BMS 602 - Exam #3 Questions and
Answers 100% Solved
How does E.coli become virulent? - ✔✔acquires virulence factors via
horizontal gene transfer
What does E.coli ferment? - ✔✔lactose, sucrose and glucose
What are the characteristics of E.coli on MacConkey agar and TSI? -
✔✔red colonies on MacConkey agar and yellow TSI slants
What kind of hemolysis does E.coli cause? - ✔✔beta
Is E.coli motile? - ✔✔yes
What is the most common disease caused by E.coli? - ✔✔gastroenteritis
which is caused by ingestion of contaminated food or water
self limiting
What kind of pathogen is E.coli? - ✔✔opportunistic
What are some ways that E.coli is an opportunistic pathogen? -
✔✔perforation of the intestine allows bacteria to infect the peritoneal cavity
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improper hygiene allows bacteria to cause UTO
Is E.coli gram positive or negative? - ✔✔gram negative
What is the shape of E.coli? - ✔✔rod
Where is E.coli normally found? - ✔✔human, animals, soil and water
How does E.coli enter the body? - ✔✔ingestion, wound infection or
endogenous spreading
for EPEC there is human to human spread
Where does E.coli multiply in the body? - ✔✔extracellular growth on
intestine, urogenital tract, blood, meninges, etc.
enteroinvasive replicates intracellularly
What are the two groups that E.coli virulence factors can be broken down
to? - ✔✔adhesins and exotoxins
What is ETEC? - ✔✔enterotoxigenic E. coli
traveler's diarrhea, infant diarrhea
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What are the symptoms of ETEC? - ✔✔watery diarrhea, vomiting, cramps,
nausea and low grade fever
How is ETEC acquired? - ✔✔ingestion of contaminated food or water
NO person to person spread
What is the incubation period for ETEC? - ✔✔1-2 days
watery diarrhea persists for 3-5 days
What is the treatment for ETEC? - ✔✔none, self limiting but given
rehydration therapy
antibiotics used for elderly, pregnant women, immunosuppressed and
young children
What is the mechanism of action of ETEC? - ✔✔1) attaches to microvilli via
colonizing factor adhesin (CFA)
2) CFA a pilus binds to glycoprotein receptor on the surface
3) bacteria releases heat labile toxin (LT-1) and heat stable toxin (STa)