathletegrunsgagmarathon,gaftergwhichghisgmusclesgfeelgfatiguedgandgunablegtogcontract.gThegat
hletegasksgthegnursegwhygthisghappened.gThegnurse’sgresponsegisgbasedgongthegknowledgegthatgtheg
problemgisgresultgofgagdeficiencygof:
a. GTP
b. AMP
c. ATP
d. GMP
ANS:g C
WhengATPgisgdeficient,gimpairedgmusclegcontractiongresults.gNonegofgthegothergoptionsgaregi
nvolvedgingmusclegcontraction.
REF:g p.g16
11. WhichgphasegofgcatabolismgproducesgthegmostgATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citricgacidgcycle
ANS:g D
WhilegsomegATPgisgproducedgduringgthegoxidationgandgglycolysisgphases,gmostgofgthegATPgisgg
eneratedgduringgthegcitricgacidgcycle.gDigestiongdoesgnotgproduceganygATP.
NURSINGTB.COM
