APHA NAPLEX
Which of the following is not a potential source of physical or chemical
incompatibility?
A. dilution of a drug in a cosolvent system into an aqueous solution
B. addition of a drug solution with a high pH into a solution with a low pH
C. adsorption of a lipid-soluble drug into the matrix of a polypropylene container
D. a photosensitive drug such as sodium nitroprusside is D5W exposed to light
E. leaching of phthalate plasticizer into the solution from a PVC container -
ANSWERS-C. Absoprtion of a lipid soluble drug into the matrix of PVC containers
does occur. Polypropylene and polyethylene contain little or not plasticizer
Which of the following radiopharmaceuticals is indicated to image beta-amyloid
neuritic plaques in patients exhibiting cognitive impairment?
A. Tc-99m DTPA
B. Tc-99m biscisate
C. In-111 DTPA
D. Florbetapir F-18 - ANSWERS-D. Florbetapir F-18 is the only one with the
indication. Tc-99m DPTA is used to evaluate patients for brain death and Tc-99m
bicisate is used for evaluation of stroke patients in the evaluation of brain death.
In-111 DTPA is indicated for cisternography studies
,Which of the following radiopharmaceuticals is a controlled substance?
A. I-123 ioflupane
B. Florbetapir F-18
C. Thallous chloride T1-201
D. Tc-99m exametazime - ANSWERS-A. I-123 ioflupane is the only one is a
controlled drug
Which of the following radiopharmaceuticals accumulates in viable myocardial via
the Na/K ATPase pump?
A. F-18 FDG
B. Tc-99m tertrofsmin
C. Rb-82 chloride
D. Tc-99m sestamibi - ANSWERS-C. F-18 FDG is transported via glucose
transporters, Tc-99m tetrofosmin and Tc-99m sestamibi enter the cell via passive
diffusion
Which of the following radiopharmaceuticals is a monovalent cation and a
potassium analog?
A. F-18 FDG
,B. Tc-99m tetrofosmin
C. Tc-99m sestamibi
D. Thallous chloride T1-201 - ANSWERS-D. F-18 FDG is a glucose analog; Tc-99m
tetrofosmin and Tc-99m sestamibi are monovalent cations but not potassium
analogs; thallous chloride T1-201 is a monovalent cation and a potassium analog
Which of the following PET radiopharmaceuticals is commercially available from a
generator?
A. F-18 FDG
B. I-23 ioflupane
C. Florbetapir F-18
D. Rb-82 chloride - ANSWERS-D. F-18 and I-123 are not available from a generator
Which of the following is a myocardial radiopharmaceutical that provides
information on both perfusion and left ventricular function?
A. Rb-82 chloride
B. Tc-99m tetrofosmin
C. F-18 FDG
D. Thallous chloride T1-201 - ANSWERS-B. F-18 FDG is an indicator of metabolism,
Rb-82 chloride and thallous chloride provide information on myocardial perfusion.
Tc-99m tetrofosmin provides information on both myocardial perfusion and left
ventricular fn
, An example of a diagnostic skeletal agent is
A. Tc-99m bicisate
B. Tc-99m MDP
C. Sr-82 chloride
D. Florbetapir F-18 - ANSWERS-B. Tc-99m bicisate and florbetapir F-18 are for CNS
imaging. Sr 82 chloride is a palliative therapeutic agent
What patient preparation is recommended for skeletal imaging if the patient's
condition permits?
A. bowel cleansing
B. hydration
C. thyroid blockade
D. sincalide administration - ANSWERS-B. Hydration is recommended.
Which of the following correctly characterizes Tc-99m HDP?
A. localizes in areas of high bone metabolic activity
B. limited to use in adult patients with metastatic lesions
C. frequent adverse reactions
Which of the following is not a potential source of physical or chemical
incompatibility?
A. dilution of a drug in a cosolvent system into an aqueous solution
B. addition of a drug solution with a high pH into a solution with a low pH
C. adsorption of a lipid-soluble drug into the matrix of a polypropylene container
D. a photosensitive drug such as sodium nitroprusside is D5W exposed to light
E. leaching of phthalate plasticizer into the solution from a PVC container -
ANSWERS-C. Absoprtion of a lipid soluble drug into the matrix of PVC containers
does occur. Polypropylene and polyethylene contain little or not plasticizer
Which of the following radiopharmaceuticals is indicated to image beta-amyloid
neuritic plaques in patients exhibiting cognitive impairment?
A. Tc-99m DTPA
B. Tc-99m biscisate
C. In-111 DTPA
D. Florbetapir F-18 - ANSWERS-D. Florbetapir F-18 is the only one with the
indication. Tc-99m DPTA is used to evaluate patients for brain death and Tc-99m
bicisate is used for evaluation of stroke patients in the evaluation of brain death.
In-111 DTPA is indicated for cisternography studies
,Which of the following radiopharmaceuticals is a controlled substance?
A. I-123 ioflupane
B. Florbetapir F-18
C. Thallous chloride T1-201
D. Tc-99m exametazime - ANSWERS-A. I-123 ioflupane is the only one is a
controlled drug
Which of the following radiopharmaceuticals accumulates in viable myocardial via
the Na/K ATPase pump?
A. F-18 FDG
B. Tc-99m tertrofsmin
C. Rb-82 chloride
D. Tc-99m sestamibi - ANSWERS-C. F-18 FDG is transported via glucose
transporters, Tc-99m tetrofosmin and Tc-99m sestamibi enter the cell via passive
diffusion
Which of the following radiopharmaceuticals is a monovalent cation and a
potassium analog?
A. F-18 FDG
,B. Tc-99m tetrofosmin
C. Tc-99m sestamibi
D. Thallous chloride T1-201 - ANSWERS-D. F-18 FDG is a glucose analog; Tc-99m
tetrofosmin and Tc-99m sestamibi are monovalent cations but not potassium
analogs; thallous chloride T1-201 is a monovalent cation and a potassium analog
Which of the following PET radiopharmaceuticals is commercially available from a
generator?
A. F-18 FDG
B. I-23 ioflupane
C. Florbetapir F-18
D. Rb-82 chloride - ANSWERS-D. F-18 and I-123 are not available from a generator
Which of the following is a myocardial radiopharmaceutical that provides
information on both perfusion and left ventricular function?
A. Rb-82 chloride
B. Tc-99m tetrofosmin
C. F-18 FDG
D. Thallous chloride T1-201 - ANSWERS-B. F-18 FDG is an indicator of metabolism,
Rb-82 chloride and thallous chloride provide information on myocardial perfusion.
Tc-99m tetrofosmin provides information on both myocardial perfusion and left
ventricular fn
, An example of a diagnostic skeletal agent is
A. Tc-99m bicisate
B. Tc-99m MDP
C. Sr-82 chloride
D. Florbetapir F-18 - ANSWERS-B. Tc-99m bicisate and florbetapir F-18 are for CNS
imaging. Sr 82 chloride is a palliative therapeutic agent
What patient preparation is recommended for skeletal imaging if the patient's
condition permits?
A. bowel cleansing
B. hydration
C. thyroid blockade
D. sincalide administration - ANSWERS-B. Hydration is recommended.
Which of the following correctly characterizes Tc-99m HDP?
A. localizes in areas of high bone metabolic activity
B. limited to use in adult patients with metastatic lesions
C. frequent adverse reactions
