4 classes of B Lactams - ANSWER✔✔-penicillins
cephalosporins
monobactams
carbapenems
MOA of B lactams - ANSWER✔✔-inhibit cell wall synthesis
4 subclasses of penicillins - ANSWER✔✔-natural
AminoPCN
PCNase resistant
anti-pseudomonal
are penicillins time or concentration dependent - ANSWER✔✔-time
examples of natural pcn - ANSWER✔✔-pcn G
pcn V
examples of AminoPCN - ANSWER✔✔-ampicillin
amoxicillin
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,examples of PCNase resistant - ANSWER✔✔-naficillin
oxacillin
dicloxacillin
examples of anti-pseudomonal - ANSWER✔✔-piperacillin
tircarcillin
coverage of natural PCN - ANSWER✔✔-mainly gram +
few gram -
coverage of AminoPCN - ANSWER✔✔-gram + and -
coverage of PCNase resistant - ANSWER✔✔-gram +
coverage of anti-pseudomonal - ANSWER✔✔-gram -
PCNase R or S -- natural - ANSWER✔✔-Sens
PCNase R or S -- AminoPCN - ANSWER✔✔-Sens
PCNase R or S -- PCNase resistant - ANSWER✔✔-Resistant
PCNase R or S -- anti-pseudomonal - ANSWER✔✔-Sens
DOC for syphillis - ANSWER✔✔-natural PCN
what shape is syphillis - ANSWER✔✔-spirochete
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, DOC for otitis media - ANSWER✔✔-amoxicillin
DOC for strep pharyngitis - ANSWER✔✔-amoxicillin
DOC for endocarditis prophylaxis - ANSWER✔✔-amoxicillin
DOC for mastitis - ANSWER✔✔-dicloxacillin
main use of anti-pseudomonal pcns - ANSWER✔✔-severe infection or pseudomonas
how are PCN eliminated from the body - ANSWER✔✔-renal
EXCEPT "NO" -- nafcillin and oxacillin which are hepatic
MC adverse effect of PCN - ANSWER✔✔-GI distress (n/v/d)
are PCN bacteriostatic or bactericidal - ANSWER✔✔-bactericidal
what do bacteria produce to combat beta lactams - ANSWER✔✔-beta lactamase
how do we counter beta lactamase - ANSWER✔✔-beta lactamase inhibitor (ex.
augmentin : amoxicillin + clavulanate)
examples of 1st gen cephalosporin - ANSWER✔✔-cefazolin
cephalexin
examples of 2nd gen cephalosporins - ANSWER✔✔-cefaclor
cefuroxime
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