S S S S S
CLINICOPATHOLOGIC FOUNDATIONS S S
OF MEDICINE 7TH EDITION 2023 HIGH G
S S S S S S
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S S S S
1. IschemiaSandSotherStoxicSinjuriesSincreaseStheSaccumulationSofSintracellularScalciumSasSaSresultS
of:
A) releaseSofSstoredScalciumSfromStheSmitochondria.
B) improvedSintracellularSvolumeSregulation.
C) decreasedSinfluxSacrossStheScellSmembrane.
D) attractionSofScalciumStoSfattySinfiltrates.
2. TheSpatientSisSfoundStoShaveSliverSdisease,SresultingSinStheSremovalSofSaSlobeSofShisSliver.SAdapta
tionStoStheSreducedSsizeSofStheSliverSleadsStoS_ ofStheSremainingSliverScells.
A) metaplasia
B) organSatrophy
C) compensatoryShyperplasia
D) physiologicShypertrophy
ASpersonSeatingSpeanutsSstartsSchokingSandScollapses.SHisSairwaySobstructionSisSpartiallySc
leared,SbutSheSremainsShypoxicSuntilSheSreachesStheShospital.STheSprolongedScellShypoxiaSc
3. ausedSaScerebralSinfarctionSandSresulting _SinStheSbrain.
A) caspaseSactivation
B) coagulationSnecrosis
C) rapidSphagocytosis
D) proteinSp53Sdeficiency
4. BacteriaS andS virusesS causeS cellS damageS byS ,S whichS isS uniqueS fromS theS intracellularS damageSca
edSbySotherSinjuriousSagents.
, A) disruptingStheSsodium/potassiumSATPaseSpump
B) interruptingSoxidativeSmetabolismSprocesses
ChapterS1:SCellSAdaptation,SInjurySandSDeath
C) replicatingSandSproducingScontinuedSinjury
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S S S S S
INICOPATHOLOGIC FOUNDATIONS OF S S
MEDICINE 7TH EDITION ( WITH ANSWER
S S S S S S S
KEY)
5. TheSpatientShasSaSprolongedSinterruptionSinSarterialSbloodSflowStoShisSleftSkidney,ScausingS
hypoxicScellSinjurySandStheSreleaseSofSfreeSradicals.SFreeSradicalsSdamageScellsSby:
A) destroyingSphospholipidsSinStheScellSmembrane.
B) alteringStheSimmuneSresponseSofStheScell.
C) disruptingScalciumSstorageSinStheScell.
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D) decreasingSproteinSsynthesisSandSfunction
D) inactivationSofSenzymesSandSmitochondria.
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S S S
GUIDE 2023 S
,TEST BANK FOR RUBIN’S PATHOLOGY:
S S S S
CLINICOPATHOLOGIC FOUNDATIONS S
OF
MEDICINE 7TH EDITION ( WITH ANSWER
S S S S S S
KEY)
6. InjuredScellsShaveSimpairedSflowSofSsubstancesSthroughStheScellSmembraneSasSaSresultSof:
A) increasedSfatSload.
B) alteredSpermeability.
C) alteredSglucoseSutilization.
D) increasedSsurfaceSreceptors.
7. ReversibleSadaptiveSintracellularSresponsesSareSinitiatedSby:
A) stimulusSoverload.
B) geneticSmutations.
C) chemicalSmessengers.
D) mitochondrialSDNA.
8. InjuredScellsSbecomeSverySswollenSasSaSresultSof:
A) increasedScellSproteinSsynthesis.
B) alteredScellSvolumeSregulation.
C) passiveSentrySofSpotassiumSintoStheScell.
D) blebSformationSinStheSplasmaSmembrane.
ASdiabeticSpatientShasSimpairedSsensation,Scirculation,SandSoxygenationSofShisSfeet.SHeSstepsSonS
aSpieceSofSglass,StheSwoundSdoesSnotSheal,SandStheSareaStissueSbecomesSnecrotic.STheSnecroticSc
9. ellSdeathSisScharacterizedSby:
A) rapidSapoptosis.
B) cellularSrupture.
C) shrinkageSandScollapse.
D) chronicSinflammation.
10. AS99-year-
oldSwomanShasSexperiencedStheSdeclineSofScellSfunctionSassociatedSwithSage.SASgroupSofSth
eoriesSofScellularSagingSfocusSonSprogrammed:
, A) changesSwithSgeneticSinfluences.
B) eliminationSofScellSreceptorSsites.
C) insufficientStelomeraseSenzyme.
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