©THEBRIGHT EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
NURS 5461 EXAM 1 Questions With
Verified Answers
Microcytic Anemia - Answers✔Iron deficiency, usually due to malabsorption/occult blood loss,
or lead poisoning. MCV <80
Normocytic Anemia - Answers✔Due to hemorrhage or chronic disease. Aplastic anemia. MCV
80-92
Macrocytic Anemia - Answers✔Due to folate or vitamin B12 (cobalamin) deficiency
(megaloblastic anemia)/pernicious anemia/liver diseases
Serum Ferritin - Answers✔Tests for iron stores. As serum ferritin falls, TIBC rises, and serum
iron levels will eventually fall.
Anemia of Chronic Disease - Answers✔Normocytic anemia with ↓ serum iron, ↓ TIBC, and
normal iron stores. Treat with epoetin and give an iron supplement
Schistocytes - Answers✔Associated with hemolytic uremia syndrome
Pernicious Anemia - Answers✔Macrocytic anemia caused by vitamin B12 deficiency. B12 is
essential to maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and
histamine2 blockers can cause this.
Increased Homocysteine & Methylmalonic Acid Level - Answers✔Indicates B12 deficiency
Increased Homocysteine Levels - Answers✔Folate deficiency
Spherocytes - Answers✔Appear as spheres, lack central pallor, smaller diameter, indicate
immune-mediated process - can be seen after blood transfusion
Aplastic Anemia - Answers✔Failure of bone marrow to produce red blood cells
Low Ferritin - Answers✔Iron Deficiency Anemia
Transferrin - Answers✔Transports Iron
, ©THEBRIGHT EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
TIBC (Total Iron Binding Capacity) - Answers✔Available transferrin that is left unbound.
Reflects iron levels.
MCHC (Mean Corpuscular Hemoglobin Concentration) - Answers✔Concentration of
hemoglobin per RBC
Alzheimer's Disease - Answers✔Gradual onset with early memory impairment. Most common
form of dementia.
Lewy Body Dementia - Answers✔Rapidly progressive dementia seen with Parkinson syndrome.
Visual hallucinations present.
Frontal Lobe Dementia - Answers✔Personality impairments before age 60. PDG-PET Scan
testing.
PDG-PET Scan - Answers✔Measures brain glucose metabolism. Decreased uptake in
Alzheimer's.
SSRIs - Answers✔Fluoxetine, Paroxetine, Sertraline, Citalopram
Cholinesterase Inhibitors - Answers✔Donepezil, Rivastigmine, Galantamine
Delirium - Answers✔Acute onset confusion caused by cholinergic deficiency / Anticholinergic
overdose. HALDO treatment of choice unless patient has Parkinson's or dementia with Lewy
bodies - use Quetiapine
Mania in Dementia - Answers✔Divalproex (Depakote)
First Recommended Treatment for Depression - Answers✔Exercise
Bipolar Depression Treatment - Answers✔Mood stabilizer - Lamotrigine first
Fluoxetine (Prozac) - Answers✔SSRI - Avoid in older adults - long half-life and too energizing
Neurotransmitter Lost in Alzheimer's - Answers✔Acetylcholine
Diagnosis for Lewy Body / Parkinson Dementia - Answers✔Must include visual hallucinations
and/or Parkinson's signs
Memantine - Answers✔Used for severe Alzheimer's and in combination with a cholinesterase
inhibitor
Citalopram (Celexa) - Answers✔SSRI. Effective in treating agitation and psychosis - no more
than 20mg due to prolonged QT
Treatment for Mania in Dementia - Answers✔Divalproex Sodium (Depakote) - Monitor liver
function
ALL RIGHTS RESERVED.
NURS 5461 EXAM 1 Questions With
Verified Answers
Microcytic Anemia - Answers✔Iron deficiency, usually due to malabsorption/occult blood loss,
or lead poisoning. MCV <80
Normocytic Anemia - Answers✔Due to hemorrhage or chronic disease. Aplastic anemia. MCV
80-92
Macrocytic Anemia - Answers✔Due to folate or vitamin B12 (cobalamin) deficiency
(megaloblastic anemia)/pernicious anemia/liver diseases
Serum Ferritin - Answers✔Tests for iron stores. As serum ferritin falls, TIBC rises, and serum
iron levels will eventually fall.
Anemia of Chronic Disease - Answers✔Normocytic anemia with ↓ serum iron, ↓ TIBC, and
normal iron stores. Treat with epoetin and give an iron supplement
Schistocytes - Answers✔Associated with hemolytic uremia syndrome
Pernicious Anemia - Answers✔Macrocytic anemia caused by vitamin B12 deficiency. B12 is
essential to maturation of erythrocytes - low levels will cause the RBC to expand. PPIs and
histamine2 blockers can cause this.
Increased Homocysteine & Methylmalonic Acid Level - Answers✔Indicates B12 deficiency
Increased Homocysteine Levels - Answers✔Folate deficiency
Spherocytes - Answers✔Appear as spheres, lack central pallor, smaller diameter, indicate
immune-mediated process - can be seen after blood transfusion
Aplastic Anemia - Answers✔Failure of bone marrow to produce red blood cells
Low Ferritin - Answers✔Iron Deficiency Anemia
Transferrin - Answers✔Transports Iron
, ©THEBRIGHT EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
TIBC (Total Iron Binding Capacity) - Answers✔Available transferrin that is left unbound.
Reflects iron levels.
MCHC (Mean Corpuscular Hemoglobin Concentration) - Answers✔Concentration of
hemoglobin per RBC
Alzheimer's Disease - Answers✔Gradual onset with early memory impairment. Most common
form of dementia.
Lewy Body Dementia - Answers✔Rapidly progressive dementia seen with Parkinson syndrome.
Visual hallucinations present.
Frontal Lobe Dementia - Answers✔Personality impairments before age 60. PDG-PET Scan
testing.
PDG-PET Scan - Answers✔Measures brain glucose metabolism. Decreased uptake in
Alzheimer's.
SSRIs - Answers✔Fluoxetine, Paroxetine, Sertraline, Citalopram
Cholinesterase Inhibitors - Answers✔Donepezil, Rivastigmine, Galantamine
Delirium - Answers✔Acute onset confusion caused by cholinergic deficiency / Anticholinergic
overdose. HALDO treatment of choice unless patient has Parkinson's or dementia with Lewy
bodies - use Quetiapine
Mania in Dementia - Answers✔Divalproex (Depakote)
First Recommended Treatment for Depression - Answers✔Exercise
Bipolar Depression Treatment - Answers✔Mood stabilizer - Lamotrigine first
Fluoxetine (Prozac) - Answers✔SSRI - Avoid in older adults - long half-life and too energizing
Neurotransmitter Lost in Alzheimer's - Answers✔Acetylcholine
Diagnosis for Lewy Body / Parkinson Dementia - Answers✔Must include visual hallucinations
and/or Parkinson's signs
Memantine - Answers✔Used for severe Alzheimer's and in combination with a cholinesterase
inhibitor
Citalopram (Celexa) - Answers✔SSRI. Effective in treating agitation and psychosis - no more
than 20mg due to prolonged QT
Treatment for Mania in Dementia - Answers✔Divalproex Sodium (Depakote) - Monitor liver
function
