HOSMERIT
ANESTHESIA PRACTICE QUESTIONS AND ANSWERS
COMPLETE SOLUTION
Which cases the LEAST respiratory depression?
A. Ketamine
B. Etomidate
C. Midazolam
D. Propanol ✔✔A. Ketamine
Which has a pharmacologically inactive metabolite?
A. Ketamine
B. Midazolam
C. Propanol
D. Morphine ✔✔C. Propanol
Which anticholinesterase has an onset of action similar to atropine?
A. Neostigmine
B. Edrophonium
C. Pyridostigmine
D. Physostigmine ✔✔B. Edrophonium
All of these are side effects of anticholinesterase agents EXCEPT?
A. Bradycardia
B. Increased peristalsis
C. Increased salivation
D. Bronchodilation ✔✔D. Bronchodilation
Which is mostly really eliminated?
A. Rocuronium
B. Vecuronium
C. Pancuronium
D. Cisatracurium ✔✔C. Pancuronium
All these agents are mainly metabolized by plasma cholinesterase EXCEPT?
A. Remifentanil
B. Succinylcholine
C. Chloroprocaine
D. Tetra Caine ✔✔A. Remifentanil
Which is NOT a side effect of Dexmedetomidine?
A. Bradycardia
B. Sedation
C. Hypertension
,D. Increased gastric emptying ✔✔D. Increased gastric emptying
Which is TRUE about succinylcholine?
A. May cause hypokalemia
B. Reduces intraocular pressure
C. Reduces intragastric pressure
D. Associated with histamine release ✔✔D. Associated with histamine release
Which potentiates neuromuscular blockers?
A. Carbamazepine
B. Corticosteroids
C. Hypothermia
D. Alkalosis ✔✔C. Hypothermia
Enzyme responsible for the hydrolysis of succinylcholine?
A. Alkaline phosphatase
B. Acid phosphatase
C. Acetylcholinesterase
D. Pseudocholinesterase ✔✔D. Pseudocholinesterase
This cytotoxic agent may cause a dose-related progressive pulmonary fibrosis:
A. Doxorubicin
B. Bleomycin
C. Methotrexate
D. Cyclophosphamide ✔✔B. Bleomycin
Which inhibits plasma cholinesterase prolonging the duration of action of agents such as
succinylcholine?
A. Cyclophosphamide
B. Methotrexate
C. Ketorolac
D. Acetaminophen ✔✔A. Cyclophosphamide
High doses are associated with cardiomyopathy, especially in those with cardiac disease:
A. Bleomycin
B. Cyclophosphamide
C. Doxorubicin
D. Methotrexate ✔✔C. Doxorubicin
Which may increase the toxic potential of methotrexate, and the two agents should not be
combined?
A. Propofol
B. Sevoflurane
C. Ondansentron
D. Nitrous Oxide ✔✔D. Nitrous Oxide
, The risk of ototoxicity and nephrotoxicity from aminoglycosides is increased in the presence of:
A. Acetaminophen
B. Furosemide
C. Ondansentron
D. Fentanyl ✔✔B. Furosemide
Associated with formation of N-acetyl-p-benzoquinone and toxicity due to depletion of
glutathione:
A. Tramadol
B. Acetaminophen
C. Aspirin
D. Ibuprofen ✔✔B. Acetaminophen
Irreversibility inhibits cyclooxyrgenase:
A. Acetaminophen
B. Ibuprofen
C. Aspirin
D. Naproxen ✔✔C. Aspirin
Which is converted from water-soluble to lipid-soluble after exposure to bloodstream?
A. Ketamine
B. Fentanyl
C. Midazolam
D. Propofol ✔✔C. Midazolam
Which can cause extra pyramidal reactions?
A. Ondansentron
B. Metoclopramide
C. Omeprazole
D. Misoprostol ✔✔B. Metoclopramide
MAC of inhalation agents are higher in:
A. Infants
B. Young adults
C. Pregnancy
D. Elderly ✔✔A. Infants
Which should be avoided in patients with pulmonary hypertension?
A. Desflurane
B. Sevoflurane
C. Propofol
D. Nitrous oxide ✔✔D. Nitrous oxide
Which is TRUE about the non-ionized form of local anesthetics?
