NR 507||NR 507 BEST EXAM
QUESTION WITH VERIFIED
ANSWERS IN Advanced
Pathophysiology WELL DEFINED
(verified 2024/2025) GRADED A+
Asthma (CORRECT ANSWER) Chronic disease due to
bronchoconstriction and an excessive inflammatory response in the
bronchioles
What are 5 s/s of asthma (CORRECT ANSWER) coughing
wheezing
shortness of breath
rapid breathing
chest tightness
Pathophysiology of asthma (5) (CORRECT ANSWER) -airway
inflammation, bronchial hyper-reactivity and smooth muscle spasm
-excess mucus production and accumulation
-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
,Bronchioles (CORRECT ANSWER) smaller passageways that originate
from the bronchi that become the alveoli
3 layers of the bronchioles (CORRECT ANSWER) innermost layer
middle layer - lamina propria
outermost layer
lamina propria (CORRECT ANSWER) the middle layer of the
bronchioles
structure of the lamina propria (CORRECT ANSWER) embedded with
connective tissue cells and immune cells
purpose of the lamina propria (CORRECT ANSWER) white blood cells
are present to help protect the airways
How does the lamina propria effect the lungs in regards to asthma
(CORRECT ANSWER) the WBCs protective feature goes into
overdrive causing an inflammatory response that damages host tissue
What does the innermost layer of the bronchioles contain (CORRECT
ANSWER) columnar epithelial ells and mucus producing goblet cells
What does the outermost layer of the bronchioles contain (CORRECT
ANSWER) smooth muscle cells
, what does the outermost layer of the bronchioles do (CORRECT
ANSWER) control the airways ability to constrict and dilate
alveolar hyperinflation (CORRECT ANSWER) When air is unable to
move out of the alveolar like it should due to bronchial walls collapsing
around possible mucus plug thus trapping air inside
how does hyperinflation occur? (CORRECT ANSWER) the ongoing
inflammatory process of asthma produces mucus and pus plug that the
bronchial walls collapse around
Effect of hyperinflation of the alveolar (CORRECT ANSWER) -
expanded thorax and hypercapnia (retention of CO2)
- respiratory acidosis
What are two anticholinergic drugs used for asthma (CORRECT
ANSWER) tiotropium and ipratropium
What do anticholinergics do in the lungs? (CORRECT ANSWER)
These drugs block the effects of the parasympathetic nervous system
- increasing bronchodilation
MOA of anticholinergic drugs for asthma (CORRECT ANSWER) the
parasympathetic system is stimulated by the vagal nerve to release
QUESTION WITH VERIFIED
ANSWERS IN Advanced
Pathophysiology WELL DEFINED
(verified 2024/2025) GRADED A+
Asthma (CORRECT ANSWER) Chronic disease due to
bronchoconstriction and an excessive inflammatory response in the
bronchioles
What are 5 s/s of asthma (CORRECT ANSWER) coughing
wheezing
shortness of breath
rapid breathing
chest tightness
Pathophysiology of asthma (5) (CORRECT ANSWER) -airway
inflammation, bronchial hyper-reactivity and smooth muscle spasm
-excess mucus production and accumulation
-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
,Bronchioles (CORRECT ANSWER) smaller passageways that originate
from the bronchi that become the alveoli
3 layers of the bronchioles (CORRECT ANSWER) innermost layer
middle layer - lamina propria
outermost layer
lamina propria (CORRECT ANSWER) the middle layer of the
bronchioles
structure of the lamina propria (CORRECT ANSWER) embedded with
connective tissue cells and immune cells
purpose of the lamina propria (CORRECT ANSWER) white blood cells
are present to help protect the airways
How does the lamina propria effect the lungs in regards to asthma
(CORRECT ANSWER) the WBCs protective feature goes into
overdrive causing an inflammatory response that damages host tissue
What does the innermost layer of the bronchioles contain (CORRECT
ANSWER) columnar epithelial ells and mucus producing goblet cells
What does the outermost layer of the bronchioles contain (CORRECT
ANSWER) smooth muscle cells
, what does the outermost layer of the bronchioles do (CORRECT
ANSWER) control the airways ability to constrict and dilate
alveolar hyperinflation (CORRECT ANSWER) When air is unable to
move out of the alveolar like it should due to bronchial walls collapsing
around possible mucus plug thus trapping air inside
how does hyperinflation occur? (CORRECT ANSWER) the ongoing
inflammatory process of asthma produces mucus and pus plug that the
bronchial walls collapse around
Effect of hyperinflation of the alveolar (CORRECT ANSWER) -
expanded thorax and hypercapnia (retention of CO2)
- respiratory acidosis
What are two anticholinergic drugs used for asthma (CORRECT
ANSWER) tiotropium and ipratropium
What do anticholinergics do in the lungs? (CORRECT ANSWER)
These drugs block the effects of the parasympathetic nervous system
- increasing bronchodilation
MOA of anticholinergic drugs for asthma (CORRECT ANSWER) the
parasympathetic system is stimulated by the vagal nerve to release
