VGI- Roach's Introductory Clinical Pharmacology - CH 1
Questions with Answers
Absorption - correct answers>>A drug moved from site of administration to body fluids.
Adverse Reaction - correct answers>>Undesirable drug effect
Allergic reaction - correct answers>>Immediate hypersensitivity reaction w/symptoms; it presents as
itching hives swelling & difficulty breathing
Anaphylactic shock - correct answers>>sudden, severe hypersensitivity reaction w/symptoms that
progress rapidly and may result in death if not treated;
Angioedma - correct answers>>localized wheals or swellings in subcutaneous tissue or mucous
membranes, which may be due to an allergic response.
Controlled substances - correct answers>>Drugs that have the potential for abuse and dependency, both
physically and psychological
cumulative drug effect - correct answers>>When the body is unable to metabolize & excrete one dose of
a drug before the next is given
Distribution - correct answers>>drug moves from circulation to body tissue or a target site.
Drug idiosyncrasy - correct answers>>Any unusual or abnormal response the differs from the response
normally expected to a specific drug and dosage.
Drug tolerance - correct answers>>decreased response to a drug, requiring an increase in dosage to
achieve the desire effect
Excretion - correct answers>>elimination of a drug from the body
, First-pass effect - correct answers>>action by which an oral drug is absorbed and carried directly to the
liver, where it is inactived by enzymes before it enters the general blood stream.
Half-life - correct answers>>time required for the body to eliminate 50% of a drug
Herbal medicine - correct answers>>type of complementary/alternative therapy that uses plants or
herbs to treat various disorders
Hypersensitivity - correct answers>>undesirable reaction produced by a normal immune system
Metabolism - correct answers>>drug is changed to a form that can be excreted
Metabolite - correct answers>>inactive form of the original drug
nonprescription drugs - correct answers>>drugs that are designated by the U.S. Food and Drug
administration (FDA) to be safe (if taken as directed) and obtained w/o a prescription
Pharmaceutic - correct answers>>Pertaining to the phase during which a drug dissolves in the body
Pharmacodtnamics - correct answers>>Study of the drug mechanisms that produce biochemical or
physiologic changes in the body
Pharmacokinetics - correct answers>>Study of the drug transit or activity after administration
Physical dependency - correct answers>>habitual use of a drug where negative physical withdraw
symptoms result from the abrupt discontinuation.
Prescription drugs - correct answers>>drugs the federal government has designated as potentially
harmful unless their use is supervised by a licensed health care provider, such as a nurse practitioner,
physician, or dentist.
Questions with Answers
Absorption - correct answers>>A drug moved from site of administration to body fluids.
Adverse Reaction - correct answers>>Undesirable drug effect
Allergic reaction - correct answers>>Immediate hypersensitivity reaction w/symptoms; it presents as
itching hives swelling & difficulty breathing
Anaphylactic shock - correct answers>>sudden, severe hypersensitivity reaction w/symptoms that
progress rapidly and may result in death if not treated;
Angioedma - correct answers>>localized wheals or swellings in subcutaneous tissue or mucous
membranes, which may be due to an allergic response.
Controlled substances - correct answers>>Drugs that have the potential for abuse and dependency, both
physically and psychological
cumulative drug effect - correct answers>>When the body is unable to metabolize & excrete one dose of
a drug before the next is given
Distribution - correct answers>>drug moves from circulation to body tissue or a target site.
Drug idiosyncrasy - correct answers>>Any unusual or abnormal response the differs from the response
normally expected to a specific drug and dosage.
Drug tolerance - correct answers>>decreased response to a drug, requiring an increase in dosage to
achieve the desire effect
Excretion - correct answers>>elimination of a drug from the body
, First-pass effect - correct answers>>action by which an oral drug is absorbed and carried directly to the
liver, where it is inactived by enzymes before it enters the general blood stream.
Half-life - correct answers>>time required for the body to eliminate 50% of a drug
Herbal medicine - correct answers>>type of complementary/alternative therapy that uses plants or
herbs to treat various disorders
Hypersensitivity - correct answers>>undesirable reaction produced by a normal immune system
Metabolism - correct answers>>drug is changed to a form that can be excreted
Metabolite - correct answers>>inactive form of the original drug
nonprescription drugs - correct answers>>drugs that are designated by the U.S. Food and Drug
administration (FDA) to be safe (if taken as directed) and obtained w/o a prescription
Pharmaceutic - correct answers>>Pertaining to the phase during which a drug dissolves in the body
Pharmacodtnamics - correct answers>>Study of the drug mechanisms that produce biochemical or
physiologic changes in the body
Pharmacokinetics - correct answers>>Study of the drug transit or activity after administration
Physical dependency - correct answers>>habitual use of a drug where negative physical withdraw
symptoms result from the abrupt discontinuation.
Prescription drugs - correct answers>>drugs the federal government has designated as potentially
harmful unless their use is supervised by a licensed health care provider, such as a nurse practitioner,
physician, or dentist.