ANESTHESIA PRACTICE QUESTIONS AND ANSWERS
COMPLETE SOLUTION
Which cases the LEAST respiratory depression?
A. Ketamine
B. Etomidate
C. Midazolam
D. Propanol ✔✔A. Ketamine
Which has a pharmacologically inactive metabolite?
A. Ketamine
B. Midazolam
C. Propanol
D. Morphine ✔✔C. Propanol
Which anticholinesterase has an onset of action similar to atropine?
A. Neostigmine
B. Edrophonium
C. Pyridostigmine
D. Physostigmine ✔✔B. Edrophonium
All of these are side effects of anticholinesterase agents EXCEPT?
A. Bradycardia
B. Increased peristalsis
C. Increased salivation
D. Bronchodilation ✔✔D. Bronchodilation
Which is mostly really eliminated?
A. Rocuronium
B. Vecuronium
C. Pancuronium
D. Cisatracurium ✔✔C. Pancuronium
All these agents are mainly metabolized by plasma cholinesterase EXCEPT?
A. Remifentanil
B. Succinylcholine
C. Chloroprocaine
D. Tetra Caine ✔✔A. Remifentanil
Which is NOT a side effect of Dexmedetomidine?
A. Bradycardia
B. Sedation
C. Hypertension
,D. Increased gastric emptying ✔✔D. Increased gastric emptying
Which is TRUE about succinylcholine?
A. May cause hypokalemia
B. Reduces intraocular pressure
C. Reduces intragastric pressure
D. Associated with histamine release ✔✔D. Associated with histamine release
Which potentiates neuromuscular blockers?
A. Carbamazepine
B. Corticosteroids
C. Hypothermia
D. Alkalosis ✔✔C. Hypothermia
Enzyme responsible for the hydrolysis of succinylcholine?
A. Alkaline phosphatase
B. Acid phosphatase
C. Acetylcholinesterase
D. Pseudocholinesterase ✔✔D. Pseudocholinesterase
This cytotoxic agent may cause a dose-related progressive pulmonary fibrosis:
A. Doxorubicin
B. Bleomycin
C. Methotrexate
D. Cyclophosphamide ✔✔B. Bleomycin
Which inhibits plasma cholinesterase prolonging the duration of action of agents such as
succinylcholine?
A. Cyclophosphamide
B. Methotrexate
C. Ketorolac
D. Acetaminophen ✔✔A. Cyclophosphamide
High doses are associated with cardiomyopathy, especially in those with cardiac disease:
A. Bleomycin
B. Cyclophosphamide
C. Doxorubicin
D. Methotrexate ✔✔C. Doxorubicin
Which may increase the toxic potential of methotrexate, and the two agents should not be
combined?
A. Propofol
B. Sevoflurane
C. Ondansentron
D. Nitrous Oxide ✔✔D. Nitrous Oxide
, The risk of ototoxicity and nephrotoxicity from aminoglycosides is increased in the presence of:
A. Acetaminophen
B. Furosemide
C. Ondansentron
D. Fentanyl ✔✔B. Furosemide
Associated with formation of N-acetyl-p-benzoquinone and toxicity due to depletion of
glutathione:
A. Tramadol
B. Acetaminophen
C. Aspirin
D. Ibuprofen ✔✔B. Acetaminophen
Irreversibility inhibits cyclooxyrgenase:
A. Acetaminophen
B. Ibuprofen
C. Aspirin
D. Naproxen ✔✔C. Aspirin
Which is converted from water-soluble to lipid-soluble after exposure to bloodstream?
A. Ketamine
B. Fentanyl
C. Midazolam
D. Propofol ✔✔C. Midazolam
Which can cause extra pyramidal reactions?
A. Ondansentron
B. Metoclopramide
C. Omeprazole
D. Misoprostol ✔✔B. Metoclopramide
MAC of inhalation agents are higher in:
A. Infants
B. Young adults
C. Pregnancy
D. Elderly ✔✔A. Infants
Which should be avoided in patients with pulmonary hypertension?
A. Desflurane
B. Sevoflurane
C. Propofol
D. Nitrous oxide ✔✔D. Nitrous oxide
Which is TRUE about the non-ionized form of local anesthetics?
