,NUR301 EXAM QUESTIONS AND
ANSWERS 100% CORRECT!
What is an NSAID used for? - ANSWER mild to moderate pain
What are the NSAIDs we must know? - ANSWER diclofenac
aspirin
naproxen
ibuprofen
celecoxib
What is the different in mechanism of action between 1st generation and 2nd generation
NSAIDs? - ANSWER 1st generation: inhibits both COX-1 and COX-2
2nd generation: inhibits COX-2 only
General mechanism of action (MOA) for NSAIDs - ANSWER - inhibits COX-1 and COX-
2, which inhibits prostaglandin synthesis centrally and peripherally
- antipyretic
- anti-inflammatory
- antihistamine
General side effects of NSAIDs - ANSWER - GI upset/bleeding
- Renal Toxicity
- Liver Effects (jaundice or hepatitis)
- Hypertension/CVA/MI
- Setven's Johnson Syndrome
- Seizures
- Headache
- Nervousness
General nursing considerations for NSAIDs - ANSWER - take with food (specifically
protein rich in order to coat)
- caution with cardiac patients or patients with high BP
- caution for patients with bleeding risk (ex: if taking warfarin)
- monitor pain level
- do not crush, may give liquid
Additional MOA for aspirin - ANSWER - Decrease platelet aggregation
, Additional side effects (SE) for aspirin - ANSWER A - abdominal pain & asthma trigger
S - salicylism
P - Peptic ulcer disease
I - Intestinal bleeding
R - Reye's Syndrome & respiratory distress (Laryngeal edema)
I - Itchy/rash
N - noise (tinnitus)
Additional nursing consideration for diclofenac - ANSWER - Monitor skin integrity
Specific use for diclofenac - ANSWER Knee and back pain
What is the 2nd generation NSAID we must know? - ANSWER celecoxib (Celebrex)
What is celecoxib's MOA? - ANSWER inhibits COX-2
Additional SE for celecoxib - ANSWER - lower GI risk (better for long-term use)
- greater risk for MI
What is an example of a non-opioid analgesic? - ANSWER acetaminophen (Tylenol)
What is the mechanism of action for acetaminophen? - ANSWER Inhibits prostaglandin
synthesis in the CNS (centrally)
What are the side effects (SE) of acetaminophen? - ANSWER - Hepatotoxicity
- Hypotension
- Fever/sweating
- Headache
- N&V
- Steven's Johnson Syndrome
- Jaundice
What are the nursing considerations for acetaminophen? - ANSWER - Be cautious
when combining with other acetaminophen containing medications (ex: opioids)
- Avoid: ETOH (alcohol)
What is the antidote for acetaminophen? - ANSWER acetylcysteine (Mucomyst)
What routes can acetaminophen be given? - ANSWER PO & rectal
ANSWERS 100% CORRECT!
What is an NSAID used for? - ANSWER mild to moderate pain
What are the NSAIDs we must know? - ANSWER diclofenac
aspirin
naproxen
ibuprofen
celecoxib
What is the different in mechanism of action between 1st generation and 2nd generation
NSAIDs? - ANSWER 1st generation: inhibits both COX-1 and COX-2
2nd generation: inhibits COX-2 only
General mechanism of action (MOA) for NSAIDs - ANSWER - inhibits COX-1 and COX-
2, which inhibits prostaglandin synthesis centrally and peripherally
- antipyretic
- anti-inflammatory
- antihistamine
General side effects of NSAIDs - ANSWER - GI upset/bleeding
- Renal Toxicity
- Liver Effects (jaundice or hepatitis)
- Hypertension/CVA/MI
- Setven's Johnson Syndrome
- Seizures
- Headache
- Nervousness
General nursing considerations for NSAIDs - ANSWER - take with food (specifically
protein rich in order to coat)
- caution with cardiac patients or patients with high BP
- caution for patients with bleeding risk (ex: if taking warfarin)
- monitor pain level
- do not crush, may give liquid
Additional MOA for aspirin - ANSWER - Decrease platelet aggregation
, Additional side effects (SE) for aspirin - ANSWER A - abdominal pain & asthma trigger
S - salicylism
P - Peptic ulcer disease
I - Intestinal bleeding
R - Reye's Syndrome & respiratory distress (Laryngeal edema)
I - Itchy/rash
N - noise (tinnitus)
Additional nursing consideration for diclofenac - ANSWER - Monitor skin integrity
Specific use for diclofenac - ANSWER Knee and back pain
What is the 2nd generation NSAID we must know? - ANSWER celecoxib (Celebrex)
What is celecoxib's MOA? - ANSWER inhibits COX-2
Additional SE for celecoxib - ANSWER - lower GI risk (better for long-term use)
- greater risk for MI
What is an example of a non-opioid analgesic? - ANSWER acetaminophen (Tylenol)
What is the mechanism of action for acetaminophen? - ANSWER Inhibits prostaglandin
synthesis in the CNS (centrally)
What are the side effects (SE) of acetaminophen? - ANSWER - Hepatotoxicity
- Hypotension
- Fever/sweating
- Headache
- N&V
- Steven's Johnson Syndrome
- Jaundice
What are the nursing considerations for acetaminophen? - ANSWER - Be cautious
when combining with other acetaminophen containing medications (ex: opioids)
- Avoid: ETOH (alcohol)
What is the antidote for acetaminophen? - ANSWER acetylcysteine (Mucomyst)
What routes can acetaminophen be given? - ANSWER PO & rectal
